Abstracts tagged "lipids and rheumatoid arthritis (RA)"

Abstract Number: 2658 • 2015 ACR/ARHP Annual Meeting
Low Disease Activity Is Associated with Higher HDL and a Trend to Lower Insulin Resistance in Rheumatoid Arthritis Patients
Androniki Bili¹, Debra Webb¹, Cynthia Matzko², Andrea Berger³, Eric Newman⁴, Thomas Olenginski⁴, H. Lester Kirchner³, Jon Giles⁵ and Mary Chester M. Wasko⁶, ¹Rheumatology, Geisinger Medical Center, Danville, PA, ²Rheumatology MC 13-41, Geisinger Medical Center, Danville, PA, ³Biostatistics, Geisinger Center for Health Research, Danville, PA, ⁴Department of Rheumatology, Geisinger Medical Center, Danville, PA, ⁵Columbia University Medical Center, New York, NY, ⁶West Penn Allegheny Health System, Temple University School of Medicine, Pittsburgh, PA
Background/Purpose: Treat to target (T2T) trials in RA to date have focused on the effect of T2T on articular disease without directly addressing cardiovascular risk.…
Abstract Number: 2889 • 2014 ACR/ARHP Annual Meeting
The Association Between Changes in Inflammation and High Density Lipoprotein Cholesterol Efflux Capacity in Rheumatoid Arthritis
K P Liao¹, Martin Playford², Michelle A. Frits³, Christine K. Iannaccone⁴, Jonathan S. Coblyn¹, Michael E. Weinblatt⁵, Nancy A. Shadick⁶ and Nehal N. Mehta⁷, ¹Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ²National Heart, Blood, and Lung Institute, Bethesda, MD, ³Division of Rheumatology, Brigham and Women's Hospital, Boston, MA, ⁴Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ⁵Division of Rheumatology & Immunology, Brigham and Women's Hospital, Boston, MA, ⁶Brigham and Women's Hospital/Harvard University, Cambridge, MA, ⁷Division of Cardiovascular Medicine, University of Pennsylvania, Philadelphia, PA
Background/Purpose: High density lipoprotein (HDL) cholesterol efflux capacity measures the functional ability of HDL to remove cholesterol from atherosclerotic plaque. Low HDL efflux capacity is…
Abstract Number: 2374 • 2014 ACR/ARHP Annual Meeting
Use of Hydroxychloroquine Associated with Improved Lipid Profile in Rheumatoid Arthritis Patients
Jose Felix Restrepo¹, Inmaculada del Rincon², Emily Molina³, Daniel Battafarano⁴ and Agustin Escalante⁵, ¹Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, TX, ²Medicine/Clinical Immunology, UTHSCSA, San Antonio, TX, ³Rheumatology, University of Texas Health Science Center, San Antonio, TX, ⁴Rheumatology, San Antonio Military Medical Center, JBSA - Ft Sam Houston, TX, ⁵Medicine-Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, TX
Background/Purpose: Cardiovascular disease (CVD) is one of the leading causes of morbidity and mortality in rheumatoid arthritis (RA). CVD risk factor reduction, such as reducing…
Abstract Number: 1395 • 2014 ACR/ARHP Annual Meeting
Disease Activity Is Associated with Insulin Resistance in Early Rheumatoid Arthritis
Androniki Bili¹, Debra Webb², Cynthia Matzko³, Andrea Berger⁴, Eric D. Newman⁵, Thomas P. Olenginski⁶, David M. Pugliese⁷, Maria Butterwick⁸, Lisa L. Schroeder¹, Thomas M. Harrington⁶, Jonida Cote¹, Lyudmila Kirillova¹, Susan Mathew¹, Tarun Sharma¹, H. Lester Kirchner⁹, Jon Giles¹⁰ and Mary Chester M. Wasko¹¹, ¹Rheumatology, Geisinger Health System, Danville, PA, ²Rheumatology, Geisinger Medical Center, Danville, PA, ³Rheumatology MC 13-41, Geisinger Medical Center, Danville, PA, ⁴Center for Health Research, Geisinger Health System, Danville, PA, ⁵Department of Rheumatology, Geisinger Health System, Danville, PA, ⁶Dept of Rheumatology, Geisinger Health System, Danville, PA, ⁷Rheumatology, Geisinger Health System, Wilkes-Barre, PA, ⁸Rheumatology, Geisinger Specialty Group, Wilkes-Barre, PA, ⁹Geisinger Center for Health Research, Geisinger Health System, Danville, PA, ¹⁰Columbia University Medical Center, New York, NY, ¹¹West Penn Allegheny Health System, Temple University School of Medicine, Pittsburgh, PA
Background/Purpose: Rheumatoid arthritis (RA) is a systemic disease that manifests mainly with articular symptoms, but the main cause of death is cardiovascular disease (CVD). Chronic…
Abstract Number: 843 • 2014 ACR/ARHP Annual Meeting
