Abstracts tagged "juvenile idiopathic arthritis (JIA)"

Abstract Number: 339 • 2012 ACR/ARHP Annual Meeting
Differences Between Juvenile and Adult Rodents with Collagen Induced Arthritis
Tracy D. Wilson-Gerwing¹, Isaac V. Pratt², David M.L. Cooper², Tawni I. Silver³ and Alan M. Rosenberg⁴, ¹Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada, ²Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, SK, Canada, ³Small Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada, ⁴Department of Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada
Background/Purpose: Juvenile idiopathic arthritis (JIA) is among the most common chronic diseases of childhood. Arthritis is a potentially disabling disease that can result in ongoing…
Abstract Number: 1837 • 2012 ACR/ARHP Annual Meeting
Which Rheumatoid Arthritis, Ankylosing Spondylitis and Juvenile Idiopathic Arthritis Patients Initiate Anti-TNFá Therapy?
Alain Saraux¹, Jacques Benichou², Chantal Deslandre³, Loic Guillevin⁴, Latifa Idbrik⁵, Jean Sibilia⁶, Marc Soudan⁵, Daniel Wendling⁷ and Francis Guillemin⁸, ¹Rheumatology, CHU de la Cavale Blanche and Université Bretagne occidentale, Brest Cedex, France, ²INSERM U657 Pharmacoepidemiology and evaluation of the impact of health products on human health, France, and Department of Biostatistics, University Hospital of Rouen, Rouen, France, EA4438 Laboratoire Physiopathologie des Arthrites, Rouen, France, ³Rheumatology, Cochin Hospital, Paris, France, ⁴Internal Medicine, Division of Internal Medicine, Hôpital Cochin, University Paris Descartes, Paris, France, ⁵Ecole de Sante Publique, Faculte de Medecin/BP 184, Vandoeuvre-les-Nancy, France, ⁶Université de Strasbourg, EA4438 Laboratoire Physiopathologie des Arthrites, Illkirch-Strasbourg, France, ⁷Service de Rhumatologie, Minjoz University Hospital, Besancon, France, ⁸Hopitaux de Brabois, Nancy, France
Background/Purpose: Comprehensive guidelines for anti-TNFα were proposed in 2005 by the French Society for Rheumatology (SFR) in France; they did not include any economic considerations…
Abstract Number: 317 • 2012 ACR/ARHP Annual Meeting
Fatty Acid Profiling: Potential New Biomarkers in Juvenile Idiopathic Arthritis (pilot study)
Weng Tarng Cham¹, Enzo Ranieri², Janice Fletcher² and Christina A. Boros³, ¹Paediatric Rheumatology, Women's and Children's Hospital, North Adelaide, SA 5006, Australia, ²Chemical Pathology and Molecular Genetics, SA Pathology, North Adelaide, SA 5006, Australia, ³Paediatrics, University of Adelaide/Women's and Children's Hospital, Adelaide, Australia
Background/Purpose: The prostanoids are a family of biologically active lipids derived from the 20-carbon essential fatty acids (LCPUFA) all of which are involved in the…
Abstract Number: 1644 • 2012 ACR/ARHP Annual Meeting
Enhanced Pharmacovigilance Reporting of Malignancies in Children and Young Adults Taking Etanercept
Michele Hooper¹, Deborah Wenkert², Bojena Bitman³, Virgil C. Dias⁴, Yessinia Bartley⁵, Julie Wang⁶ and Julia R. Gage⁷, ¹Amgen Global Safety, Amgen Inc., Thousand Oaks, CA, ²Inflammation TA, Amgen Inc., Thousand Oaks, CA, ³Amgen, Inc., San Francisco, CA, ⁴Amgen Inc., Thousand Oaks, CA, ⁵Assent Consulting, Solana Beach, CA, ⁶Amgen Inc, One Amgen Center Drive, Thousand Oaks, CA, ⁷Gage Medical Writing, LLC, Oak Park, CA
Background/Purpose: Recent reports suggest an increased rate of malignancy in children with juvenile idiopathic arthritis (JIA) (Simard, A&R 2010;62:3776; Beukelman A&R 2012;64:1263). In 2011, the…
