Abstracts tagged "juvenile idiopathic arthritis (JIA)"

Abstract Number: 3245 • 2015 ACR/ARHP Annual Meeting
Factors Associated with Physical Activity in Older Children with Juvenile Idiopathic Arthritis
Jennifer R. Horonjeff¹, Shira Weiner², Susan Klepper³, Ali Sheikhzadeh², Philip Kahn⁴ and Sherri Weiser², ¹Ergonomics and Biomechanics, New York University, New York, NY, ²Orthopedics, New York University, New York, NY, ³Physical Therapy Program, Columbia University, New York, NY, ⁴Pediatric Rheumatology, New York University, New York, NY
Background/Purpose: The purpose of this study was to examine factors associated with physical activity (PA) in children with JIA. PA is important for the physical,…
Abstract Number: 1475 • 2015 ACR/ARHP Annual Meeting
Fatigue, Quality of SLEEP and PAIN in Children with Juvenile Idiopathic Arthritis
Ela Tarakci¹, Saime Nilay Baydogan², Kenan Barut³ and Ozgur Kasapcopur⁴, ¹Division of Physiotherapy and Rehabilitation, Faculty of Health Science, Istanbul University,, Associate Professor, Istanbul, Turkey, ²Division of Physiotherapy and Rehabilitation, Faculty of Health Science, Istanbul University,, Assistant Professor, Istanbul, Turkey, ³Pediatric Rheumatology, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey, ⁴Istanbul University, Cerrahpasa Medical School, Department of Pediatric Rheumatology, Professor of Pediatric Rheumatology, Istanbul, Turkey
Background/Purpose: Juvenile Idiopathic Arthritis (JIA) is one of the most common rheumatic diseases in childhood, affecting at least 1 in 1000 children (1). Children with…
Abstract Number: 1479 • 2015 ACR/ARHP Annual Meeting
Qualitative Assessment of Patient Important Long-Term Outcomes in Juvenile Idiopathic Arthritis
Melissa L. Mannion¹, Michelle Williams², Nataliya Ivankova³, Gerald McGwin Jr.⁴, Kenneth G. Saag⁵ and Timothy Beukelman⁶, ¹Pediatrics, University of Alabama at Birmingham, Birmingham, AL, ²School of Public Health, University of Alabama at Birmingham, Birmingham, AL, ³Health Services Administration, University of Alabama at Birmingham, Birmingham, AL, ⁴Epidemiology, University of Alabama at Birmingham, Birmingham, AL, ⁵University of Alabama at Birmingham, Birmingham, AL, ⁶Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: The aim of this study was to identify and characterize the factors that JIA patients in young adulthood use to define a successful disease…
Abstract Number: 1482 • 2015 ACR/ARHP Annual Meeting
Temporomandibular Pain in Patients with Juvenile Idiopathic Arthritis
Peter Stoustrup¹, Marinka Twilt², Bernd Koos³, N Tzaribachev⁴, Troels Herlin⁵, Thomas Klit Pedersen⁶ and Lynn R. Spiegel⁷, ¹Section of Orthodontics, University of Aarhus, Aarhus C, Denmark, ²Pediatric Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ³Orthodontics, University of Rostock, Rostock, Germany, ⁴Pediatric Rheumatology, PRI - Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany, ⁵Pediatric Rheumatology Clinic, Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark, ⁶orthodontics, Aarhus University Hospital/Dental school, Aarhus, Denmark, ⁷Rheumatology/Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada
