Abstracts tagged "juvenile idiopathic arthritis (JIA)"

Abstract Number: 1157 • 2012 ACR/ARHP Annual Meeting
The Phenotypic Characterization of Juvenile Idiopathic Arthritis in African American Children
Lauren Minor¹, Lori Ponder², Emily G. Ferrell³, Sheila Angeles-Han¹, Christine W. Kennedy⁴, Kelly A. Rouster-Stevens¹, Mina Pichavant¹, Larry B. Vogler³ and Sampath Prahalad¹, ¹Pediatrics, Emory University School of Medicine, Atlanta, GA, ²Children's Healthcare of Atlanta, Atlanta, GA, ³Emory University School of Medicine, Atlanta, GA, ⁴Rheumatology Immunology, Emory Children's Center, Atlanta, GA
Background/Purpose: JIA, a common childhood arthropathy, with an estimated prevalence of 1 in 1000 in children under the age of 16, affects children of all…
Abstract Number: 2657 • 2012 ACR/ARHP Annual Meeting
Genome-Wide Association Meta-Analysis of Eight Independent Systemic Juvenile Idiopathic Arthritis Collections Reveals Regional Association Spanning the Major Histocompatibility Complex Class II and III Gene Cluster
Michael J. Ombrello¹, Elaine Remmers², Alexei A. Grom³, Wendy Thomson⁴, Alberto Martini⁵, Marco Gattorno⁶, Seza Ozen⁷, Sampath Prahalad⁸, John F. Bohnsack⁹, Andrew Zeft¹⁰, Norman T. Ilowite¹¹, Elizabeth D. Mellins¹², Ricardo A. G. Russo¹³, Claudio Len¹⁴, Sheila K. Oliveira¹⁵, Rae SM Yeung¹⁶, Lucy R. Wedderburn¹⁷, Jordi Anton Lopez¹⁸, Colleen Satorius¹⁹, Ioanna Tachmazidou²⁰, Carl D. Langefeld²¹, Eleftheria Zeggini²⁰, Susan D. Thompson²², Patricia Woo²³ and Daniel L. Kastner², ¹Translational Genetics and Genomics Unit, National Institute of Arthritis Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ²Inflammatory Disease Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, ³PRCSG, Cincinnati, OH, ⁴Manchester Academic Health Science Centre, Arthritis Research UK Epidemiology Unit, Manchester, United Kingdom, ⁵Pediatric Rheumatology Collaborative Study Group [PRSCG], Cincinnati, OH, ⁶Second Division of Paediatrics, Istituto Giannina Gaslini, Genova, Italy, ⁷Hacettepe University, Ankara, Turkey, ⁸Pediatrics, Emory Children's Center, Atlanta, GA, ⁹Dept of Pediatriacs, University of Utah, Salt Lake City, UT, ¹⁰Pediatric Rheumatology, The Cleveland Clinic, Cleveland, OH, ¹¹Pediatrics, The Children's Hospital at Montefiore, Bronx, NY, ¹²Dept of Pediatrics CCSR, Stanford University Medical Center, Stanford, CA, ¹³Immunology & Rheumatology, Hospital de Pediatria Garrahan, Buenos Aires, Argentina, ¹⁴Pediatrics, Universidade Federal de São Paulo / UNIFESP, Sao Paulo, Brazil, ¹⁵Pediatric Rheumatology, Instituto de Pediatria e Puericultura Martagão Gesteira (IPPMG) da Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil, ¹⁶Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, ¹⁷Rheumatology Unit , Institute of Child Health, University College London (UCL), London, United Kingdom, ¹⁸pediatric Rheumatology, University Childrenxs Hospital, Barcelona, Spain, ¹⁹Inflammatory Disease Section, National Human Genome Research Institute, Nationsl Institutes of Health, Bethesda, MD, ²⁰The Wellcome Trust Sanger Institute, Cambridge, United Kingdom, ²¹Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC, ²²Department of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²³Division of Infection and Immunity, University College London, London, United Kingdom
Background/Purpose: Systemic juvenile idiopathic arthritis (sJIA) is a rare inflammatory disease that is inherited as a complex genetic trait. While the pathophysiology of sJIA is…
Abstract Number: 1160 • 2012 ACR/ARHP Annual Meeting
Assessment of Subclinical Synovitis by Power Doppler Ultrasonography in Patients with Juvenile Idiopathic Arthritis
Maria Teresa Terreri¹, Vanessa M. Bugni², Claudio A. Len², Sônia de A.V. Mitraud³, Rita NV. Furtado⁴ and Jamil Natour⁵, ¹Pediatrics, Universidade Federal de São Paulo / UNIFESP, Sao Paulo, Brazil, ²Pediatrics, Universidade Federal de São Paulo / UNIFESP, São Paulo, Brazil, ³Radiology and Diagnostic Imaging, Escola Paulista de Medicina/ Universidade Federal de São Paulo (EPM/UNIFESP), São Paulo, Brazil, ⁴Rheumatology, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, ⁵Rheumatology Division, Universidade Federal de São Paulo, São Paulo, Brazil
Background/Purpose: Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in childhood, leading to physical disability and poor quality of life. Advances in…
Abstract Number: 1162 • 2012 ACR/ARHP Annual Meeting
