Abstracts tagged "juvenile idiopathic arthritis (JIA)"

Abstract Number: 3147 • 2015 ACR/ARHP Annual Meeting
Inter-Provider Reliability in Scoring the Physician Global Assessment of Disease Activity Among Patients with Juvenile Idiopathic Arthritis Patients Who Met the ACR Provisional Criteria for Clinical Inactive Disease
Janalee Taylor¹, Edward H. Giannini¹, Daniel Lovell² and Esi M. Morgan DeWitt¹, ¹Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²PRCSG, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
Background/Purpose: With the advent and implementation of advanced drug therapy clinical inactive disease (CID) has become an attainable target in the treatment of juvenile idiopathic…
Abstract Number: 1463 • 2015 ACR/ARHP Annual Meeting
Anti-Cyclic Citrullinated Peptide Antibody Subclass Phenotypes in Polyarticular Juvenile Idiopathic Arthritis
Hannah Peckham¹, Lauren Bourke^2,3, Anna Radziszewska⁴, Maria Leandro⁵, Debajit Sen², Geraldine Cambridge⁶ and Yiannis Ioannou^7,8, ¹Adolescent Centre for Rheumatology Research, University College London, London, United Kingdom, ²Arthritis Research UK Centre for Adolescent Rheumatology, University College London, London, United Kingdom, ³Centre for Rheumatology Research, University College London, London, United Kingdom, ⁴The Rayne Institute, Arthritis Research UK Centre for Adolescent Rheumatology at University College London, Great Ormond Street Hospital and UCLH, University College London, London, United Kingdom, ⁵Centre for Rheumatology, University College London, London, United Kingdom, ⁶Centre for Rheumatology, Department of Medicine, University College London, London, United Kingdom, ⁷Arthritis Research UK Centre for Adolescent Rheumatology at University College London, Great Ormond Street Hospital and UCLH, University College London, London, United Kingdom, ⁸Centre for Rheumatology Research, University College Hospital London, London, United Kingdom
Background/Purpose: Raised levels of Rheumatoid Factor (RhF) and antibodies to citrullinated proteins (ACPA), detected in the clinic using combinations of cyclic citrullinated peptides (CCP), are…
Abstract Number: 3150 • 2015 ACR/ARHP Annual Meeting
Virtual Peer-to-Peer Mentoring Support for Adolescents with Juvenile Idiopathic Arthritis: The Virtual Peer-to-Peer Program
Jennifer N. Stinson¹, Sara Ahola Kohut^2,3, Khush Amaria², Mary J. Bell⁴, Paula Forgeron⁵, Miriam Kaufman⁶, Nadia Luca⁷ and Lynn R. Spiegel⁸, ¹Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, ON, Canada, ²Hospital for Sick Children, Toronto, ON, Canada, ³University of Toronto, Toronto, ON, Canada, ⁴Rheum Div/Univ of Toronto, University of Toronto, Toronto, ON, Canada, ⁵University of Ottawa, Ottawa, ON, Canada, ⁶Adolescent Medicine, The Hospital for Sick Children, Toronto, ON, Canada, ⁷Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ⁸Rheumatology/Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada
Background/Purpose: Juvenile Idiopathic Arthritis (JIA) is a common chronic disease that results in physical and emotional symptoms as well as difficulties in social and role…
Abstract Number: 1468 • 2015 ACR/ARHP Annual Meeting
The Proposed Outcome Parameters of the Multinational Interdisciplinary Working Group for Uveitis in Childhood (MIWGUC) with Uveitis Disability VAS Score Correspond Significantly with Uveitis “Classicaly Assessed” Uveitis Activity
