ACR Meeting Abstracts

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Abstracts tagged "interstitial lung disease"

  • Abstract Number: 288 • 2015 ACR/ARHP Annual Meeting

    Myositis Associated Interstitial Lung Disease: Clinical Predictors of Failure to Conventional Treatment and Their Response to Tacrolimus

    Niharika Sharma1, Anisha Dua1, Michael Putman2, Rekha Vij3 and Mary Strek3, 1Rheumatology, The University of Chicago, Chicago, IL, 2Internal Medicine, The University of Chicago, Chicago, IL, 3Pulmonology, The University of Chicago, Chicago, IL

    Background/Purpose: Interstitial lung disease (ILD) frequently complicates Polymyositis (PM) and Dermatomyositis (DM) and accounts for significant morbidity and mortality in affected patients.  Patients with Myositis…
  • Abstract Number: 2962 • 2015 ACR/ARHP Annual Meeting

    Efficacy of Mycophenolate As a Maintenance Therapy Following the Administration of Cyclophosphamide in the Treatment of Interstitial Lung Disease Associated with Systemic Sclerosis

    Javier Narváez1, Helena Borrell Paños2, Ivan Castellvi3, Sergi Heredia2, Milena Millan3, Susana Herrera4, Eulalia Armengol2, Josep María LLobet3, Joan Miquel Nolla2, María Molina5 and Juan José Alegre6, 1Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 2Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 3Rheumatology Unit. Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, 4Deparment of Pneumology, Hospital Universitario Dr Peset, Valencia, Spain, 5Department of Pneumology, Hospital Universitario de Bellvitge, Barcelona, Spain, 6Rheumatology Department, Hospital Universitario Doctor Peset, Valencia, Spain

    Background/Purpose: Treatment with cyclophosphamide (CYC) for 12 months stabilizes lung function parameters and improves respiratory symptoms of patients with systemic sclerosis and diffuse interstitial lung…
  • Abstract Number: 2998 • 2014 ACR/ARHP Annual Meeting

    Screening for Interstitial Lung Disease in Systemic Sclerosis: Performance of High-Resolution Computed Tomography with Limited Number of Slices – a Prospective Study

    Thomas Frauenfelder1, Anna Winklehner1, Thi Dan Linh Nguyen1, Rucsandra Dobrota2,3, Stephan Baumüller1, Britta Maurer2 and Oliver Distler2, 1Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Zurich, Switzerland, 2Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland, 3Department of Internal Medicine and Rheumatology, Dr.I.Cantacuzino Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania

    Background/Purpose Early diagnosis of interstitial lung disease (ILD), currently the main cause of death in systemic sclerosis (SSc), is needed. The gold standard is high…
  • Abstract Number: 2976 • 2014 ACR/ARHP Annual Meeting

    Lung Ultrasound Screening for Interstitial Lung Disease in Rheumatoid Arthritis. Comparison with Usual Detection Algorithms in Clinical Practice

    Marco Antivalle, Michel Chevallard, Michele Battellino, MariaChiara Ditto, Valentina Varisco, Federica Rigamonti, Alessandra Mutti, Fabiola Atzeni, Alberto Batticciotto and Piercarlo Sarzi-Puttini, Rheumatology, L. Sacco University Hospital, Milano, Italy

    Background/Purpose: interstitial lung disease (RA-ILD) is one of the most serious extraarticular complications of rheumatoid arthritis (RA). Presently, it is not clear which is the…
  • Abstract Number: 2697 • 2014 ACR/ARHP Annual Meeting

    Gender Disparities in Lung Transplantation in Patients with Systemic Sclerosis-Related Interstitial Lung Disease and Pulmonary Hypertension

    Elizabeth Volkmann1, Daniel E. Furst2, Rajeev Saggar3, Philip J. Clements4, Bryant Torres5, Lynne Yoder1 and Rajan Saggar1, 1Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, 2University of California, Los Angeles, CA, 3Cardiothoracic Surgery, University of Arizona College of Medicine, Phoenix, AZ, 4University of California, Los Angeles, Department of Medicine, Los Angeles, CA, 5Health Policy and Management, Rollins School of Public Health, Emory University, Atlanta, GA

