Abstracts tagged "keratinocyte"

Abstract Number: 0999 • ACR Convergence 2021
UVB-irradiated Keratinocyte-derived Extracellular Vesicles Induced Proinflammatory Responses in Macrophages
Yubin Li¹, Thomas Vazquez², DeAnna Diaz³, Mariko Momohara⁴ and Victoria Werth⁴, ¹Corporal Michael J. Crescenz VAMC, Department of Dermatology, U Penn, Philadelphia, PA, ²FIU Wertheim College of Medicine, Virginia Beach, VA, ³Philadelphia College of Medicine, Philadelphia, PA, ⁴University of Pennsylvania, Philadelphia, PA
Background/Purpose: Ultraviolet B irradiation (UVB) contributes to skin inflammation. As UVB mostly affects the epidermis, with just 10% getting into the dermis, the crosstalk between…
Abstract Number: 2040 • 2019 ACR/ARP Annual Meeting
BATF2 Contributes to Interferon Dysregulation in SLE Keratinocytes
Jessica Turnier¹, Celine Berthier ¹, Lam Tsoi ¹, Danielle Barnes ¹, Grace Hile ¹, Tamra Reed ¹, Jianhua Liu ¹, Johann Gudjonsson ¹ and J. Michelle Kahlenberg ¹, ¹University of Michigan, Ann Arbor, MI
Background/Purpose: Skin inflammation can drive systemic disease in SLE, thus it is essential to understand the key regulators of the aberrant inflammatory response in lupus…

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