Ivan Foeldvari¹, Sandra Schenck², Gabriele Simonini³, Cinzia DeLibero⁴, Gabriele Brumm⁵, Kaisu Kotaniemi⁶, Susan Mary Nielsen⁷, Regitze Bangsgaard⁷, Irene Pontikaki⁸, Valeria Maria Gerloni⁸, Elisabetta Miserocchi⁹, Vasco Miranda¹⁰, Margarida Guedes¹¹, Sheila T. Angeles-Han¹², Steven Yeh¹³, Jordi Anton¹⁴, Rosa Bou Torrent¹⁵, Carmen García de Vicuña¹⁶, Martina Niewerth¹⁷ and Arnd Heiligenhaus¹⁸, ¹Hamburger Zentrum für Kinder-und Jugendrheumatologie, Hamburg, Germany, ²Deutsches Rheuma-Forschungszentrum, Berlin, Germany, ³Pediatric Rheumatology, Pediatric Rheumatology Unit, Anna Meyer Children's Hospital-University of Florence, Firenze, Italy, ⁴Ophthalmology Unit, Anna Meyer Children's Hospital, Florence, Italy, ⁵Klinik und Polyklinikum für Augenheilkunde, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany, ⁶Ophthalmology Department, Rheumatism Foundation Hospital, Heinola, Finland, ⁷Rigshospitalet, Copenhagen, Denmark, ⁸Dipartimento di Reumatologia, Università di Milano - Istituto Gaetano Pini, Milano, Italy, ⁹Department of Ophthalmology, Scientific Institute San Raffaele, University Vita-Salute, Milan, Italy, ¹⁰Centro Hospitalar do Porto, Porto, Portugal, ¹¹Hospital de Santo António - Centro Hospitalar do Porto, Porto, Portugal, ¹²Pediatrics, Emory Children's Center, Atlanta, GA, ¹³Ophthalmology, Emory University School of Medicine, Atlanta, GA, ¹⁴Unitat de Reumatologia Pediàtrica, Hospital Sant Joan de Déu, Barcelona, Spain, ¹⁵Pediatrics Department, Pediatric Rheumatology Unit, Universitat de Barcelona, Hospital Sant Joan de Deu, Barcelona, Spain, ¹⁶Universitat de Barcelona, Hospital Sant Joan de Deu, Barcelona, Spain, ¹⁷Epidemiology, German Rheumatism Research Centre, Berlin, Germany, ¹⁸Department of Ophthalmology at St. Franziskus Hospital Muenster, University of Duisberg-Essen, Muenster, Germany
Background/Purpose: Juvenile idiopathic arthritis (JIA) associated uveitis is one of the most severe comorbidities of JIA and occurs in around 10% of JIA patients. There…
Abstract Number: 3178 • 2015 ACR/ARHP Annual Meeting
Tocilizumab in Refractory Uveitis Associated to Juvenile Idiopathic Arthritis. Multicenter Study of 13 Cases
Montserrat Santos-Gómez¹, Vanesa Calvo-Río¹, Ricardo Blanco¹, Inmaculada Calvo², Marina Mesquida³, Alfredo Adan³, M. Victoria Hernández⁴, Olga Maiz Alonso⁵, Antonio Atanes-Sandoval⁶, Beatriz Bravo⁷, Consuelo Modesto⁸, Gisela Diaz Soriano⁹, Javier Loricera¹, Leyre Riancho-Zarrabeitia¹, Natalia Palmou¹ and Miguel Angel Gonzalez-Gay¹, ¹Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ²Rheumatology, Hospital La Fe, Valencia, Spain, ³Ophthalmology, Hospital Clinic, Barcelona, Spain, ⁴Arthritis Unit, Rheumatology, Hospital Clinic, Barcelona, Spain, ⁵Rheumatology, Donostia University Hospital, Donostia, Spain, ⁶Rheumatology, Complejo Hospitalario Universitario de La Coruña, La Coruña, Spain, ⁷Rheumatology, Hospital Universitario HUVN, Granada, Spain, ⁸Rheumatology, Hospital HSLL, Palma de Mallorca, Spain, ⁹Rheumatology, Hospital Regional Universitario de Málaga, Málaga, Spain
Background/Purpose: To assess the efficacy of Tocilizumab (TCZ) in refractory uveitis associated to juvenile idiopathic arthritis (JiA).Methods: Multicenter study of uveitis related to JiA…
Abstract Number: 1470 • 2015 ACR/ARHP Annual Meeting
A Population-Based Study of Outcomes of Patients with Juvenile Idiopathic Arthritis (JIA) Compared to Non-JIA Subjects
Megan L. Krause¹, J.A. Zamora-Legoff², Cynthia S. Crowson³, Thomas Mason II¹, Theresa Wampler Muskardin² and Eric L. Matteson⁴, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Division of Rheumatology, Mayo Clinic, Rochester, MN, ³Health Sciences Research, Mayo Clinic, Rochester, MN, ⁴Division of Rheumatology, Department of Internal Medicine and Department of Health Sciences Research, Mayo Clinic, Rochester, MN