Patients with Juvenile Idiopathic Arthritis From a Low Socio-Economic Background Perceive Their Disease Activity and Physical Limitations Higher Than Patients from a High Socio-Economic Background
Suzanne Verstappen¹, Joanna Cobb², H. E. Foster³, Eileen Baildam⁴, Lucy R. Wedderburn⁵, Janet Gardner-Medwin⁶, Alice Chieng⁷, Joyce Davidson⁶, Wendy Thomson⁸ and Kimme L. Hyrich⁹, ¹Arthritis Research UK Epidemiology Unit,, University of Manchester, Manchester Academic Health Sciences Centre, Manchester, United Kingdom, ²Manchester Academic Health Science Centre, Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, United Kingdom, ³Paediatric Rheumatology, Newcastle Hospitals NHS Foundation Trust and Great North Children's Hospital, Newcastle Upon Tyne, United Kingdom, ⁴Paediatric Rheumatology, Alder Hey Children's Foundation NHS Trust, Liverpool, United Kingdom, ⁵Rheumatology Unit , Institute of Child Health, University College London (UCL), London, United Kingdom, ⁶Royal Hospital for Sick Children, Glasgow, United Kingdom, ⁷Manchester Children's Hospital, Manchester, United Kingdom, ⁸Manchester Academic Health Science Centre, Arthritis Research UK Epidemiology Unit, Manchester, United Kingdom, ⁹Centre for Musculoskeletal Research, University of Manchester, Manchester, United Kingdom
Background/Purpose: It has been suggested that socio-economic status (SES) may be associated with delayed to access to rheumatology care and with worse disease severity…
Abstract Number: 1164 • 2012 ACR/ARHP Annual Meeting
Orofacial Anomalies in Children with Confirmed Juvenile Idiopathic Arthritis
Bernd Koos¹, Franka Stahl de Castrillon², Robert Ciesielski¹ and Nikolay Tzaribachev³, ¹Clinic of Orthodontics, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany, ²Department of Orthodontics, University of Rostock, Germany, Department of Orthodontics, University of Rostock, Germany, Rostock, Germany, ³Pediatric Rheumatology, Center for Rheumatic Diseases, Bad Bramstedt, Germany
Background/Purpose: In children with juvenile idiopathic arthritis (JIA) temporomandibular joints (TMJ) are affected in up to 96% of the patients, where TMJ arthritis is frequently…
Abstract Number: 2601 • 2012 ACR/ARHP Annual Meeting
Improving Delivery of Care for JIA Across a Multi-Center Network Using a Shared Data Registry and Quality Improvement Science: The Pediatric Rheumatology Care and Outcomes Improvement Network
Catherine A. Bingham¹, Lynn M. Darbie², Keith Marsolo³, Jennifer E. Weiss⁴, Stacy P. Ardoin⁵, Ronald Laxer⁶, D. J. Lovell⁷, Murray H. Passo⁸, Sheetal Vora⁹, Beth S. Gottlieb¹⁰, Timothy Beukelman¹¹, Nancy Griffin², Jason A. Stock¹², Michael L. Miller¹³, Karen Onel¹⁴, Tova Ronis¹⁵, Peter Margolis¹⁶ and Esi M. Morgan DeWitt¹⁷, ¹Pediatric Rheumatology, Penn State Hershey Children's Hospital, Hershey, PA, ²James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Division of Biomedical Informatics, Cincinnati Children's Hospital, Cincinnati, OH, ⁴Pediatric Rheumatology, Hackensack University Medical Center, Hackensack, NJ, ⁵Pediatric & Adult Rheumatology, Ohio State University College of Medicine, Columbus, OH, ⁶Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ⁷Cincinnati Children's Hospital, Cincinnati, OH, ⁸Pediatric Rheumatology, Medical University of South Carolina, Charleston, SC, ⁹Pediatric Rheumatology, Medical College of Wisconsin, Milwaukee, WI, ¹⁰Pediatric Rheumatology, Cohen Children's Medical Center of New York, New Hyde Park, NY, ¹¹Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ¹²Biostatistics & Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ¹³Rheumatology, Childrens Memorial Hospital, Chicago, IL, ¹⁴Pediatric Rheumatology, University of Chicago, Chicago, IL, ¹⁵Pediatric Rheumatology, Stanford University Hospital, Palo Alto, CA, ¹⁶Clinical Effectiveness, Cincinnati Children's Hospital, Cincinnati, OH, ¹⁷Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: The Pediatric Rheumatology Care and Outcomes Improvement Network (PR-COIN) is a quality improvement (QI) multi-center “learning network” that performs QI and research while tracking…
Abstract Number: 1173 • 2012 ACR/ARHP Annual Meeting
Targeting Remission in Juvenile Idiopathic Arthritis in Routine Clinical Care: Experience in 175 Newly-Diagnosed Patients