Background/Purpose: Joint pain is a primary symptom in Juvenile Idiopathic Arthritis (JIA). Experience of pain has been shown to be a significant predictor of impaired…
Abstract Number: 2026 • 2015 ACR/ARHP Annual Meeting
A Novel Technique for Quantifying Synovial Enhancement of Temporomandibular Joints from Mris of Patients with Juvenile Idiopathic Arthritis
Cory M. Resnick¹, Pouya Vakilian², Micheal Breen³, David Zurakowski⁴, Zachary S. Peacock⁵ and Leonard B. Kaban⁵, ¹Plastics and Oral Surgery, Boston Children's Hospital, boston, MA, ²Harvard School of Dental Medicine, Boston, MA, ³Radiology, Boston Children's Hospital, Boston, MA, ⁴Departments of Anesthesia and Surgery, Boston Children’s Hospital, Boston, MA, ⁵Oral and Maxillofacial Surgery, Massachusetts General Hospital, Boston, MA
Background/Purpose: Juvenile Idiopathic Arthritis (JIA) commonly affects the temporomandibular joints (TMJ) and may cause growth disturbance, functional limitation and facial deformity. Early diagnosis and management…
Abstract Number: 2171 • 2015 ACR/ARHP Annual Meeting
A Comparison of Maternal Outcomes in Women with and without Juvenile Idiopathic Arthritis
Debbie Ehrmann Feldman¹, Sasha Bernatsky², Evelyne Vinet³, Ciarán M. Duffy⁴, Elizabeth Hazel⁵, Garbis Meshefedjian⁶, Marie-Pierre Sylvestre⁷ and Anick Bérard¹, ¹Université de Montréal, Montréal, QC, Canada, ²Rheum/Clin. Epid., McGill MUHC/RVH, Montreal, QC, Canada, ³McGill University Health Centre, Montreal, QC, Canada, ⁴Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ⁵Rhematology, McGill University Health Centre, Montreal, QC, Canada, ⁶Public Health Department of Montreal, Montreal, QC, Canada, ⁷Université de Montréal, Montreal, QC, Canada
Background/Purpose: Although there is a higher frequency of adverse maternal outcomes in mother with rheumatoid arthritis, little is known regarding mothers with juvenile idiopathic arthritis…
Abstract Number: 2416 • 2015 ACR/ARHP Annual Meeting
Pharmacokinetics, Safety, and Tolerability of Tofacitinib in Pediatric Patients from Six to Less Than Eighteen Years of Age with Juvenile Idiopathic Arthritis
Hermine I. Brunner¹, Nicolino Ruperto², Nikolay Tzaribachev³, Zbigniew Zuber⁴, Elena Koskova⁵, Ivan Foeldvari⁶, Eizbieta Smolewska⁷, Gerd Horneff⁸, Charles Mebus⁹, Umberto Conte¹⁰, Rong Wang⁹, Christine Alvey⁹, Manisha Lamba⁹, Anasuya Hazra¹¹, Daniel Lovell¹² and Alberto Martini¹³, ¹Pediatric Rheumatology Collaborative Study Group, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Istituto G. Gaslini, Pediatria II, PRINTO, Genoa, Italy, ³Pediatric Rheumatology, Bad Bramstedt, Germany, ⁴St Louis Children’s Hospital ODS Rheumatology and Neurology, Krakow, Poland, ⁵Institute of Rheumatic Diseases, Piestany, Slovakia, ⁶Hamburger Zentrum für Kinder-und Jugendrheumatologie, Hamburg, Germany, ⁷Department of Pediatric Cardiology and Rheumatology, Medical University of Lodz, Lodz, Poland, ⁸Asklepios Klinik Sankt Augustin GmbH, Sankt Augustin, Germany, ⁹Pfizer Inc, Groton, CT, ¹⁰Pfizer Inc, New York, NY, ¹¹Pfizer Inc, Collegeville, PA, ¹²Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ¹³Istituto G. Gaslini, Pediatria II, PRINTO, and University of Genoa, Genoa, Italy
Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of adult patients with rheumatoid arthritis (RA). We report the pharmacokinetics (PK), safety and…
