Abstracts tagged "juvenile idiopathic arthritis (JIA)"

Abstract Number: 1141 • 2012 ACR/ARHP Annual Meeting
Safety of Celecoxib and Non-Selective Non-Steroidal Anti-Inflammatory Drugs in Juvenile Idiopathic Arthritis
Rachel E. Sobel¹, D. J. Lovell², Hermine Brunner³, Jennifer E. Weiss⁴, Paula W. Morris⁵, Beth S. Gottlieb⁶, Elizabeth C. Chalom⁷, Lawrence K. Jung⁸, Karen Onel⁹, Lisa Petinoit¹⁰, Donald P. Goldsmith¹¹, Staci Abramsky-Risman¹², James P., Young¹³ and Edward H. Giannini¹⁴, ¹Epidemiology, Worldwide Safety Strategy, Pfizer, Inc., New York, NY, ²Cincinnati Children's Hospital, Cincinnati, OH, ³Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁴Pediatric Rheumatology, Hackensack Univ Med Ctr, Hackensack, NJ, ⁵Pediatrics, Univ of Arkansas for Med Sci, Little Rock, AR, ⁶Pediatric Rheumatology, Cohen Children's Medical Center of New York, New Hyde Park, NY, ⁷Pediatrics, St. Barnabas Medical Center, Livingston, NJ, ⁸Pediatric Rheumatology, Children's National Medical Center, Washington, DC, ⁹Pediatric Rheumatology, University of Chicago Hospitals, Chicago, IL, ¹⁰Pediatric Rheumatology, 'Specially for Children, Dell Children's Medical Center, Austin, TX, ¹¹Pediatric Rheumaology, St Christopher's Hospital for Children/ Drexel College of Medicine, Philadelphia, PA, ¹²Pfizer Inc, New York, NY, ¹³United BioSource Corporation, Ann Arbor, MI, ¹⁴Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: Celecoxib, a selective COX-2 inhibitor, was approved by the FDA for the treatment of the signs and symptoms of JIA in children aged 2-17…
Abstract Number: 2026 • 2012 ACR/ARHP Annual Meeting
High Prevalence of Cervical Spine and Temporomandibular Joint Involvement in Patients with Juvenile Idiopathic Arthritis
Nikolay Tzaribachev¹, Catrin Tzaribachev¹ and Bernd Koos², ¹Pediatric Rheumatology, Center for Rheumatic Diseases, Bad Bramstedt, Germany, ²Clinic of Orthodontics, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany
Background/Purpose: Detection of involvement of temporomandibular joints (TMJ), which are frequently affected by juvenile idiopathic arthritis (JIA), is only possible on Gadolinium enhanced MRI…
Abstract Number: 1155 • 2012 ACR/ARHP Annual Meeting
A New Measure of Visual Function for Children with Juvenile Idiopathic Arthritis-Associated Uveitis
Sheila T. Angeles-Han¹, Steven Yeh², Courtney McCracken¹, Larry B. Vogler³, Kelly A. Rouster-Stevens⁴, Christine W. Kennedy⁵, Kirsten Jenkins⁶, Matthew Kent³, Scott Lambert⁷, Carolyn Drews-Botsch⁸ and Sampath Prahalad⁹, ¹Emory University School of Medicine, Atlanta, GA, ²Ophthalmology, Emory University School of Medicine, Atlanta, GA, ³Dept of Pediatrics, Emory Univ School of Medicine, Atlanta, GA, ⁴Pediatric Rheumatology, Emory Univ School of Medicine, Atlanta, GA, ⁵Rheumatology Immunology, Emory Children's Center, Atlanta, GA, ⁶Children's Healthcare of Atlanta, Atlanta, GA, ⁷Ophthalmology, Emory Univ School of Medicine, Atlanta, GA, ⁸Epidemiology, Emory University School of Public Health, Atlanta, GA, ⁹Pediatrics, Emory Children's Center, Atlanta, GA
Background/Purpose: Studies on outcomes of children with juvenile idiopathic arthritis-associated uveitis (JIA-U) focus on the clinical ocular exam and physical disability secondary to arthritis. This…
