ACR Meeting Abstracts

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Abstracts tagged "Japanese"

  • Abstract Number: 226 • 2014 ACR/ARHP Annual Meeting

    Improved Prediction of Hip Fracture Using the Health Assessment Questionnaire-Disability Index and FRAX® in Japanese Patients with Rheumatoid Arthritis: A Prospective Observational Study

    Takefumi Furuya1, Eisuke Inoue2, Kensuke Ochi1, Osamu Ishida3, Atsuo Taniguchi4, Shigeki Momohara4 and Hisashi Yamanaka1, 1Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 2Rheumatology, Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan, 3Orthopedics, Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 4Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan

    Background/Purpose: The World Health Organization Fracture Risk Assessment Tool (FRAX®) algorithm can be used to estimate 10-year probabilities of hip and major osteoporotic fractures. Previously,…
  • Abstract Number: 223 • 2014 ACR/ARHP Annual Meeting

    Risk Factors for Clinical Vertebral Fractures in Japanese Men and Women with Rheumatoid Arthritis: Results from a Large Prospective Observational Cohort Study

    Osamu Ishida1, Takefumi Furuya2, Eisuke Inoue3, Kensuke Ochi2, Katsunori Ikari2, Atsuo Taniguchi4, Hisashi Yamanaka2 and Shigeki Momohara4, 1Orthopedics, Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 2Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 3Rheumatology, Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan, 4Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan

    Background/Purpose: Patients with rheumatoid arthritis (RA) are at high risk of developing vertebral fractures. Previously, utilizing data from our Institute of Rheumatology Rheumatoid Arthritis (IORRA)…
  • Abstract Number: 2470 • 2014 ACR/ARHP Annual Meeting

    Treatment Strategy for Maximizating the Effect of Adalimumab in Japanese Patients with Rheumatoid Arthritis : Retrospective Analyses of Data Collected from the Patient Treated with Adalimumab in Routine Clinical Practice in Hamamatsu Area

    Toshiaki Miyamoto, Rheumatology, SEIREI HAMAMATSU GENERAL HOSPITAL, Hamamatsu, Japan

    Background/Purpose: Adalimumab (ADA) showed highly efficacious in rheumatoid arthritis (RA) in the clinical trials, although there is little evidence in daily clinical practice.The clinical usefulness…
  • Abstract Number: 2418 • 2014 ACR/ARHP Annual Meeting

    Treatment Pattern and Direct Cost of Biologics for Rheumatoid Arthritis Patients: A Real-World Analysis of Nationwide Japanese Claims Data

    Naonobu Sugiyama M.D., Ph.D1, Tatsunori Murata, M.S.2, Yosuke Morishima3, Yuri Fukuma4, Yoshiyuki Shibasaki4 and Lisa Marshall5, 1Medical Affairs, Pfizer Japan Inc. RA & Inflammation Area Medical Affairs Department, Tokyo, Japan, 2Health Economics Research Group, CRECON Research and Consulting Inc., Tokyo, Japan, 3RA & Inflammation Area Medical Affairs Department, Pfizer Japan Inc. RA & Inflammation Area Medical Affairs Department, Tokyo, Japan, 4Pfizer Japan Inc. RA & Inflammation Area Medical Affairs Department, Tokyo, Japan, 5Inflammation Immunology Disease Group, Pfizer Inc. Inflammation Immunology Disease Group, Collegeville, PA

    Background/Purpose Biologics such as etanercept (ETN), adalimumab (ADA), infliximab (IFX) and tocilizumab (TCZ) have led dramatic improvement in the treatment of rheumatoid arthritis (RA), but…
  • Abstract Number: 174 • 2013 ACR/ARHP Annual Meeting

    Genetic Association On Disease Severity In Rheumatoid Arthritis: A Validation Study In Japanese Patients

    Shinji Yoshida1, Katsunori Ikari1, Koichiro Yano1, Yoshiaki Toyama2, Atsuo Taniguchi3, Hisashi Yamanaka1 and Shigeki Momohara3, 1Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 2Department of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan, 3Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan

    Background/Purpose: The disease severity of rheumatoid arthritis (RA) is objectively measured by radiographic joint destruction, which is reflective of the cumulative burden of inflammation. Recently,…
  • Abstract Number: 2800 • 2013 ACR/ARHP Annual Meeting

    Dose-Response Effects Of Denosumab, a Novel Subcutaneous RANKL Inhibitor, On The Progression Of Bone Erosion In Japanese Patients With Rheumatoid Arthritis Treated With Methotrexate: Results Of Phase II DRIVE Study – A Twelve Month Placebo Controlled, Randomized, Double Blind Study