Abstract Number: 2423 • 2015 ACR/ARHP Annual Meeting
An Open-Label Extension Study to Assess the Long-Term Safety and Clinical Benefit of Etanercept on Children and Adolescents with Extended Oligoarticular Juvenile Idiopathic Arthritis, Enthesitis-Related Arthritis, or Psoriatic Arthritis: A 4-Year Update
Nicolino Ruperto¹, Tamas Constantin², Ivan Foeldvari³, Jelena Vojinovic⁴, Gerd Horneff⁵, Rubén Burgos-Vargas⁶, Irina Nikishina⁷, Jonathan Akikusa⁸, Tadej Avcin⁹, Jeffrey Chaitow¹⁰, Elena Koskova¹¹, Bernard R. Lauwerys¹², Inmaculada Calvo-Penedes¹³, Berit Flato¹⁴, Maria Luz Gamir Gamir¹⁵, Hans-Iko Huppertz¹⁶, Juan Jose Jaller Raad¹⁷, Katerina Jarosova¹⁸, Jordi Anton¹⁹, Marie Macku²⁰, William Jose Otero Escalante²¹, Lidia Rutkowska-Sak²², Ralf Trauzeddel²³, Carine Wouters²⁴, Ronald Pedersen²⁵, Sameer Kotak²⁶, Jack F Bukowski²⁷, Tina Hinnershitz²⁸, Bonnie Vlahos²⁹ and Alberto Martini³⁰, ¹Pediatria II, PRINTO, Istituto G. Gaslini, Universita' di Genova, Genova, Italy, ²Semmelweis University, Budapest, Hungary, ³Hamburg Centre for Child and Adolescent Rheumatology, Hamburg, Germany, ⁴Faculty of Medicine, University of Nis, Nis, Serbia, ⁵Asklepios Clinic Sankt Augustin, Sankt Augustin, Germany, ⁶Rheumatology, Hospital General de Mexico, Mexico city, Mexico, ⁷V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia, ⁸Rheumatology, Royal Children's Hospital, Melbourne, Australia, ⁹Allergology, Rheumatology and Clinical Immunology, University Medical Center Ljubljana, Ljubljana, Slovenia, ¹⁰The Sydney Children's Hospital Network, Sydney, Australia, ¹¹National Institute of Rheumatic Diseases, Piestany, Slovakia, ¹²Cliniques Universitaires Saint-Luc, Brussels, Belgium, ¹³Hospital Universitario y Piltecnico La Fe, Valencia, Spain, ¹⁴Oslo University Hospital, Oslo, Norway, ¹⁵Rheumatology, Hospital Ramon y Cajal Unidad de Reumatologia Pediatrica, Madrid, Spain, ¹⁶Klinikum Bremen-Mitte, Prof.-Hess-Kinderklinik, Bremen, Germany, ¹⁷Centro de Reumatologia y Ortopedia, Barranquilla, Colombia, ¹⁸Revmatologicky ustav, Prague, Czech Republic, ¹⁹Unitat de Reumatologia Pediàtrica, Hospital Sant Joan de Déu, Barcelona, Spain, ²⁰1, Facutly Children's Hospital Brno, Brno, Czech Republic, ²¹Servimed S.A.S, Santander, Colombia, ²²Instytut Reumatologii, Klinika i Poliklinika Reumatologii Wieku Rozwojowego, Warszawa, Poland, ²³HELIOS Klinikum Berlin-Buch Klinik fuer Kinder- und Jugendmedizin, Berlin, Germany, ²⁴UZ Leuven, Leuven, Belgium, ²⁵Department of Biostatistics, Pfizer, Collegeville, PA, ²⁶Global Health and Value, Pfizer, New York, NY, ²⁷Pfizer, Collegeville, PA, ²⁸Specialty Care MDG, Pfizer, Collegeville, PA, ²⁹GIPB - Clinical Sciences, Pfizer, Collegeville, PA, ³⁰Istituto G. Gaslini, Universita' di Genova, Genova, Italy
Background/Purpose: A Phase 3b, open-label, multicenter study (CLIPPER; NCT00962741) demonstrated the efficacy of etanercept (ETN) in subjects with the extended oligoarticular (eo), enthesitis-related (ERA), and…
Abstract Number: 2432 • 2015 ACR/ARHP Annual Meeting
The Preventive Effect of Methotrexate on Uveitis Onset in JIA Depends on Uveitis Risk Factors
