Abstracts tagged "Intracellular trafficking"

Abstract Number: 14 • ACR/ARP Annual Meeting 2019
Sec16A Abnormalities Affect the Intracellular Trafficking of HLA-B27 in the Pathogenesis of Axial Spondyloarthritis
Ayantika Talukdar¹, Fanxing Zeng ², Zhenbo Zhang ¹ and Nigil Haroon ³, ¹University Health Network, Toronto, ON, Canada, ²University Health Network, Toronto, Canada, ³Toronto Western Hospital, Krembil Research Institute, University of Toronto, Toronto, ON, Canada
Background/Purpose: Axial Spondyloarthritis (AxSpA) is a chronic inflammatory arthritis, mainly affecting the axial skeleton. HLA-B27 confers the greatest genetic association in AxSpA. Exome sequencing in…