    Tsutomu Takeuchi1, Yoshiya Tanaka2, Naoki Ishiguro3, Hisashi Yamanaka4, Toshiyuki Yoneda5, Harry K. Genant6 and Désirée van der Heijde7, 1Keio University School of Medicine, Tokyo, Japan, 2University of Occupational and Environmental Health, Kitakyushu, Japan, 3Nagoya University Graduate School of Medicine, Nagoya, Japan, 4Institute of Rheumatology Tokyo Women's Medical University, Tokyo, Japan, 5Indiana University School of Medicine, Indianapolis, IN, 6University of California, San Francisco, CCBR-Synarc, Newark, Tiburon, CA, 7Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Denosumab is a fully human monoclonal antibody (IgG2 subclass) that binds specifically to RANKL. It inhibits osteoclast-induced bone resorption by preventing the binding of…
  • Abstract Number: 2322 • 2013 ACR/ARHP Annual Meeting

    Post–Hoc Analysis Showing Better Clinical Response With The Loading Dose Of Certolizumab Pegol In Japanese Patients With Active Rheumatoid Arthritis

    Tsutomu Takeuchi1, Kazuhiko Yamamoto2,3, Hisashi Yamanaka4, Naoki Ishiguro5, Yoshiya Tanaka6, Katsumi Eguchi7, Akira Watanabe8, Hideki Origasa9, Mariko Kobayashi10, Toshiharu Shoji10, Nobuyuki Miyasaka11 and Takao Koike12, 1Department of Rheumatology, Keio University, Tokyo, Japan, 2Department of Allergy and Rhaumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 3University of Tokyo, Tokyo, Japan, 4Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 5Orthopaedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan, 6The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, 7Sasebo City General Hospital, Sasebo, Nagasaki, Japan, 8Tohoku University, Sendai, Japan, 9Division of Biostatistics and Clinical Epidemiology, University of Toyama School of Medicine, Toyama, Toyama, Japan, 10UCB Pharma, Tokyo, Japan, 11Tokyo Medical and Dental University, Tokyo, Japan, 12Rheumatology, NTT Sapporo Medical Center, Sapporo, Japan

    Background/Purpose: Certolizumab pegol (CZP) with MTX (J-RAPID; NCT00791999) and without MTX (HIKARI; NCT00791921) has demonstrated rapid and sustained improvements in disease activity in Japanese patients…
  • Abstract Number: 2323 • 2013 ACR/ARHP Annual Meeting

    Comprehensive Disease Remission Achieved By Certolizumab Pegol Treatment, and Factors Associated With Certolizumab Pegol Comprehensive Disease Remission, In Rheumatoid Arthritis Patients With Predominantly High Disease Activity

    Yoshiya Tanaka1, Kazuhiko Yamamoto2, Tsutomu Takeuchi3, Hisashi Yamanaka4, Naoki Ishiguro5, Katsumi Eguchi6, Akira Watanabe7, Hideki Origasa8, Tadao Okamoto9, Yumiko Wada9, Toshiharu Shoji9, Nobuyuki Miyasaka10 and Takao Koike11, 1The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, 2Department of Allergy and Rheumatology, The University of Tokyo, Tokyo, Japan, 3Keio University, Tokyo, Japan, 4Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 5Department of Orthopedic Surgery, Nagoya University, Nagoya, Japan, 6Sasebo City General Hospital, Sasebo, Japan, 7Tohoku University, Sendai, Japan, 8Division of Biostatistics and Clinical Epidemiology, University of Toyama School of Medicine, Toyama, Toyama, Japan, 9UCB Pharma, Tokyo, Japan, 10Department of Medicine and Rheumatology, Graduate School of Medicine and Dentistry, Tokyo Medical and Dental University, Tokyo, Japan, 11NTT Sapporo Medical Center, Sapporo, Japan

    Background/Purpose: The therapeutic goals of treating rheumatoid arthritis (RA) are clinical, structural and functional remissions.1,2 Simultaneously achieving all three has been referred to as comprehensive…
  • Abstract Number: 1796 • 2013 ACR/ARHP Annual Meeting

    12-Week Results Of a Phase 2b Dose-Ranging Study Of Baricitinib, An Oral JAK1/ JAK2 Inhibitor In Japanese Patients With Rheumatoid Arthritis On Background Methotrexate Therapy

    Yoshiya Tanaka1, Kahaku Emoto2, Mika Tsujimoto2, Douglas E. Schlichting3 and William Macias3, 1The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, 2Eli Lilly Japan K.K., Kobe, Japan, 3Eli Lilly and Company, Indianapolis, IN

    Background/Purpose: Baricitinib (formerly LY3009104/INCB028050), a novel, oral inhibitor of JAK1 and JAK2 in the JAK-STAT signaling pathway, has been evaluated in a 12-week blinded phase…
  • Abstract Number: 1415 • 2013 ACR/ARHP Annual Meeting

    Safety and Effectiveness Of Abatacept In 3985 Japanese Patients With Rheumatoid Arthritis; Japan All-Cases Post-Marketing Surveillance

