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Abstracts tagged "leukocytes and systemic lupus erythematosus (SLE)"

  • Abstract Number: 760 • ACR/ARHP Annual Meeting 2016

    Effects of Type I Interferon Inhibition on Blood Leukocyte Subsets in Patients Treated in a Phase IIb Clinical Study of Anifrolumab in SLE

    Geoffrey Stephens1, Rong Zeng2, Xiang Guo2, Steve Eck3, Yuling Wu3, Liangwei Wang3, Gabor Illei3 and Wendy White2, 1Cellcion, Clarksburg, MD, 2Translational Sciences, MedImmune, LLC, Gaithersburg, MD, 3MedImmune, LLC, Gaithersburg, MD

    Background/Purpose: A Phase IIb randomized controlled study (NCT01753193) was conducted with anifrolumab, a fully human, anti-interferon (IFN)–α receptor (IFNAR1) specific antibody in adults with moderate…
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