Mikhail Kostik¹, Ekaterina Gaidar¹, Margarita Dubko¹, Ludmila Snegireva², Vera Masalova², Irina Chikova¹, Eugenia Isupova³, Tatiana Nikitina⁴, Elena Serogodskaya¹, Olga Kalashnikova¹, Angelo Ravelli⁵ and Vyacheslav Chasnyk³, ¹State Pediatric Medical University, Saint-Petersburg, Russia, ²Hospital Pediatrics, State Pediatric Medical University, Saint-Petersburg, Russia, ³Hospital Pediatry, State Pediatric Medical University, Saint-Petersburg, Russia, ⁴State Pediatric Medical University, St. Petersburg, Russia, ⁵Pediatria-II, IRCCS G. Gaslini and University of Genova, Genova, Italy
Background/Purpose: Uveitis is the most common extra-articular manifestation of juvenile idiopathic arthritis (JIA), often entirely asymptomatic but could be sight-threatening. The main predictors of uveitis…
Abstract Number: 2437 • 2015 ACR/ARHP Annual Meeting
Experience with Tocilizumab for Treatment of 56 Children with Systemic Juvenile Idiopathic Arthritis in the German JIA Biologics Register
Gerd Horneff¹, Gerd Ganser², Johannes Peter Haas³, Toni Hospach⁴, Ralf Trauzeddel⁵, Hans-Iko Huppertz⁶, J B. Kuemmerle-Deschner⁷, Kirsten Minden⁸ and BIKER Registry Study Group, ¹Asklepios Clinic Sankt Augustin, Sankt Augustin, Germany, ²Pediatric Rheumatology, Sankt Josef Stift, Sendenhorst, Germany, ³German Centre for Rheumatology in Children and Young People, Garmisch-Partenkirchen, Germany, ⁴Pediatrics, Olgahospital, Klinikum Stuttgart, Stuttgard, Germany, ⁵HELIOS Klinikum Berlin-Buch Klinik fuer Kinder- und Jugendmedizin, Berlin, Germany, ⁶PRINTO, IRCCS G. Gaslini, Genoa, Italy, ⁷Pediatrics, University Hospital Tuebingen, Tuebingen, Germany, ⁸DRFG, Berlin, Germany
Background/Purpose: Tocilizumab (TOC) has become a valuable option for treatment of systemic juvenile idiopathic arthritis (sJIA), which significantly improved the outcome of patients. The aim…
Abstract Number: 930 • 2015 ACR/ARHP Annual Meeting
Evaluation of Temporomandibular Joint Arthritis with Ultrasound in Juvenile Idiopathic Arthritis
Edward J. Oberle^1,2, James Nocton³ and Arthur Meyers⁴, ¹Pediatrics, Ohio State University, Columbus, OH, ²Pediatric Rheumatology, Nationwide Children's Hospital, Columbus, OH, ³Pediatrics, Medical College of Wisconsin, Milwaukee, WI, ⁴Radiology, Children's Hospital of Wisconsin, Milwaukee, WI
Background/Purpose: Temporomandibular joint (TMJ) arthritis is a common yet widely under recognized feature of Juvenile Idiopathic Arthritis (JIA). It is often clinically silent and difficult…
Abstract Number: 2444 • 2015 ACR/ARHP Annual Meeting
Accelerometer-Assessed Daily Physical Activity in Relation to Pain Cognitions and Quality of Life in Juvenile Idiopathic Arthritis
Mette Noergaard¹, Johanne Lomholt², Mikael Thastum², Morten Herlin³, Marinka Twilt⁴ and Troels Herlin⁴, ¹Department of Physiotherapy, Aarhus University Hospital, Aarhus, Denmark, ²Psychology and Social Sciences, Aarhus University, Aarhus, Denmark, ³Pediatrics, Aarhus University Hospital, Aarhus, Denmark, ⁴Pediatric Rheumatology Clinic, Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark
Background/Purpose: Juvenile Idiopathic Arthritis (JIA) has been associated with decreased physical activity (PA). However, accurate, objective measurements of PA related to potential factors limiting PA…