Abstract Number: 321 • 2012 ACR/ARHP Annual Meeting
Glycosylation of Vitamin D Binding Protein Reduced in Juvenile Idiopathic Arthritis Patients At Risk of Disease Extension
David S. Gibson¹, Sorcha Finnegan², Gwen Manning³, Mark Duncan⁴, Stephen R. Pennington⁵, Terry L. Moore⁶ and Madeleine Rooney⁷, ¹Centre for Infection and immunity, Arthritis Research Group, Queens University Belfast, Belfast, United Kingdom, ²Centre for Infection and Immunity, Queen's University, Belfast, Belfast, United Kingdom, ³Proteome Research Centre, University College Dublin, Dublin, Ireland, ⁴Division of Endocrinology, University of Colorado, Denver, ⁵UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland, ⁶Internal Medicine/Rheumatology, Saint Louis University, Saint Louis, MO, ⁷Medicine, Queens University Belfast, Belfast, United Kingdom
Background/Purpose: Juvenile idiopathic arthritis (JIA) comprises a poorly understood group of chronic, childhood onset, autoimmune diseases with variable clinical outcomes.We investigated whether profiling of the…
Abstract Number: 1597 • 2012 ACR/ARHP Annual Meeting
Efficacy and Safety of Tocilizumab in Patients with Polyarticular Juvenile Idiopathic Arthritis: Data From a Phase 3 Trial
Hermine Brunner¹, Nicolino Ruperto², Zbigniew Zuber³, Caroline Keane⁴, Olivier Harari⁵, Andrew Kenwright⁴, Rubén J. Cuttica⁶, Vladimir Keltsev⁷, Ricardo Xavier³, Inmaculada Calvo Penades⁷, Irina Nikishina⁸, Nadina Rubio-Perez⁹, Ekaterina Alekseeva¹⁰, Vyacheslav Chasnyk¹¹, Jose Chavez³, Gerd Horneff¹², Violetta Opoka-Winiarska³, Pierre Quartier¹³, Clovis A. Silva⁷, Earl D. Silverman¹⁴, Alberto Spindler¹⁴, D. J. Lovell¹⁵, Alberto Martini¹⁴ and Fabrizio De Benedetti¹⁶, ¹Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Paediatric Rheumatology International Trials Organisation [PRINTO], Genova, Italy, ³PRINTO, Genoa, Italy, ⁴Roche, Welwyn Garden City, United Kingdom, ⁵Roche Products Ltd., Welwyn Garden City, United Kingdom, ⁶Hospital de Niños Pedro de Elizalde - University of Buenos Aires, Buenes Aires, Argentina, ⁷Paediatric Rheumatology International Trials Organisation–IRCCS [PRINTO], Genoa, Italy, ⁸Pediatric Department, Scientific Research Institute of Rheumatology RAMS, Moskow, Moskow, Russia, ⁹Hospital Universitario Dr. José Eleuterio Gonzalez, Monterrey, Mexico, ¹⁰Istituto Giannina Gaslini, Genoa, Italy, ¹¹Hospital Pediatry, State Pediatric Medical University, Saint-Petersburg, Russia, ¹²Department of Pediatrics, Centre of Pediatric Rheumatology, Sankt Augustin, Germany, ¹³Pediatria II, Istituto Giannina Gaslini, Genoa, Italy, ¹⁴Pediatric Rheumatology Collaborative Study Group [PRSCG], Cincinnati, OH, ¹⁵Cincinnati Children's Hospital, Cincinnati, OH, ¹⁶PRINTO and PRSCG, Genoa, Italy
Background/Purpose: Elevated IL-6 levels are associated with disease activity in patients (pts) with juvenile idiopathic arthritis (JIA).1 Tocilizumab (TCZ), an IL-6 receptor inhibitor, was evaluated…
Abstract Number: 123 • 2012 ACR/ARHP Annual Meeting
Detection of Synovitis in Clinically Inactive Juvenile Idiopathic Arthritis Patients by Ultrasonography with POWER Doppler
Paz Collado¹, MariLuz Gamir², Rosa Merino³, Consuelo Modesto⁴, Indalecio Monteagudo⁵ and Juan Carlos Lopez-Robledillo⁶, ¹Rheumatology, Severo Ochoa University Hospital, Madrid, Spain, ²Rheumatology, Ramon y Cajal University Hospital, Madrid, Spain, ³Hospital Universitario La Paz, Madrid, Spain, ⁴Hospital Valle de Hebron, Barcelona, Spain, ⁵Rheumatology, Gregorio Marañón Hospital, Madrid, Spain, ⁶Hospital Niño Jesus, Madrid, Spain