Background/Purpose: The impact of juvenile idiopathic arthritis (JIA) is not confined to joint involvement in children but rather widespread effects extending to adulthood. This study…
Abstract Number: 3245 • 2015 ACR/ARHP Annual Meeting
Factors Associated with Physical Activity in Older Children with Juvenile Idiopathic Arthritis
Jennifer R. Horonjeff¹, Shira Weiner², Susan Klepper³, Ali Sheikhzadeh², Philip Kahn⁴ and Sherri Weiser², ¹Ergonomics and Biomechanics, New York University, New York, NY, ²Orthopedics, New York University, New York, NY, ³Physical Therapy Program, Columbia University, New York, NY, ⁴Pediatric Rheumatology, New York University, New York, NY
Background/Purpose: The purpose of this study was to examine factors associated with physical activity (PA) in children with JIA. PA is important for the physical,…
Abstract Number: 1475 • 2015 ACR/ARHP Annual Meeting
Fatigue, Quality of SLEEP and PAIN in Children with Juvenile Idiopathic Arthritis
Ela Tarakci¹, Saime Nilay Baydogan², Kenan Barut³ and Ozgur Kasapcopur⁴, ¹Division of Physiotherapy and Rehabilitation, Faculty of Health Science, Istanbul University,, Associate Professor, Istanbul, Turkey, ²Division of Physiotherapy and Rehabilitation, Faculty of Health Science, Istanbul University,, Assistant Professor, Istanbul, Turkey, ³Pediatric Rheumatology, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey, ⁴Istanbul University, Cerrahpasa Medical School, Department of Pediatric Rheumatology, Professor of Pediatric Rheumatology, Istanbul, Turkey
Background/Purpose: Juvenile Idiopathic Arthritis (JIA) is one of the most common rheumatic diseases in childhood, affecting at least 1 in 1000 children (1). Children with…
Abstract Number: 1479 • 2015 ACR/ARHP Annual Meeting
Qualitative Assessment of Patient Important Long-Term Outcomes in Juvenile Idiopathic Arthritis
Melissa L. Mannion¹, Michelle Williams², Nataliya Ivankova³, Gerald McGwin Jr.⁴, Kenneth G. Saag⁵ and Timothy Beukelman⁶, ¹Pediatrics, University of Alabama at Birmingham, Birmingham, AL, ²School of Public Health, University of Alabama at Birmingham, Birmingham, AL, ³Health Services Administration, University of Alabama at Birmingham, Birmingham, AL, ⁴Epidemiology, University of Alabama at Birmingham, Birmingham, AL, ⁵University of Alabama at Birmingham, Birmingham, AL, ⁶Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: The aim of this study was to identify and characterize the factors that JIA patients in young adulthood use to define a successful disease…
Abstract Number: 1482 • 2015 ACR/ARHP Annual Meeting
Temporomandibular Pain in Patients with Juvenile Idiopathic Arthritis
Peter Stoustrup¹, Marinka Twilt², Bernd Koos³, N Tzaribachev⁴, Troels Herlin⁵, Thomas Klit Pedersen⁶ and Lynn R. Spiegel⁷, ¹Section of Orthodontics, University of Aarhus, Aarhus C, Denmark, ²Pediatric Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ³Orthodontics, University of Rostock, Rostock, Germany, ⁴Pediatric Rheumatology, PRI - Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany, ⁵Pediatric Rheumatology Clinic, Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark, ⁶orthodontics, Aarhus University Hospital/Dental school, Aarhus, Denmark, ⁷Rheumatology/Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada
Background/Purpose: Joint pain is a primary symptom in Juvenile Idiopathic Arthritis (JIA). Experience of pain has been shown to be a significant predictor of impaired…