Exercise Is Associated with Protective Cardiovascular Risk Profile Including Increased HDL Particle Number in Patients with Rheumatoid Arthritis
Kevin Byram¹, Annette Oeser², MacRae F. Linton², Sergio Fazio², C Michael Stein² and Michelle Ormseth³, ¹Internal Medicine, Vanderbilt University, Nashville, TN, ²Vanderbilt University, Nashville, TN, ³Department of Medicine, Division of Rheumatology, Vanderbilt University, Nashville, TN
Background/Purpose: Patients with rheumatoid arthritis (RA) have increased cardiovascular risk. In the general population, exercise improves several cardiovascular risk factors, including HDL cholesterol concentrations. Although…
Abstract Number: 841 • 2014 ACR/ARHP Annual Meeting
Lipid Control and Cardiovascular Risk for Patients with Rheumatoid Arthritis Compared with Matched Non-Rheumatoid Arthritis Patients
J An¹, E Alemao², K Reynolds³, H Kawabata², D H Solomon⁴, K P Liao⁴ and T C Cheetham³, ¹Western University of Health Sciences, Pomona, CA, ²Bristol-Myers Squibb, Princeton, NJ, ³Kaiser Permanente Southern California, Pasadena, CA, ⁴Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Lipid levels are known to be lower in patients with RA compared with the general population; however, differences in cardiovascular (CV) risk associated with…
Abstract Number: 488 • 2014 ACR/ARHP Annual Meeting
Increases in Serum Cholesterol with Baricitinib Treatment Are Associated with Favorable Changes in Apolipoprotein Content and with Improvement in DAS28-CRP in Patients with Rheumatoid Arthritis
Joel M. Kremer¹, Mark C Genovese², Edward C. Keystone³, Peter C. Taylor⁴, Steven H. Zuckerman⁵, Douglas E. Schlichting⁵, Eric P. Nantz⁵, Scott D. Beattie⁵ and William L. Macias⁶, ¹Medicine, Albany Medical College and the Center for Rheumatology, Albany, NY, ²Division of Immunology and Rheumatology, Stanford University Medical Center, Palo Alto, CA, ³University of Toronto, Toronto, ON, Canada, ⁴NDORMS, Botnar Research Centre, University of Oxford, Oxford, United Kingdom, ⁵Eli Lilly and Company, Indianapolis, IN, ⁶Lilly Corporate Center, Eli Lilly and Company, Indianapolis, IN
Background/Purpose: Treatment with baricitinib (bari), an oral inhibitor of JAK1/JAK2, demonstrated improvements in signs and symptoms of RA through 52 wks in a Phase 2b…
Abstract Number: 1241 • 2012 ACR/ARHP Annual Meeting
Glucocorticoid use Is associated with increase in HDL in Rheumatoid Arthritis Patients
Lisa L. Schroeder¹, Xiaoqin Tang², Mary Chester M. Wasko³ and Androniki Bili⁴, ¹Rheumatology, Geisinger Health System, Danville, PA, ²Biostatistics, Geisinger Center for Health Research, Danville, PA, ³West Penn Allegheny Health System, Temple University School of Medicine, Pittsburgh, PA, ⁴Rheumatology, Geisinger Medical Center, Danville, PA
Glucocorticoid use is associated with increase in HDL in Rheumatoid Arthritis PatientsBackground/Purpose: Atherogenic lipid profiles are common in active RA, with most common being decreased…
Abstract Number: 416 • 2012 ACR/ARHP Annual Meeting
Dyslipidaemia in Early Rheumatoid Arthritis Patients Is Common and Not Influenced by Two Years of Effective DMARD Therapy. the Opera Study
Torkell Ellingsen¹, Kim Horslev-Petersen², Merete L. Hetland³, Peter Junker⁴, Jan Podenphant⁵, Mikkel Ostergaard⁶ and Kristian Stengaard-Pedersen⁷, ¹Diagnostic Center, Regional Hospital, Silkeborg, Denmark, ²Rheumatology, Research Unit at King Christian X Hospital for Rheumatic Diseases, Graasten, Graasten, Denmark, ³Copenhagen University Hospital Glostrup, Copenhagen, Denmark, ⁴Dept of Internal Med C/Rheum, Odense University Hospital, Denmark, ⁵Department of Rheumatology, Copenhagen University Hospital at Gentofte, Glostrup, Denmark, ⁶Dept of Rheumatology RM, Copenhagen University Hospital at Glostrup, Denmark, ⁷Rheumatology, Arhus University Hospital, Denmark
Background/Purpose: In a cohort of early ( 3.2 during year 2, sulphasalazine (SZS) and hydroxychloroquine (HCQ) were added to MTX and if active disease persisted…
Abstract Number: 2482 • 2012 ACR/ARHP Annual Meeting
Hydroxychloroquine Has Lipid-Lowering Effects in US Veterans with Rheumatoid Arthritis