Background/Purpose: The advances in therapeutic effectiveness have created a need for looking for imaging tools that describe more precisely the clinical state of disease inactivity.…
Abstract Number: 1157 • 2012 ACR/ARHP Annual Meeting
The Phenotypic Characterization of Juvenile Idiopathic Arthritis in African American Children
Lauren Minor¹, Lori Ponder², Emily G. Ferrell³, Sheila Angeles-Han¹, Christine W. Kennedy⁴, Kelly A. Rouster-Stevens¹, Mina Pichavant¹, Larry B. Vogler³ and Sampath Prahalad¹, ¹Pediatrics, Emory University School of Medicine, Atlanta, GA, ²Children's Healthcare of Atlanta, Atlanta, GA, ³Emory University School of Medicine, Atlanta, GA, ⁴Rheumatology Immunology, Emory Children's Center, Atlanta, GA
Background/Purpose: JIA, a common childhood arthropathy, with an estimated prevalence of 1 in 1000 in children under the age of 16, affects children of all…
Abstract Number: 2657 • 2012 ACR/ARHP Annual Meeting
Genome-Wide Association Meta-Analysis of Eight Independent Systemic Juvenile Idiopathic Arthritis Collections Reveals Regional Association Spanning the Major Histocompatibility Complex Class II and III Gene Cluster
Michael J. Ombrello¹, Elaine Remmers², Alexei A. Grom³, Wendy Thomson⁴, Alberto Martini⁵, Marco Gattorno⁶, Seza Ozen⁷, Sampath Prahalad⁸, John F. Bohnsack⁹, Andrew Zeft¹⁰, Norman T. Ilowite¹¹, Elizabeth D. Mellins¹², Ricardo A. G. Russo¹³, Claudio Len¹⁴, Sheila K. Oliveira¹⁵, Rae SM Yeung¹⁶, Lucy R. Wedderburn¹⁷, Jordi Anton Lopez¹⁸, Colleen Satorius¹⁹, Ioanna Tachmazidou²⁰, Carl D. Langefeld²¹, Eleftheria Zeggini²⁰, Susan D. Thompson²², Patricia Woo²³ and Daniel L. Kastner², ¹Translational Genetics and Genomics Unit, National Institute of Arthritis Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ²Inflammatory Disease Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, ³PRCSG, Cincinnati, OH, ⁴Manchester Academic Health Science Centre, Arthritis Research UK Epidemiology Unit, Manchester, United Kingdom, ⁵Pediatric Rheumatology Collaborative Study Group [PRSCG], Cincinnati, OH, ⁶Second Division of Paediatrics, Istituto Giannina Gaslini, Genova, Italy, ⁷Hacettepe University, Ankara, Turkey, ⁸Pediatrics, Emory Children's Center, Atlanta, GA, ⁹Dept of Pediatriacs, University of Utah, Salt Lake City, UT, ¹⁰Pediatric Rheumatology, The Cleveland Clinic, Cleveland, OH, ¹¹Pediatrics, The Children's Hospital at Montefiore, Bronx, NY, ¹²Dept of Pediatrics CCSR, Stanford University Medical Center, Stanford, CA, ¹³Immunology & Rheumatology, Hospital de Pediatria Garrahan, Buenos Aires, Argentina, ¹⁴Pediatrics, Universidade Federal de São Paulo / UNIFESP, Sao Paulo, Brazil, ¹⁵Pediatric Rheumatology, Instituto de Pediatria e Puericultura Martagão Gesteira (IPPMG) da Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil, ¹⁶Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, ¹⁷Rheumatology Unit , Institute of Child Health, University College London (UCL), London, United Kingdom, ¹⁸pediatric Rheumatology, University Childrenxs Hospital, Barcelona, Spain, ¹⁹Inflammatory Disease Section, National Human Genome Research Institute, Nationsl Institutes of Health, Bethesda, MD, ²⁰The Wellcome Trust Sanger Institute, Cambridge, United Kingdom, ²¹Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC, ²²Department of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²³Division of Infection and Immunity, University College London, London, United Kingdom
