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Abstracts tagged "interstitial lung disease"

  • Abstract Number: 1569 • 2015 ACR/ARHP Annual Meeting

    Rituximab Efficacy in the Treatment of Diffuse Interstitial Lung Disease Associated with Rheumatoid Arthritis

    Javier Narváez1, Milagros Ricse2, Juan José Alegre3, Gloria Albert Espi3, Carmen Gomez Vaquero4, Helena Borrell Paños2, Eulalia Armengol2, Joan Miquel Nolla2, Susana Herrera5 and Maria Molina6, 1Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 2Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 3Rheumatology Department, Hospital Universitario Doctor Peset, Valencia, Spain, 4Department of Rheumatology, Hospital Universitario Bellvitge, Barcelona, Spain, 5Deparment of Pneumology, Hospital Universitario Dr Peset, Valencia, Spain, 6Department of Pneumology, Hospital Universitario de Bellvitge, Barcelona, Spain

    Background/Purpose: To investigate the efficacy and safety of rituximab (RTX) in the the management of progressive rheumatoid arthritis related interstitial lung disease (RA-ILD). Methods: An…
  • Abstract Number: 1583 • 2015 ACR/ARHP Annual Meeting

    Identifying Risk Factors for Progression of Rheumatoid Arthritis-Associated Interstitial Lung Disease

    Yashaar Chaichian1, Dina Bassiri2, Imre Noth3, Mary Strek3, Tammy Utset1 and Rekha Vij3, 1Medicine, Section of Rheumatology, University of Chicago Medical Center, Chicago, IL, 2Statistical & Applied Research, ACT, Inc., Iowa City, IA, 3Medicine, Section of Pulmonary/Critical Care, University of Chicago Medical Center, Chicago, IL

    Background/Purpose: Interstitial lung disease (ILD) is recognized as a frequent extra-articular manifestation of rheumatoid arthritis (RA) associated with significant morbidity and mortality. Nevertheless, risk factors…
  • Abstract Number: 1698 • 2014 ACR/ARHP Annual Meeting

    Peripheral Blood Eosinophil Counts Increase in Patients with Systemic Sclerosis and Associated with Its Disease Severity

    Tamao Nakashita1, Shinji Motojima2, Katsutoshi Ando3 and Akira Dibatake4, 1Department of Rheumatology and Allergy, Kameda Medical Center, Kamogawa City, Japan, 2[email protected], Kameda Medical Center, Kamogawa City, Japan, 3Depertment of Respiratoly Medicine, Juntendo university, tokyo, Japan, 4Rheumatology and Allergy, