Abstracts tagged "Janus kinase (JAK) and Gene Expression"

Abstract Number: 545 • 2019 ACR/ARP Annual Meeting
Molecular Analysis of the Mode of Action of Upadacitinib in Rheumatoid Arthritis Patients: Whole Blood RNA Expression Data from the SELECT-NEXT Study
Samantha Lent ¹, Thierry Sornasse ², Robert Georgantas ¹, Jeremy Sokolove ² and Iain McInnes³, ¹AbbVie, Inc., North Chicago, IL, ²AbbVie Immunology Clinical Development, Redwood City, ³Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom
Background/Purpose: Upadacitinib (UPA), an oral JAK inhibitor selective for JAK1, demonstrated efficacy in patients with moderate-to-severe rheumatoid arthritis (RA) with an inadequate response to conventional…

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Abstracts tagged "Janus kinase (JAK) and Gene Expression"

Molecular Analysis of the Mode of Action of Upadacitinib in Rheumatoid Arthritis Patients: Whole Blood RNA Expression Data from the SELECT-NEXT Study