Background/Purpose: Systemic juvenile idiopathic arthritis (sJIA) is a rare inflammatory disease that is inherited as a complex genetic trait. While the pathophysiology of sJIA is…
Abstract Number: 1160 • 2012 ACR/ARHP Annual Meeting
Assessment of Subclinical Synovitis by Power Doppler Ultrasonography in Patients with Juvenile Idiopathic Arthritis
Maria Teresa Terreri¹, Vanessa M. Bugni², Claudio A. Len², Sônia de A.V. Mitraud³, Rita NV. Furtado⁴ and Jamil Natour⁵, ¹Pediatrics, Universidade Federal de São Paulo / UNIFESP, Sao Paulo, Brazil, ²Pediatrics, Universidade Federal de São Paulo / UNIFESP, São Paulo, Brazil, ³Radiology and Diagnostic Imaging, Escola Paulista de Medicina/ Universidade Federal de São Paulo (EPM/UNIFESP), São Paulo, Brazil, ⁴Rheumatology, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, ⁵Rheumatology Division, Universidade Federal de São Paulo, São Paulo, Brazil
Background/Purpose: Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in childhood, leading to physical disability and poor quality of life. Advances in…
Abstract Number: 1162 • 2012 ACR/ARHP Annual Meeting
Patients with Juvenile Idiopathic Arthritis From a Low Socio-Economic Background Perceive Their Disease Activity and Physical Limitations Higher Than Patients from a High Socio-Economic Background
Suzanne Verstappen¹, Joanna Cobb², H. E. Foster³, Eileen Baildam⁴, Lucy R. Wedderburn⁵, Janet Gardner-Medwin⁶, Alice Chieng⁷, Joyce Davidson⁶, Wendy Thomson⁸ and Kimme L. Hyrich⁹, ¹Arthritis Research UK Epidemiology Unit,, University of Manchester, Manchester Academic Health Sciences Centre, Manchester, United Kingdom, ²Manchester Academic Health Science Centre, Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, United Kingdom, ³Paediatric Rheumatology, Newcastle Hospitals NHS Foundation Trust and Great North Children's Hospital, Newcastle Upon Tyne, United Kingdom, ⁴Paediatric Rheumatology, Alder Hey Children's Foundation NHS Trust, Liverpool, United Kingdom, ⁵Rheumatology Unit , Institute of Child Health, University College London (UCL), London, United Kingdom, ⁶Royal Hospital for Sick Children, Glasgow, United Kingdom, ⁷Manchester Children's Hospital, Manchester, United Kingdom, ⁸Manchester Academic Health Science Centre, Arthritis Research UK Epidemiology Unit, Manchester, United Kingdom, ⁹Centre for Musculoskeletal Research, University of Manchester, Manchester, United Kingdom
Background/Purpose: It has been suggested that socio-economic status (SES) may be associated with delayed to access to rheumatology care and with worse disease severity…
Abstract Number: 1164 • 2012 ACR/ARHP Annual Meeting
Orofacial Anomalies in Children with Confirmed Juvenile Idiopathic Arthritis
Bernd Koos¹, Franka Stahl de Castrillon², Robert Ciesielski¹ and Nikolay Tzaribachev³, ¹Clinic of Orthodontics, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany, ²Department of Orthodontics, University of Rostock, Germany, Department of Orthodontics, University of Rostock, Germany, Rostock, Germany, ³Pediatric Rheumatology, Center for Rheumatic Diseases, Bad Bramstedt, Germany
Background/Purpose: In children with juvenile idiopathic arthritis (JIA) temporomandibular joints (TMJ) are affected in up to 96% of the patients, where TMJ arthritis is frequently…