    Background/Purpose: Lung transplantation is often the most viable option for patients with severe systemic sclerosis (SSc)-associated interstitial lung disease (ILD) that is unresponsive to pharmacologic…
  • Abstract Number: 2190 • 2014 ACR/ARHP Annual Meeting

    Features of Interstitial Lung Disease Associated with Connective Tissue Disease in a Spanish Southwest Cohort

    Adela Gallego Flores1, Carmen Carrasco Cubero2, Raul Veroz Gonzalez1, Luz Maria Mellado Narciso1, Tamara Libertad Rodriguez Araya1, Juan Jose Aznar Sánchez1 and Eugenio Chamizo Carmona1, 1Rheumatology, Hospital de Mérida, Mérida, Spain, 2Rheumatology, Hospital de Merida, Mérida, Spain

    Background/Purpose Diffuse interstitial lung disease (ILD) can be associated with connective tissue diseases (CTD), and can increase morbidity and mortality significantly. The predominant patterns of…
  • Abstract Number: 1797 • 2014 ACR/ARHP Annual Meeting

    One-Year Survival of Adults with Systemic Sclerosis Following Lung Transplantation: A Nationwide Cohort Study

    Elana J. Bernstein1, Eric R. Peterson2, Joan M. Bathon2 and David J. Lederer2, 1Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, 2Medicine, Columbia University College of Physicians & Surgeons, New York, NY

    Background/Purpose: Lung transplantation is a potentially life-saving treatment for patients with systemic sclerosis (SSc) who have developed end-stage lung disease due to interstitial lung disease…
  • Abstract Number: 1784 • 2014 ACR/ARHP Annual Meeting

    Prognostic Factors for Interstitial Lung Disease with Microscopic Polyangiitis

    Takeshi Shoda, Tohru Takeuchi, Takaaki Ishida, Hideyuki Shiba, Youhei Fujiki, Daisuke Wakura, Shuzo Yoshida, Takuya Kotani, Shigeki Makino and Toshiaki Hanafusa, Department of Internal Medicine (I), Osaka medical college, Osaka, Japan

    Background/Purpose Many patients with interstitial lung disease (ILD) complicated by microscopic polyangiitis (MPA) show a UIP pattern on chest CT. The prognosis is poorer than…
  • Abstract Number: 1685 • 2014 ACR/ARHP Annual Meeting

    Effects of Mycophenolate Mofetil on Pulmonary Lung Function in Interstitial Lung Disease of Systemic Sclerosis

    Michael Pham1 and W Leroy Griffing2, 1Division of Internal Medicine, Mayo Clinic Arizona, Scottsdale, AZ, 2Division of Rheumatology, Mayo Clinic Arizona, Scottsdale, AZ

    Background/Purpose:  Interstitial lung disease remains a primary driver of morbidity and mortality in patients suffering from systemic sclerosis.  Cyclophosphamide currently is the treatment with the…
  • Abstract Number: 1684 • 2014 ACR/ARHP Annual Meeting

    Treatment of Scleroderma Associated Lung Disease with Mycophenolate Mofetil: A Community-Based Study

    Audrey Bearden1, Kent Kwasind Huston2 and Judy Foxworth3, 1Internal Medicine, University of Missouri-Kansas City, Kansas City, MO, 2Rheumatology, The Center for Rheumatic Disease, Kansas City, MO, 3Associate Program Director & Director of Research, The University of Missouri-Kansas City, Kansas City, MO

    Background/Purpose:  Interstitial lung disease occurs in over 80% of patients with scleroderma. Cyclophosphamide is the only treatment proven to benefit scleroderma lung disease in a…
  • Abstract Number: 1698 • 2014 ACR/ARHP Annual Meeting

    Peripheral Blood Eosinophil Counts Increase in Patients with Systemic Sclerosis and Associated with Its Disease Severity

    Tamao Nakashita1, Shinji Motojima2, Katsutoshi Ando3 and Akira Dibatake4, 1Department of Rheumatology and Allergy, Kameda Medical Center, Kamogawa City, Japan, 2[email protected], Kameda Medical Center, Kamogawa City, Japan, 3Depertment of Respiratoly Medicine, Juntendo university, tokyo, Japan, 4Rheumatology and Allergy, Kameda Medical Center, Kamogawa city, Japan

