Abstracts tagged "joint destruction and osteoclastogenesis"

Abstract Number: 390 • 2017 ACR/ARHP Annual Meeting
S-110483, a Novel and Selective EP4 Receptor Antagonist with Anti-Bone Destruction Activities
Toshitaka Ochiai¹, Takashi Maeda², Toshie Nagayasu-Tanaka², Jun Anzai¹, Daiki Kato¹, Yuta Morisaki², Kiyoharu Ukai² and Masahiro Suda², ¹Kaken Pharmaceutical Co., LTD, Kyoto, Japan, ²Pharmacology Department, Kaken Pharmaceutical Co., LTD, Kyoto, Japan
Background/Purpose: S-110483 is our novel potent and selective EP4 receptor (EP4) antagonist. In addition to the well-known fact that EP4 antagonists have anti-inflammatory effects, it…

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Abstracts tagged "joint destruction and osteoclastogenesis"

S-110483, a Novel and Selective EP4 Receptor Antagonist with Anti-Bone Destruction Activities