Abstracts tagged "lungs"

Abstract Number: 2859 • 2019 ACR/ARP Annual Meeting
Citrulline Reactive B Cells Are Present in the Lungs of Early Untreated RA
Vijay Joshua¹, Malena Loberg-Haarhaus ¹, Heidi Wähämaa ², Aase Hensvold ², Khaled Amara ¹, Lena Israelsson ¹, Ragnhild Stålesen ¹, Magnus Sköld ³, Johan Grunewald ³, Caroline Grönwall ¹, Vivianne Malmström ¹ and Anca Catrina ⁴, ¹Rheumatology Unit, Department of Medicine, Karolinska University Hospital and Institutet, Stockholm, Sweden., Stockholm, Sweden, ²Rheumatology unit Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, Stockholm, ³Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden., Stockholm, Sweden, ⁴Rheumatology unit Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, Stockholm, Sweden
Background/Purpose: Structural changes, increased tissue citrullination, signs of local inflammation and anti-citrullinated protein autoantibodies (ACPA) are present in the pulmonary compartment of early untreated seropositive…

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