Abstract Number: 2001 • 2012 ACR/ARHP Annual Meeting
Methotrexate and Injectable Tumor Necrosis Factor Alpha Inhibitor Adherence and Persistence in Children with Rheumatic Diseases
Sarah Ringold¹, Shannon Grant², Charmaine Girdish³, Carol A. Wallace⁴ and Sean Sullivan⁵, ¹Pediatrics, Seattle Children's Hospital/Univ of Washington, Seattle, WA, ²Axio Research LLC, Seattle, WA, ³Research, CVS Caremark, Scottsdale, AZ, ⁴Pediatrics, Seattle Childrens Hospital, Seattle, WA, ⁵Health Sciences Building, University of Washington, Seattle, WA
Background/Purpose: Medication adherence and persistence have been demonstrated to have important implications for treatment effectiveness, cost, and safety. Methotrexate is one of the most commonly…
Abstract Number: 1021 • 2012 ACR/ARHP Annual Meeting
Magnetic Resonance Imaging in Follow-up of Clinical Remission in Juvenile Idiopathic Arthritis
Mira van Veenendaal¹, Robert Hemke², Marjolein I. Bos³, Mario Maas⁴, Marion A. J. Van Rossum³ and Taco W. Kuijpers⁵, ¹Departments of Pediatric Rheumatology, Emma Children's Hospital / Academic Medical Center (AMC), Amsterdam, Netherlands, ²Departments of Radiology, Academic Medical Center (AMC), Amsterdam, Netherlands, ³Department of Pediatric Rheumatology and Immunology, Emma Children's Hospital / Academic Medical Center (AMC), Amsterdam, Netherlands, ⁴Radiology, Academic Medical Center, Amsterdam, Netherlands, ⁵Pediatric Rheumatology and Immunology, Emma Children's Hospital/Academic Medical Center (AMC), Amsterdam, Netherlands
Background/Purpose: Despite clinical remission, a substantial proportion of Juvenile Idiopathic Arthritis (JIA) patients will flare after a period of inactive disease. MRI has proven to…
Abstract Number: 2005 • 2012 ACR/ARHP Annual Meeting
Clinical Course and Outcomes of Children with Juvenile Idiopathic Arthritis-Associated Uveitis and Idiopathic Uveitis
Sheila T. Angeles-Han¹, Steven Yeh², Courtney McCracken³, Larry B. Vogler⁴, Kelly A. Rouster-Stevens⁵, Christine W. Kennedy⁶, Matthew Kent⁴, Kirsten Jenkins⁷, Scott Lambert⁸, Carolyn Drews-Botsch⁹ and Sampath Prahalad¹⁰, ¹Pediatrics, Emory Univ School of Medicine, Atlanta, GA, ²Ophthalmology, Emory University School of Medicine, Atlanta, GA, ³Emory University School of Medicine, Atlanta, GA, ⁴Dept of Pediatrics, Emory Univ School of Medicine, Atlanta, GA, ⁵Pediatric Rheumatologist, Emory Children's Center, Atlanta, GA, ⁶Rheumatology Immunology, Emory Children's Center, Atlanta, GA, ⁷Children's Healthcare of Atlanta, Atlanta, GA, ⁸Ophthalmology, Emory Univ School of Medicine, Atlanta, GA, ⁹Epidemiology, Emory University School of Public Health, Atlanta, GA, ¹⁰Pediatrics, Emory Children's Center, Atlanta, GA
Background/Purpose: Uveitis can lead to vision loss and blindness. Few studies focus on the outcomes of children with both juvenile idiopathic arthritis-associated uveitis (JIA-U) and…
Abstract Number: 974 • 2012 ACR/ARHP Annual Meeting
Identification of Susceptibility Loci for Inflammatory Arthritis
