Abstracts tagged "Juvenile dermatomyositis and natural killer (NK) cells"

Abstract Number: 1948 • 2012 ACR/ARHP Annual Meeting
Decreased C4A Gene Copy Numbers in Children with Juvenile Dermatomyositis: Association with Decreased C4 Protein and Lower Absolute Number of CD3 Negative CD16/56+ Natural Killer Cells
Lauren M. Pachman¹, Katherine E. Lintner², Yee Ling Wu², Lori J. Ferguson³, Gabrielle A. Morgan⁴, Chiang-Ching Huang⁵ and C. Yung Yu⁶, ¹Division of Pediatric Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ²The Research Institute at Nationwide Children's Hospital and The Ohio State University, Columbus, OH, ³Children's Hospital of Chicago Research Center, Cure JM Myositis Center, Chicago, IL, ⁴Cure JM Myositis Center, Ann & Robert H. Lurie Children's Hospital of Chicago Research Center, Chicago, IL, ⁵Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Center for Molecular and Human Genetics, The Research Institute at Nationwide Children's Hospital and The Ohio State University, Columbus, OH
Background/Purpose: Juvenile Dermatomyositis (JDM), a systemic vasculopathy, is member of the family of autoimmune diseases. In 56% of untreated JDM, a decrease in the absolute…

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