Abstracts tagged "Joint destruction and matrix metalloproteinase (MMP)"

Abstract Number: 464 • 2017 ACR/ARHP Annual Meeting
Value of Matrix Metalloproteinase-3 Regarding Prediction for Joint Destruction at 1 Year Is Different between Sexes in Patients with Rheumatoid Arthritis
Yutaro Yamada¹, Kentaro Inui², Tadashi Okano³, Yuko Sugioka¹, Kenji Mamoto⁴, Kazuki Orita⁵, Tatsuya Koike⁶, Masahiro Tada⁷ and Hiroaki Nakamura³, ¹Orthopedic surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, ²Orhopedic surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, ³Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, ⁴Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, ⁵Orthopedics, Shirahama hamayu Hospital, Shirahama, Japan, ⁶Center for Senile Degenerative Disorders, Osaka City University Medical School, Osaka, Japan, ⁷Orthopedic Surgery, Osaka City General Hospital, Osaka, Japan
Background/Purpose: Serum level of MMP-3 rises by synovial inflammation in patients with rheumatoid arthritis (RA). It destroys articular cartilage such as proteoglycans so that it…

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