K. J. A. Steel¹, Anne Hinks², John Bowes³, Joanna Cobb², Edward Flynn⁴, Carl D. Langefeld⁵, Sampath Prahalad⁶, Johannes Peter Haas⁷, John F. Bohnsack⁸, Stephen Guthery⁸, Anne Barton¹, Susan D. Thompson⁹ and Wendy Thomson¹, ¹Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, United Kingdom, ²Arthritis Research UK Epidemiology Unit, Manchester Academic Health Sciences Centre, Institute of Inflammation and Repair, The University of Manchester, Manchester, United Kingdom, ³Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester, United Kingdom, ⁴Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester Academy of Health Sciences, Manchester, United Kingdom, ⁵Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC, ⁶Pediatrics, Emory Children's Center, Atlanta, GA, ⁷Childrens Hospital, Erlangen, Germany, ⁸Department of Pediatrics,, University of Utah, Salt Lake City, ⁹Department of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: One of the principal findings of genome wide association studies in autoimmune diseases has been the substantial overlap of genetic susceptibility loci identified. This…
Abstract Number: 2007 • 2012 ACR/ARHP Annual Meeting
Radiological Peripheral Involvement At Hands, Feet and Hips in Young Adults with Polyarticular Idiopathic Juvenile Arthritis
Muriel Elhai¹, Ramin Bazeli², Veronique Freire², Antoine Feydy², Andre Kahan³, Chantal Job-Deslandre⁴ and Julien Wipff¹, ¹Rheumatology A, Paris Descartes University, Cochin Hospital, APHP, Paris, France, ²Radiology B, Paris Descartes University, Cochin Hospital, APHP, Paris, France, ³Service de Rhumatologie A, Rheumatology A, Paris Descartes University, Cochin Hospital, APHP, Paris, France, ⁴Service de Rhumatologie, Rheumatology A, Paris Descartes University, Cochin Hospital, APHP, Paris, France
Background/Purpose: Radiographic damage was recently considered to be a feature of poor prognosis in cases of polyarticular juvenile idiopathic arthritis (pJIA). However, most radiographic studies…
Abstract Number: 760 • 2012 ACR/ARHP Annual Meeting
Catch-up Growth During Tocilizumab Therapy for Systemic Juvenile Idiopathic Arthritis: 2-Year Data From a Phase 3 Clinical Trial
Fabrizio De Benedetti¹, Nicolino Ruperto², Graciela Espada³, Valeria Gerloni⁴, Berit Flato⁵, Gerd Horneff⁶, Barry L. Myones⁷, Karen Onel⁸, James Frane⁹, Andrew Kenwright¹⁰, Terri H. Lipman¹¹, Kamal N. Bharucha⁹, Alberto Martini⁷ and D. J. Lovell¹², ¹Division of Rheumatology, Department of Pediatric Medicine, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy, ²Paediatric Rheumatology International Trials Organisation [PRINTO], Genova, Italy, ³Paediatric Rheumatology International Trials Organisation–IRCCS [PRINTO], Genova, Italy, ⁴Istituto Gaetano Pini, Milan, Italy, ⁵Department of Rheumatology, Oslo University Hospital, Rikshospitalet, Oslo, Norway, ⁶Department of Pediatrics, Centre of Pediatric Rheumatology, Sankt Augustin, Germany, ⁷Pediatric Rheumatology Collaborative Study Group [PRSCG], Cincinnati, OH, ⁸PRCSG, Cincinnati, OH, ⁹Genentech, South San Francisco, CA, ¹⁰Roche, Welwyn Garden City, United Kingdom, ¹¹University of Pennsylvania School of Nursing, Philadelphia, PA, ¹²Cincinnati Children's Hospital, Cincinnati, OH
Background/Purpose: Systemic juvenile idiopathic arthritis (sJIA), characterized by chronic arthritis associated with prominent systemic and laboratory features, also has a significant impact on the growing…