Alessandro Consolaro¹, Giorgia Negro¹, Nicoletta Solari¹, Cristina Ferrari¹, Sergio Davì¹, Silvia Pederzoli¹, Giulia Bracciolini¹, Maria C. Gallo¹, Alberto Martini² and Angelo Ravelli³, ¹Pediatria II, Istituto Giannina Gaslini, Genova, Italy, ²Pediatric Rheumatology Collaborative Study Group [PRSCG], Cincinnati, OH, ³Paediatric Rheumatology International Trials Organization (PRINTO), Istituto Giannina Gaslini, Genova, Italy
Background/Purpose: The recent advances in the management of juvenile idiopathic arthritis (JIA) have increased considerably the potential to achieve disease remission or, at least, low…
Abstract Number: 2042 • 2012 ACR/ARHP Annual Meeting
Enhancing Shared Decision-Making in Juvenile Idiopathic Arthritis
Jessica M. Sage¹, Ellen A. Lipstein², William B. Brinkman³, Carole M. Lannon⁴ and Esi M. Morgan DeWitt⁵, ¹Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Division of Adolescent Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁴James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁵Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: Juvenile idiopathic arthritis (JIA) is a chronic disease that requires long-term treatment. Patients and families face multiple treatment decisions over the course of illness…
Abstract Number: 1141 • 2012 ACR/ARHP Annual Meeting
Safety of Celecoxib and Non-Selective Non-Steroidal Anti-Inflammatory Drugs in Juvenile Idiopathic Arthritis
Rachel E. Sobel¹, D. J. Lovell², Hermine Brunner³, Jennifer E. Weiss⁴, Paula W. Morris⁵, Beth S. Gottlieb⁶, Elizabeth C. Chalom⁷, Lawrence K. Jung⁸, Karen Onel⁹, Lisa Petinoit¹⁰, Donald P. Goldsmith¹¹, Staci Abramsky-Risman¹², James P., Young¹³ and Edward H. Giannini¹⁴, ¹Epidemiology, Worldwide Safety Strategy, Pfizer, Inc., New York, NY, ²Cincinnati Children's Hospital, Cincinnati, OH, ³Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁴Pediatric Rheumatology, Hackensack Univ Med Ctr, Hackensack, NJ, ⁵Pediatrics, Univ of Arkansas for Med Sci, Little Rock, AR, ⁶Pediatric Rheumatology, Cohen Children's Medical Center of New York, New Hyde Park, NY, ⁷Pediatrics, St. Barnabas Medical Center, Livingston, NJ, ⁸Pediatric Rheumatology, Children's National Medical Center, Washington, DC, ⁹Pediatric Rheumatology, University of Chicago Hospitals, Chicago, IL, ¹⁰Pediatric Rheumatology, 'Specially for Children, Dell Children's Medical Center, Austin, TX, ¹¹Pediatric Rheumaology, St Christopher's Hospital for Children/ Drexel College of Medicine, Philadelphia, PA, ¹²Pfizer Inc, New York, NY, ¹³United BioSource Corporation, Ann Arbor, MI, ¹⁴Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: Celecoxib, a selective COX-2 inhibitor, was approved by the FDA for the treatment of the signs and symptoms of JIA in children aged 2-17…
Abstract Number: 2026 • 2012 ACR/ARHP Annual Meeting
High Prevalence of Cervical Spine and Temporomandibular Joint Involvement in Patients with Juvenile Idiopathic Arthritis
Nikolay Tzaribachev¹, Catrin Tzaribachev¹ and Bernd Koos², ¹Pediatric Rheumatology, Center for Rheumatic Diseases, Bad Bramstedt, Germany, ²Clinic of Orthodontics, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany
Background/Purpose: Detection of involvement of temporomandibular joints (TMJ), which are frequently affected by juvenile idiopathic arthritis (JIA), is only possible on Gadolinium enhanced MRI…
Abstract Number: 1155 • 2012 ACR/ARHP Annual Meeting
A New Measure of Visual Function for Children with Juvenile Idiopathic Arthritis-Associated Uveitis
Sheila T. Angeles-Han¹, Steven Yeh², Courtney McCracken¹, Larry B. Vogler³, Kelly A. Rouster-Stevens⁴, Christine W. Kennedy⁵, Kirsten Jenkins⁶, Matthew Kent³, Scott Lambert⁷, Carolyn Drews-Botsch⁸ and Sampath Prahalad⁹, ¹Emory University School of Medicine, Atlanta, GA, ²Ophthalmology, Emory University School of Medicine, Atlanta, GA, ³Dept of Pediatrics, Emory Univ School of Medicine, Atlanta, GA, ⁴Pediatric Rheumatology, Emory Univ School of Medicine, Atlanta, GA, ⁵Rheumatology Immunology, Emory Children's Center, Atlanta, GA, ⁶Children's Healthcare of Atlanta, Atlanta, GA, ⁷Ophthalmology, Emory Univ School of Medicine, Atlanta, GA, ⁸Epidemiology, Emory University School of Public Health, Atlanta, GA, ⁹Pediatrics, Emory Children's Center, Atlanta, GA
Background/Purpose: Studies on outcomes of children with juvenile idiopathic arthritis-associated uveitis (JIA-U) focus on the clinical ocular exam and physical disability secondary to arthritis. This…

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