Abstracts tagged "Janus kinase (JAK) and pharmacology"

Abstract Number: 1795 • 2013 ACR/ARHP Annual Meeting
An Active Metabolite Contributes To The Pharmacodynamics and Efficacy Of GLPG0634, a Selective JAK1 Inhibitor
Florence Namour, Galapagos SASU, Romainville, France
Background/Purpose: GLPG0634 is an orally-available, selective inhibitor of Janus kinase 1 (JAK1). Through inhibition of signaling pathways for cytokines involved in rheumatoid arthritis (RA), non-selective…

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Abstracts tagged "Janus kinase (JAK) and pharmacology"

An Active Metabolite Contributes To The Pharmacodynamics and Efficacy Of GLPG0634, a Selective JAK1 Inhibitor