Abstract Number: 2011 • 2012 ACR/ARHP Annual Meeting
ACR Criteria, Providers’ Global Rating of Change and Role of Patient Self-Report in Evaluating Change in Disease Over Time: A Patient Reported Outcomes Measurement Information System Study
Bin Huang¹, Jennifer Farrell², Adam Carle³, Stacey Niehaus³, Hermine Brunner⁴, Alexei A. Grom⁵, Michael Henrickson⁶, Jennifer L. Huggins⁴, D. J. Lovell⁷, Tracy V. Ting⁴ and Esi M. Morgan DeWitt², ¹Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center/University of Cincinnati School of Medicine, Cincinnati, OH, ²Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁴Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁵PRCSG, Cincinnati, OH, ⁶MLC 4010, Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁷Cincinnati Children's Hospital, Cincinnati, OH
Background/Purpose: As part of a longitudinal study of Juvenile Idiopathic Arthritis (JIA), providers completed clinical outcomes assessments and patients (pt) completed self-report measures at clinic…
Abstract Number: 762 • 2012 ACR/ARHP Annual Meeting
Potentially Fatal Pulmonary Complications in Systemic Juvenile Idiopathic Arthritis
Yukiko Kimura¹, Jennifer E. Weiss², Kathryn L. Haroldson¹, Tzielan C. Lee³, Marilynn G. Punaro⁴, Sheila K. Feitosa de Oliveira⁵, C. Egla Rabinovich⁶, Meredith P. Riebschleger⁷, Jordi Anton⁸, Peter R. Blier⁹, Valeria Gerloni¹⁰, Melissa M. Hazen¹¹, Elizabeth Kessler¹², Karen Onel¹³, Murray H. Passo¹⁴, Robert M. Rennebohm¹⁵, Carol A. Wallace¹⁶, Patricia Woo¹⁷, Nico M. Wulffraat¹⁸ and CARRAnet Investigators¹⁹, ¹Pediatric Rheumatology, JM Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack, NJ, ²Pediatric Rheumatology, Joseph M Sanzari Children’s Hospital, Hackensack University Medical Center, Hackensack, NJ, ³Pediatric Rheumatology, Stanford University School of Medicine, Stanford, CA, ⁴Pediatric Rheumatology, Texas Scottish Rite Hospital, Dallas, TX, ⁵Pediatric Rheumatology, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil, ⁶Pediatric Rheumatology, Duke University Medical Center, Durham, NC, ⁷Pediatric Rheumatology & Health Services Research, University of Michigan, Ann Arbor, MI, ⁸Rheumatology, Hospital Sant Joan de Deu, Barcelona, Spain, ⁹Pediatrics, Baystate Children's Hospital, Springfield, MA, ¹⁰Pediatric Rheumatology, Gaetano Pini Chair of Rheum, Milan, Italy, ¹¹Division of Immunology, Boston Children's Hospital, Boston, MA, ¹²Pediatric Rheumatology, Medical College of Wisconsin, Milwaukee, WI, ¹³Pediatric Rheumatology, University of Chicago Hospitals, Chicago, IL, ¹⁴Pediatrics, Medical University of South Carolina, Charleston, SC, ¹⁵Pediatric Rheumatology, Alberta Children's Hospital, University of Calgary, Calgary, AB, Canada, ¹⁶Pediatrics, Seattle Childrens Hospital, Seattle, WA, ¹⁷Division of Infection and Immunity, University College London, London, United Kingdom, ¹⁸Pediatric Immunology, University Medical Center Utrecht, Utrecht, Netherlands, ¹⁹Durham
Background/Purpose: Systemic Juvenile Idiopathic Arthritis (sJIA) is characterized by fevers, rash and arthritis, for which IL1 and IL6 inhibitors appear to be effective. Pulmonary artery…

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