    Takao Koike1, Masayoshi Harigai2, Naoki Ishiguro3, Shigeko Inokuma4, Junnosuke Ryu5, Syuji Takei6, Tsutomu Takeuchi7, Y. Tanaka8, Masahiko Watanabe9 and Hisashi Yamanaka10, 1Rheumatology, NTT Sapporo Medical Center, Sapporo, Japan, 2Dept of Pharmacovigilance, Tokyo Medical and Dental University, Tokyo, Japan, 3Orthopaedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan, 4Department of Allergy and Rheumatology diseases, Japanese Red Cross Medical Center, Tokyo, Japan, 5Nihon University School of Medicine, Tokyo, Japan, 6School of Health Sciences, Faculty of Medicine, Kagoshima University, Kagoshima, Japan, 7Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, 8University of Occupational and Environmental Health, Kitakyushu, Japan, 9Bristol-Myers K.K, Tokyo, Japan, 10Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan

    Background/Purpose: A large-scale post-marketing surveillance (PMS) has been implemented to evaluate the safety and effectiveness on the use of intravenous abatacept (ABT) in Japanese patients…
  • Abstract Number: 1216 • 2013 ACR/ARHP Annual Meeting

    Risk Factors Associated With Fracture Occurrence Appear to Differ Between Distal Radius, Clinical Vertebral, and Hip Fractures in Japanese Patients With Rheumatoid Arthritis: A Prospective Observational Cohort Study

    Kensuke Ochi1, Takefumi Furuya1, Yuki Go1, Eisuke Inoue2, Katsunori Ikari1, Atsuo Taniguchi2, Hisashi Yamanaka1 and Shigeki Momohara2, 1Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 2Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan

    Background/Purpose: Patients with rheumatoid arthritis (RA) are at high risk of developing fractures. Previously, utilizing data from our Institute of Rheumatology Rheumatoid Arthritis (IORRA) cohort…
  • Abstract Number: 588 • 2013 ACR/ARHP Annual Meeting

    Efficacy Of Rituximab In Patients With Refractory Lupus Nephritis, a Post-Hoc Analysis From Phase II Trial In Japan

    Yoshiya Tanaka1, Kazuhiko Yamamoto2, Tsutomu Takeuchi3, Nobuyuki Miyasaka4, Takayuki Sumida5, Tsuneyo Mimori6, Takao Koike7 and Kazuhiro Endo8, 1The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, 2Department of Allergy and Rhaumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 3Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, 4Tokyo Medical and Dental University, Tokyo, Japan, 5Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan, 6Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 7Rheumatology, NTT Sapporo Medical Center, Sapporo, Japan, 8Clinical Development, Zenyaku Kogyo Co., Ltd., Tokyo, Japan

    Background/Purpose: B-cell depletion therapy by rituximab has been reported to be useful for treatment of lupus nephritis (LN) in many observational uncontrolled studies, however, placebo-controlled…
  • Abstract Number: 1957 • 2012 ACR/ARHP Annual Meeting

    Prevalence and Associated Factors of Vitamin D Insufficiency and Deficiency in 4,793 Japanese Patients with Rheumatoid Arthritis

    Takefumi Furuya1, Takayuki Hosoi2, Eiichi Tanaka3, Ayako Nakajima4, Atsuo Taniguchi5, Shigeki Momohara1 and Hisashi Yamanaka1, 1Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 2Department of Clinical Research and Development, National Center for Geriatrics and Gerontology, Aichi, Japan, 3Tokyo Women's Medical University, Tokyo, Japan, 4Rheumatology, Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan, 5Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan

    Background/Purpose: Vitamin D (25[OH]D) insufficiency and deficiency is reported to be common in patients with rheumatoid arthritis (RA) and is associated with increased disease activity…
  • Abstract Number: 1312 • 2012 ACR/ARHP Annual Meeting

    Clinical Response At 12 Weeks Predicts Long-Term Remission and the Extent of Radiographic Progression in Japanese Patients with Rheumatoid Arthritis Treated with Certolizumab Pegol with and without Methotrexate Coadministration

    Tsutomu Takeuchi1, Kazuhiko Yamamoto2, Hisashi Yamanaka3, Naoki Ishiguro4, Yoshiya Tanaka5, Katsumi Eguchi6, Akira Watanabe7, Hideki Origasa8, Toshiharu Shoji9, Nobuyuki Miyasaka10 and Takao Koike11, 1Keio University School of Medicine, Tokyo, Japan, 2Department of Allergy & Rheumatology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan, 3Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 4Department of Orthopedic Surgery, Nagoya University, Graduate School & Faculty of Medicine, Nagoya, Aichi, Japan, 5The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, 6Sasebo City General Hospital, Sasebo, Nagasaki, Japan, 7Research Division for Development of Anti-Infectious Agents, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Miyagi, Japan, 8Division of Biostatistics and Clinical Epidemiology, University of Toyama School of Medicine, Toyama, Toyama, Japan, 9Department of Clinical Research and Development, Otsuka Pharmaceutical Co., Ltd, Shinagawa-ku, Tokyo, Japan, 10Department of Medicine and Rheumatology and Global Center of Excellence Program, Tokyo Medical and Dental University, Tokyo, Japan, 11Sapporo medical center NTT EC, Sapporo, Japan

    Background/Purpose: The majority of patients (pts) with active rheumatoid arthritis (RA) have previously been shown to respond during the first 12 weeks (wks)  of certolizumab…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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