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Abstracts tagged "Lung Disease and systemic sclerosis"

  • Abstract Number: 1715 • 2017 ACR/ARHP Annual Meeting

    Mitochondrial DNA Mutations and Respiratory Chain Dysfunction in Lung Fibrosis of Systemic Sclerosis

    Veronika K. Jaeger1, Dirk Lebrecht2,3, Andrew G. Nicholson4,5, Athol U Wells5,6, Suresh George7, Amiq Gazdhar8, Michael Tamm9, Nils Venhoff2, Thomas Geiser8 and Ulrich A. Walker1, 1Department of Rheumatology, University Hospital Basel, Basel, Switzerland, 2Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, 3Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany, 4Department of Histopathology, Royal Brompton Hospital, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom, 5National Heart and Lung Institute, Imperial College, London, United Kingdom, 6Interstitial Lung Disease Unit, Royal Brompton Hospital, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom, 7Royal Brompton and Harefield National Health Service Foundation Trust, London, United Kingdom, 8Department of Pulmonary Medicine, University Hospital Bern, Bern, Switzerland, 9Department of Pneumology, University Hospital Basel, Basel, Switzerland

    Background/Purpose: Recent data have implemented reactive oxygen species (ROS) in the etiology of interstitial lung disease (ILD) in systemic sclerosis. Recent data from bleomycin mice…
  • Abstract Number: 678 • 2013 ACR/ARHP Annual Meeting

    Quantifying Change In Pulmonary Function As a Prognostic Marker In Systemic Sclerosis-Related Interstitial Lung Disease

    Owen Moore1,2, Susanna Proudman3, Nicole Goh4, Tamera Corte5, Hannah Rouse6, Oliver Hennessy6, Vivek Thakkar7, Joanne Sahhar8, Janet E. Roddy9, Peter Youssef10, Eli Gabbay11, Peter Nash12, Jane Zochling13, Wendy Stevens14 and Mandana Nikpour15, 1Rheumatology, St. Vincent’s Hospital, Melbourne, Australia, 2Rheumatology, Derriford Hospital, Plymouth, United Kingdom, 3Rheumatology Unit, Royal Adelaide Hospital, Adelaide, Australia, 4Department of Respiratory Medicine, Alfred Hospital, Melbourne, Australia, 5Department of Respiratory Medicine, Royal Prince Alfred Hospital, Sydney, Australia, 6Department of Radiology, St. Vincent’s Hospital, Melbourne, Australia, 7St Vincent's Hospital, Melbourne, Australia, 8Rheumatology Unit, Monash Medical Centre, Clayton, Australia, 9Royal Perth Hospital, Perth, Australia, 10Department of Rheumatology, Royal Prince Alfred Hospital, Sydney, Australia, 11Advanced Lung Disease Unit, Royal Perth Hospital, Perth, Australia, 12Rheumatology Research Unit, Nambour Hospital, Sunshine Coast, Australia, 13Menzies Research Institute Tasmania, Hobart, Australia, 14Rheumatology, St Vincent's Hospital, Melbourne, Australia, 15Department of Medicine (St Vincent's Hospital), University of Melbourne, Fitzroy, Australia

    Background/Purpose: Interstitial lung disease (ILD) is a leading cause of mortality in systemic sclerosis (SSc) but it is not severe or progressive in all patients.…
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