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Abstracts tagged "Lung Fibrosis"

  • Abstract Number: 1858 • ACR Convergence 2021

    Serum Interferon Score Is a Biomarker of Active Disease in Patients with Early Diffuse Cutaneous Systemic Sclerosis Enrolled in the Prospective Registry of Early Systemic Sclerosis (PRESS) Cohort

    Monique Hinchcliff1, Suiyuan Huang2, Shervin Assassi3, Elana Bernstein4, Flavia Castelino5, Robyn Domsic6, Tracy Frech7, Jessica Gordon8, Faye Hant9, Ami Shah10, Victoria Shanmugam11, Virginia Steen12, Dinesh Khanna2 and Francesco Del Galdo13, 1Yale School of Medicine, Westport, CT, 2University of Michigan, Ann Arbor, MI, 3University of Texas McGovern Medical School at Houston, Houston, TX, 4Columbia University, New York, NY, 5Massachusetts General Hospital, Boston, MA, 6University of Pittsburgh, Pittsburgh, PA, 7University of Utah, Salt Lake City, UT, 8Hospital for Special Surgery, New York, NY, 9Medical University of South Carolina, Charleston, SC, 10Johns Hopkins Rheumatology, Baltimore, MD, 11The George Washington University, Great Falls, VA, 12Division of Rheumatology, Georgetown University, Washington, DC, 13University of Leeds, Leeds, United Kingdom

    Background/Purpose: Several published studies have demonstrated activation of the interferon type 1 (IFN) pathway in sera from patients with systemic sclerosis (SSc). Specifically, levels of…

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