    Background/Purpose : Increased levels of serum pro-fibrotic cytokines such as IL-4 and IL-13 and plasma CXCL4 have been previously reported in patients with systemic sclerosis…
  • Abstract Number: 1682 • 2014 ACR/ARHP Annual Meeting

    Mycophenolate Mofetil Versus Azathioprine in Scleroderma-Associated Interstitial Lung Disease: Results from the Australian Scleroderma Cohort Study

    Claire Owen1, Gene Ngian2, Kathleen Elford2, Owen Moore3, Mandy Nikpour3, Wendy Stevens3, Susanna Proudman4, Janet Roddy5, Jane Zochling6, Catherine Hill7, Peter Nash8, Allan Sturgess9 and Joanne Sahhar2, 1Rheumatology, Monash Health, Melbourne, Australia, 2Monash Health, Melbourne, Australia, 3St Vincent's Hospital, Melbourne, Australia, 4Royal Adelaide Hospital, Adelaide, Australia, 5Royal Perth Hospital, Perth, Australia, 6Department of Rheumatology, Menzies Research Institute Tasmania, Hobart, TAS, Australia, 7Queen Elizabeth Hospital, Adelaide, Australia, 8Sunshine Coast Rheumatology, Maroochydore, Australia, 9The St George Hospital, Sydney, Australia

    Background/Purpose: Systemic sclerosis-associated interstitial lung disease (SSc-ILD) is common and when progressive, associated with significant morbidity and mortality. Cyclophosphamide is frequently used as first line…
  • Abstract Number: 1433 • 2014 ACR/ARHP Annual Meeting

    Clinical Characterization of Subclinical Rheumatoid Arthritis-Associated Interstitial Lung Disease

    Masaomi Yamasaki, Rheumatology, Shin-Yokohama Yamasaki Clinic, Yokohama, Japan

    Background/Purpose Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is a common manifestation of rheumatoid lung disease.  Subclinical RA-ILD is most commonly identified on HRCT imaging. In…
  • Abstract Number: 1419 • 2014 ACR/ARHP Annual Meeting

    Rituximab Use in Patients with Rheumatoid Arthritis-Associated Interstitial Lung Disease and Other Connective Tissue Disease-Associated Interstitial Lung Disease: A Single Center Experience

    Sandra Chartrand1,2, Jeffery J. Swigris3, Lina Peykova2 and Aryeh Fischer4, 1Rheumatology, Hôpital Maisonneuve-Rosemont, Montreal, QC, Canada, 2Rheumatology, National Jewish Health, Denver, CO, 3Autoimmune Lung Center, National Jewish Health, Denver, CO, 4Rheumatology / ILD Program, National Jewish Health, Denver, CO

    Background/Purpose: Small series have suggested that rituximab (RTX) may be effective as rescue-therapy for connective tissue disease-associated interstitial lung disease (CTD-ILD). We sought to describe…
  • Abstract Number: 1273 • 2014 ACR/ARHP Annual Meeting

    Assessment of the Effect of Rituximab in the Treatment of Interstitial Lung Disease  associated with the Antisynthetase Syndrome

    Tracy Doyle1, Juan Osorio2, Eduarda Nilo DeMagaldi3, Rachna Madan4, Fernanda Cabral5, Ivan Rosas2 and Paul Dellaripa6, 1Division of pulmonary medicine, Brigham and Women's Hospital, Boston, MA, 2Division of pulmonary medicine, Brigham and Women's Hospital, Boston, MA, 3medicine, Harvard Medical School, Boston, MA, 4Radiology, Brigham and women's Hospital, Boston, MA, 5Radiiology, Brigham and women's Hospital, boston, MA, 6Division of Rheumatology, Brigham and Women's Hospital, Boston, MA

    Background/purpose: To assess clinical outcomes including pulmonary function and radiographic imaging in patients with ILD and the antisynthetase syndrome who were treated with Rituxan (RTX)Methods:…
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