Abstracts tagged "JAK3"

Abstract Number: 965 • ACR/ARP Annual Meeting 2019
Discovery of DWP212525, a Potent JAK3 and BTK Dual Target Inhibitor for the Treatment of Autoimmune Diseases
Yong Dae Shin¹, Jae-Hun Jung ¹, Eun Kyung Kim ¹, SOHEE IM ¹, Sunah Jun ¹, NamYoun Kim ¹, SeungHwarn Jeong ¹, Hyaejung Hyun ¹ and Joon Seok Park ¹, ¹Daewoong Life science research institute, Yongin-si, Republic of Korea
Background/Purpose: Janus Kinase (JAK) and Bruton's tyrosine kinase (BTK) play critical roles in activation and function of T cells and B cells. Dysregulation of this…