Abstracts tagged "juvenile spondylarthropathy"

Abstract Number: 123 • 2020 Pediatric Rheumatology Symposium
Juvenile Spondyloarthritis in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry: High Biologic Use, Low Prevalence of HLA-B27, and Equal Sex Representation in Those with Sacroiliitis
Dax Rumsey¹, Aimee Lougee ², Roland Matsouaka ², David Collier ³, Laura Schanberg ⁴, Jennifer Schenfeld ⁵, Natalie Shiff ⁶, Matthew Stoll ⁷, Scott Stryker ⁸, Pamela Weiss ⁹ and Timothy Beukelman ⁷ for the CARRA investigators, ¹University of Alberta, Edmonton, Canada, ²Duke University, Durham, ³Amgen, Thousand Oaks, ⁴Duke Children's Hospital & Health Center, Durham, North Carolina, ⁵Amgen, Long Beach, ⁶Florida, Gainesville, ⁷University of Alabama at Birmingham, Birmingham, ⁸Amgen, Inc, San Francisco, ⁹Children's Hospital of Philadelphia, Philadelphia
Background/Purpose: To describe characteristics of children with enthesitis-related arthritis (ERA) and juvenile psoriatic arthritis (JPsA) enrolled in the Childhood Arthritis and Rheumatology Research Alliance (CARRA)…
Abstract Number: 2713 • 2019 ACR/ARP Annual Meeting
Juvenile Spondyloarthritis in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry: High Biologic Use, Low Prevalence of HLA-B27, and Equal Sex Representation in Those with Sacroiliitis
Dax Rumsey¹, Aimee Lougee ², Roland Matsouaka ², David Collier ³, Laura Schanberg ⁴, Jennifer Schenfeld ⁵, Natalie Shiff ⁶, Matthew Stoll ⁷, Scott Stryker ³, Pamela F. Weiss ⁸ and Timothy Beukelman ⁹, ¹University of Alberta, Edmonton, AB, Canada, ²Duke University, Durham, NC, ³Amgen Inc., Thousand Oaks, CA, ⁴Duke University Medical Center, Durham, NC, ⁵Amgen, Inc, Thousand Oaks, CA, ⁶University of Florida, Gainesville, FL, ⁷University of Alabama at Birmingham, Birmingham, AL, ⁸Children's Hospital of Philadelphia, Philadelphia, PA, ⁹University of Alabama Birmingham, Birmingham, AL
Background/Purpose: Herein we describe characteristics of children with juvenile spondyloarthritis (JSpA, i.e. enthesitis-related arthritis [ERA] or juvenile psoriatic arthritis [JPsA]) enrolled in the Childhood Arthritis…
Abstract Number: 2334 • 2017 ACR/ARHP Annual Meeting
Hypermethylation of NLRP3 Promoter Region Could be Responsible for Decreased Gene Expression, Inflammasome Malfunction and Gut Dysbiosis in Juvenile Spondyloarthritis Patients
Lovro Lamot^1,2, Kristina Gotovac Jercic³, Antonela Blazekovic³, Mirta Lamot⁴, Mandica Vidovic⁴, Fran Borovecki³ and Miroslav Harjacek^3,4, ¹Department of Pediatrics, University of Zagreb School of Medicine, Zagreb, Croatia, ²Department of Pediatrics, Division of Clinical Immunology and Rheumatology, Clinical Hospital Center Sestre Milosrdnice, Zagreb, Croatia, ³University of Zagreb School of Medicine, Zagreb, Croatia, ⁴Clinical Hospital Center Sestre Milosrdnice, Zagreb, Croatia
Background/Purpose: Juvenile spondyloarthritis (jSpA) is a complex disease with both genetic and environmental factors contributing to the etiology. Recently obtained gene signatures in jSpA patients…
Abstract Number: 2805 • 2017 ACR/ARHP Annual Meeting
Juvenile-Onset Ankylosing Spondylitis Has a Lower Rate of Radiographic Progression Than Adult-Onset Ankylosing Spondylitis
Anthony So¹, Ammepa Anton², Florence Tsui³, Ismail Sari⁴, Renise Ayearst⁵, Robert D Inman⁶ and Nigil Haroon⁴, ¹University of British Columbia, Vancouver, BC, Canada, ²University Health Network, Toronto, ON, Canada, ³University of Toronto, Toronto, ON, Canada, ⁴Rheumatology, Toronto Western Hospital, University of Toronto, Spondylitis Clinic, Toronto, ON, Canada, ⁵Medicine, University Health Network, Toronto, ON, Canada, ⁶Department of Immunology, University of Toronto, Toronto, ON, Canada
Background/Purpose: There are no large radiographic follow up studies assessing progression in juvenile-onset Ankylosing Spondylitis (JoAS) as compared to adult-onset Ankylosing Spondylitis (AoAS). The purpose…
Abstract Number: 2304 • 2014 ACR/ARHP Annual Meeting
Positive HLA-B27 in Juvenile Spondyloarthritis Is Associated to Early Sacroiliitis and Progression to Ankylosing Spondylitis
Mariana O Perez¹, Nadia E Aikawa¹, Solange Carrasco¹, Percival D Sampaio-Barros², Celio R. Gonçalves², Carla G.S. Saad², Julio C. B. Moraes² and Cláudia Goldeinstein-Schainberg², ¹University of São Paulo, São Paulo, Brazil, ²Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Juvenile spondyloarthritis (JSpA) manifests with axial and peripheral involvement, enthesitis and HLAB27+ in 60-90% children. Radiological sacroiliitis may occur within 10 years, representing an…
Abstract Number: 2000 • 2012 ACR/ARHP Annual Meeting
Whole Body Magnetic Resonance Imaging in Evaluation of Enthesitis in Spondyloarthropathy
Hemalatha Srinivasalu¹, Suvimol C. Hill², Gina A. Montealegre Sanchez³, April D. Brundidge³, Michael M. Ward⁴ and Robert A. Colbert³, ¹Rheumatology, NIAMS NIH, Bethesda, MD, ²Radiology and Imaging Sciences, NIH Clinical Center, Bethesda, MD, ³NIAMS NIH, Bethesda, MD, ⁴Bldg 10 CRC Rm 4-1339, NIAMS NIH, Bethesda, MD
Background/Purpose: Enthesitis is a characteristic feature of spondyloarthritis (SpA). Tenderness at enthesial points constitutes clinical enthesitis. However, this may not always correlate with actual inflammation…

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