Abstracts tagged "line"

Abstract Number: 2039 • ACR/ARP Annual Meeting 2019
High Prevalence and Disease Correlation of Autoantibodies Against p40 Encoded by Long Interspersed Nuclear Elements (LINE-1) in SLE
Kennedy Ukadike¹, Victoria Carter ¹, John LaCava ², Martin Taylor ³, Anders Bengtsson ⁴, Christian Lood ¹ and Tomas Mustelin ¹, ¹University of Washington, Seattle, WA, ²The Rockefeller University, New York, NY, ³Massachusetts General Hospital, Boston, MA, ⁴Lund University, Lund, Sweden
Background/Purpose: The long interspersed nuclear element 1 (LINE-1) has two major open reading frames (ORFs): ORF1 encodes the RNA-binding p40 protein, and ORF2 encodes the…