Abstract Number: 2026 • 2015 ACR/ARHP Annual Meeting
A Novel Technique for Quantifying Synovial Enhancement of Temporomandibular Joints from Mris of Patients with Juvenile Idiopathic Arthritis
Cory M. Resnick¹, Pouya Vakilian², Micheal Breen³, David Zurakowski⁴, Zachary S. Peacock⁵ and Leonard B. Kaban⁵, ¹Plastics and Oral Surgery, Boston Children's Hospital, boston, MA, ²Harvard School of Dental Medicine, Boston, MA, ³Radiology, Boston Children's Hospital, Boston, MA, ⁴Departments of Anesthesia and Surgery, Boston Children’s Hospital, Boston, MA, ⁵Oral and Maxillofacial Surgery, Massachusetts General Hospital, Boston, MA
Background/Purpose: Juvenile Idiopathic Arthritis (JIA) commonly affects the temporomandibular joints (TMJ) and may cause growth disturbance, functional limitation and facial deformity. Early diagnosis and management…
Abstract Number: 2171 • 2015 ACR/ARHP Annual Meeting
A Comparison of Maternal Outcomes in Women with and without Juvenile Idiopathic Arthritis
Debbie Ehrmann Feldman¹, Sasha Bernatsky², Evelyne Vinet³, Ciarán M. Duffy⁴, Elizabeth Hazel⁵, Garbis Meshefedjian⁶, Marie-Pierre Sylvestre⁷ and Anick Bérard¹, ¹Université de Montréal, Montréal, QC, Canada, ²Rheum/Clin. Epid., McGill MUHC/RVH, Montreal, QC, Canada, ³McGill University Health Centre, Montreal, QC, Canada, ⁴Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ⁵Rhematology, McGill University Health Centre, Montreal, QC, Canada, ⁶Public Health Department of Montreal, Montreal, QC, Canada, ⁷Université de Montréal, Montreal, QC, Canada
Background/Purpose: Although there is a higher frequency of adverse maternal outcomes in mother with rheumatoid arthritis, little is known regarding mothers with juvenile idiopathic arthritis…
Abstract Number: 2416 • 2015 ACR/ARHP Annual Meeting
Pharmacokinetics, Safety, and Tolerability of Tofacitinib in Pediatric Patients from Six to Less Than Eighteen Years of Age with Juvenile Idiopathic Arthritis
Hermine I. Brunner¹, Nicolino Ruperto², Nikolay Tzaribachev³, Zbigniew Zuber⁴, Elena Koskova⁵, Ivan Foeldvari⁶, Eizbieta Smolewska⁷, Gerd Horneff⁸, Charles Mebus⁹, Umberto Conte¹⁰, Rong Wang⁹, Christine Alvey⁹, Manisha Lamba⁹, Anasuya Hazra¹¹, Daniel Lovell¹² and Alberto Martini¹³, ¹Pediatric Rheumatology Collaborative Study Group, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Istituto G. Gaslini, Pediatria II, PRINTO, Genoa, Italy, ³Pediatric Rheumatology, Bad Bramstedt, Germany, ⁴St Louis Children’s Hospital ODS Rheumatology and Neurology, Krakow, Poland, ⁵Institute of Rheumatic Diseases, Piestany, Slovakia, ⁶Hamburger Zentrum für Kinder-und Jugendrheumatologie, Hamburg, Germany, ⁷Department of Pediatric Cardiology and Rheumatology, Medical University of Lodz, Lodz, Poland, ⁸Asklepios Klinik Sankt Augustin GmbH, Sankt Augustin, Germany, ⁹Pfizer Inc, Groton, CT, ¹⁰Pfizer Inc, New York, NY, ¹¹Pfizer Inc, Collegeville, PA, ¹²Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ¹³Istituto G. Gaslini, Pediatria II, PRINTO, and University of Genoa, Genoa, Italy
Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of adult patients with rheumatoid arthritis (RA). We report the pharmacokinetics (PK), safety and…
Abstract Number: 2423 • 2015 ACR/ARHP Annual Meeting
An Open-Label Extension Study to Assess the Long-Term Safety and Clinical Benefit of Etanercept on Children and Adolescents with Extended Oligoarticular Juvenile Idiopathic Arthritis, Enthesitis-Related Arthritis, or Psoriatic Arthritis: A 4-Year Update