Nicole A. Kieffer¹, Gail S. Kerr², J. Steuart Richards³, Lisa A. Davis⁴, Liron Caplan⁵, Jeffrey Huang⁶, Grant W. Cannon⁷, Harlan Sayles⁸ and Kaleb Michaud⁹, ¹Division of Rheumatology, Georgetown University, Washington, DC, ²Rheumatology, Washington DC VAMC, Georgetown and Howard University, Washington, DC, ³Rheumatology, Washington DC VA and Georgetown University, Washington, DC, ⁴Division of Rheumatology, Denver Health and Hospital Authority, Denver, CO, ⁵Div of Rheumatology, Denver VA and Univ of Colorado School of Medicine, Aurora, CO, ⁶Rheumatology, Washington DC VA and Howard University Hospital, Washington, DC, ⁷Division of Rheumatology, George E. Wahlen VA Medical Center, Salt Lake City, UT, ⁸Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, ⁹Rheumatology, National Data Bank for Rheumatic Diseases & University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Recent data report significant decreases in low-density lipoprotein (LDL) and total cholesterol (TC) levels in predominantly female Caucasian rheumatoid arthritis (RA) patients treated with…
Abstract Number: 1683 • 2012 ACR/ARHP Annual Meeting
Associations Between Lipid and Rheumatoid Arthritis Genetic Factors, and Low Density Lipoprotein Levels in RA Patients
Katherine P. Liao¹, Dorothee Diogo², Tianxi Cai³, Jing Cui⁴, Raul N. Guzman P.⁵, Vivian Gainer⁵, Shawn N. Murphy⁵, Susanne Churchill⁶, Isaac Kohane⁷, Elizabeth W. Karlson¹ and Robert M. Plenge⁸, ¹Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ²Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, ³Biostatistics, Harvard School of Public Health, Boston, MA, ⁴Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ⁵Research Computing, Partners Healthcare Systems, Boston, MA, ⁶Information Systems, Partners Healthcare Systems, Boston, MA, ⁷Medicine, Brigham and Women's Hospital, Boston, MA, ⁸Division of Rheumatology, Immunology and Allergy and Division of Genetics, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA
Associations between lipid and rheumatoid arthritis genetic factors, and low density lipoprotein levels in RA patientsBackground/Purpose: In epidemiologic studies, low density lipoprotein (LDL), a major…
Abstract Number: 1265 • 2012 ACR/ARHP Annual Meeting
Lipoprotein Subclass Particles and Small Vessel Elasticity As a Potential Marker for Early Atherosclerosis in Rheumatoid Arthritis: a Prospective, Controlled Study
Marty T. Mertens¹ and Elie Gertner², ¹Rheumatology, University of Minnesota, Minneapolis, MN, ²Section of Rheumatology, Regions Hospital and University of Minnesota Medical School, St. Paul, MN
Background/Purpose: Rheumatoid arthritis (RA) has increased rates of cardiovascular (CV) events. However, standard CV risk factors, such as routine lipid profiles, are not different in…
Abstract Number: 1268 • 2012 ACR/ARHP Annual Meeting
Lipid Alterations and Measurement of Arterial Stiffness in Rheumatoid Arthritis
Marina Scolnik¹, Carla Saucedo², David A. Navarta³, Leandro Ferreyra Garrott², Erika Catay⁴, Maria L. Acosta Felquer⁵, Eliana Lancioni⁶, Cristian Quiroz³, Federica Varela Guidetti⁵, Zaida Bedran², Mirtha Sabelli⁴, Javier Rosa⁴, Maria Victoria Garcia⁴, Patricia M. Imamura⁵, Patricia Sorroche⁷, Jose Alfie⁸, Margarita Morales⁹, Gabriel Waisman⁹, Luis J. Catoggio¹ and Enrique Soriano¹, ¹Rheumatology Section, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ²Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ³Internal Medicine, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁴Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁵Internal Medicine, Rheumatology Section, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁶Rheumatology Unit, Internal Medicine Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁷Central Laboratory , Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁸Internal Medicine, Hypertension Unit, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁹Hypertension Section, Internal Medicine Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina
Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disease. Increased arterial stiffness, an independent risk factor for premature coronary artery disease, has been reported in…

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