Abstract Number: 957 • 2015 ACR/ARHP Annual Meeting
Double Blind Placebo Controlled Randomized Trial of Probiotics in Enthesitis-Related-Arthritis Category of JIA: Effect on Clinical and Immunological Parameters
Anuj Shukla¹, Priyanka Gaur² and Amita Aggarwal¹, ¹Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, ²Department of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
Background/Purpose: Gut microflora influences the development and homeostasis of the immune system. Dysbiosis has been reported in various immuno-inflammatory diseases. Pathogenesis of enthesitis-related-arthritis (ERA) category…
Abstract Number: 2445 • 2015 ACR/ARHP Annual Meeting
Development and Usability Testing of an Ipad-Based Psycho-Educational Game for Children with Juvenile Idiopathic Arthritis and Their Parents
Jennifer N. Stinson¹, Adam M. Huber², Mark Connelly³, Nadia Luca⁴, Lynn R. Spiegel⁵, Argerie Tsimicalis⁶, Stephanie Luca⁷, Roberta Berard⁸, Julie Barsalou⁹, Sarah Campillo¹⁰, Paul Dancey¹¹, Ciarán M. Duffy¹², Brian Feldman¹³, Nicole Johnson⁴, Patrick McGrath¹⁴, Natalie J. Shiff¹⁵, Shirley M Tse¹⁶, Lori B. Tucker¹⁷ and J. Charles Victor¹⁸, ¹Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, ON, Canada, ²Pediatric rheumatology, IWK Health Centre, Halifax, NS, Canada, ³Psychology, University of Kansas Medical Center, Kansas City, KS, ⁴Pediatrics/Alberta Children's Hospital, Department of Pediatrics/University of Calgary, Calgary, AB, Canada, ⁵Rheumatology/Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada, ⁶McGill University, Montreal, QC, Canada, ⁷The Hospital for Sick Children, Toronto, ON, Canada, ⁸Children's Hospital of Western Ontario, London, ON, Canada, ⁹CHU Sainte-Justine, Université de Montréal, Montreal, QC, Canada, ¹⁰Rheumatology, Montreal Children's Hospital, Montreal, QC, Canada, ¹¹Health Science Centre, Memorial University of Newfoundland, St Johns, NF, Canada, ¹²Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ¹³Division of Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, ¹⁴IWK Health Centre, Halifax, NS, Canada, ¹⁵Pediatric Rheumatology, University of Saskatchewan, Saskatoon, SK, Canada, ¹⁶Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹⁷Rheumatology, BC Children's Hospital, Vancouver, BC, Canada, ¹⁸University of Toronto, Toronto, ON, Canada
Background/Purpose: Juvenile Idiopathic Arthritis (JIA) is a common chronic childhood illness that can negatively impact health-related quality of life (HRQL). In younger years, children manage…
Abstract Number: 302 • 2014 ACR/ARHP Annual Meeting
Qualitative Assessment of Important Long-Term Outcomes in Juvenile Idiopathic Arthritis
Melissa L. Mannion¹, Michelle Williams², Gerald McGwin Jr.³, Kenneth G. Saag⁴ and Timothy Beukelman¹, ¹Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ²School of Public Health, University of Alabama at Birmingham, Birmingham, AL, ³Epidemiology, University of Alabama at Birmingham, Birmingham, AL, ⁴Immunology & Rheumatology, The University of Alabama at Birmingham, Birmingham, AL
Background/Purpose JIA is not a childhood disease, but a chronic disease that begins in childhood. Long term outcomes that physicians and patients care most about…

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