Abstract Number: 2601 • 2012 ACR/ARHP Annual Meeting
Improving Delivery of Care for JIA Across a Multi-Center Network Using a Shared Data Registry and Quality Improvement Science: The Pediatric Rheumatology Care and Outcomes Improvement Network
Catherine A. Bingham¹, Lynn M. Darbie², Keith Marsolo³, Jennifer E. Weiss⁴, Stacy P. Ardoin⁵, Ronald Laxer⁶, D. J. Lovell⁷, Murray H. Passo⁸, Sheetal Vora⁹, Beth S. Gottlieb¹⁰, Timothy Beukelman¹¹, Nancy Griffin², Jason A. Stock¹², Michael L. Miller¹³, Karen Onel¹⁴, Tova Ronis¹⁵, Peter Margolis¹⁶ and Esi M. Morgan DeWitt¹⁷, ¹Pediatric Rheumatology, Penn State Hershey Children's Hospital, Hershey, PA, ²James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Division of Biomedical Informatics, Cincinnati Children's Hospital, Cincinnati, OH, ⁴Pediatric Rheumatology, Hackensack University Medical Center, Hackensack, NJ, ⁵Pediatric & Adult Rheumatology, Ohio State University College of Medicine, Columbus, OH, ⁶Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ⁷Cincinnati Children's Hospital, Cincinnati, OH, ⁸Pediatric Rheumatology, Medical University of South Carolina, Charleston, SC, ⁹Pediatric Rheumatology, Medical College of Wisconsin, Milwaukee, WI, ¹⁰Pediatric Rheumatology, Cohen Children's Medical Center of New York, New Hyde Park, NY, ¹¹Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ¹²Biostatistics & Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ¹³Rheumatology, Childrens Memorial Hospital, Chicago, IL, ¹⁴Pediatric Rheumatology, University of Chicago, Chicago, IL, ¹⁵Pediatric Rheumatology, Stanford University Hospital, Palo Alto, CA, ¹⁶Clinical Effectiveness, Cincinnati Children's Hospital, Cincinnati, OH, ¹⁷Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: The Pediatric Rheumatology Care and Outcomes Improvement Network (PR-COIN) is a quality improvement (QI) multi-center “learning network” that performs QI and research while tracking…
Abstract Number: 1173 • 2012 ACR/ARHP Annual Meeting
Targeting Remission in Juvenile Idiopathic Arthritis in Routine Clinical Care: Experience in 175 Newly-Diagnosed Patients
Alessandro Consolaro¹, Giorgia Negro¹, Nicoletta Solari¹, Cristina Ferrari¹, Sergio Davì¹, Silvia Pederzoli¹, Giulia Bracciolini¹, Maria C. Gallo¹, Alberto Martini² and Angelo Ravelli³, ¹Pediatria II, Istituto Giannina Gaslini, Genova, Italy, ²Pediatric Rheumatology Collaborative Study Group [PRSCG], Cincinnati, OH, ³Paediatric Rheumatology International Trials Organization (PRINTO), Istituto Giannina Gaslini, Genova, Italy
Background/Purpose: The recent advances in the management of juvenile idiopathic arthritis (JIA) have increased considerably the potential to achieve disease remission or, at least, low…
Abstract Number: 2042 • 2012 ACR/ARHP Annual Meeting
Enhancing Shared Decision-Making in Juvenile Idiopathic Arthritis
Jessica M. Sage¹, Ellen A. Lipstein², William B. Brinkman³, Carole M. Lannon⁴ and Esi M. Morgan DeWitt⁵, ¹Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Division of Adolescent Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁴James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁵Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: Juvenile idiopathic arthritis (JIA) is a chronic disease that requires long-term treatment. Patients and families face multiple treatment decisions over the course of illness…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].