Nicolino Ruperto¹, Tamas Constantin², Ivan Foeldvari³, Jelena Vojinovic⁴, Gerd Horneff⁵, Rubén Burgos-Vargas⁶, Irina Nikishina⁷, Jonathan Akikusa⁸, Tadej Avcin⁹, Jeffrey Chaitow¹⁰, Elena Koskova¹¹, Bernard R. Lauwerys¹², Inmaculada Calvo-Penedes¹³, Berit Flato¹⁴, Maria Luz Gamir Gamir¹⁵, Hans-Iko Huppertz¹⁶, Juan Jose Jaller Raad¹⁷, Katerina Jarosova¹⁸, Jordi Anton¹⁹, Marie Macku²⁰, William Jose Otero Escalante²¹, Lidia Rutkowska-Sak²², Ralf Trauzeddel²³, Carine Wouters²⁴, Ronald Pedersen²⁵, Sameer Kotak²⁶, Jack F Bukowski²⁷, Tina Hinnershitz²⁸, Bonnie Vlahos²⁹ and Alberto Martini³⁰, ¹Pediatria II, PRINTO, Istituto G. Gaslini, Universita' di Genova, Genova, Italy, ²Semmelweis University, Budapest, Hungary, ³Hamburg Centre for Child and Adolescent Rheumatology, Hamburg, Germany, ⁴Faculty of Medicine, University of Nis, Nis, Serbia, ⁵Asklepios Clinic Sankt Augustin, Sankt Augustin, Germany, ⁶Rheumatology, Hospital General de Mexico, Mexico city, Mexico, ⁷V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia, ⁸Rheumatology, Royal Children's Hospital, Melbourne, Australia, ⁹Allergology, Rheumatology and Clinical Immunology, University Medical Center Ljubljana, Ljubljana, Slovenia, ¹⁰The Sydney Children's Hospital Network, Sydney, Australia, ¹¹National Institute of Rheumatic Diseases, Piestany, Slovakia, ¹²Cliniques Universitaires Saint-Luc, Brussels, Belgium, ¹³Hospital Universitario y Piltecnico La Fe, Valencia, Spain, ¹⁴Oslo University Hospital, Oslo, Norway, ¹⁵Rheumatology, Hospital Ramon y Cajal Unidad de Reumatologia Pediatrica, Madrid, Spain, ¹⁶Klinikum Bremen-Mitte, Prof.-Hess-Kinderklinik, Bremen, Germany, ¹⁷Centro de Reumatologia y Ortopedia, Barranquilla, Colombia, ¹⁸Revmatologicky ustav, Prague, Czech Republic, ¹⁹Unitat de Reumatologia Pediàtrica, Hospital Sant Joan de Déu, Barcelona, Spain, ²⁰1, Facutly Children's Hospital Brno, Brno, Czech Republic, ²¹Servimed S.A.S, Santander, Colombia, ²²Instytut Reumatologii, Klinika i Poliklinika Reumatologii Wieku Rozwojowego, Warszawa, Poland, ²³HELIOS Klinikum Berlin-Buch Klinik fuer Kinder- und Jugendmedizin, Berlin, Germany, ²⁴UZ Leuven, Leuven, Belgium, ²⁵Department of Biostatistics, Pfizer, Collegeville, PA, ²⁶Global Health and Value, Pfizer, New York, NY, ²⁷Pfizer, Collegeville, PA, ²⁸Specialty Care MDG, Pfizer, Collegeville, PA, ²⁹GIPB - Clinical Sciences, Pfizer, Collegeville, PA, ³⁰Istituto G. Gaslini, Universita' di Genova, Genova, Italy
Background/Purpose: A Phase 3b, open-label, multicenter study (CLIPPER; NCT00962741) demonstrated the efficacy of etanercept (ETN) in subjects with the extended oligoarticular (eo), enthesitis-related (ERA), and…
Abstract Number: 1444 • 2014 ACR/ARHP Annual Meeting
The Vocational Experiences of Young People with Juvenile Idiopathic Arthritis and the Role of the Multidisciplinary Team Supporting Positive Employment Outcomes
Helen Hanson¹, Ruth Hart², Alison Jordan³, Rachel Tattersall⁴, Ben Thompson¹ and Helen E. Foster⁵, ¹Rheumatology, Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom, ²Institute of Health and Society, Newcastle University, Newcastle upon Tyne, United Kingdom, ³Rheumatology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom, ⁴Rheumatology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom, ⁵Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
Background/Purpose: Recent decades have seen marked changes in the management of juvenile idiopathic arthritis (JIA), with improved clinical outcomes for many patients. However, unemployment rates…

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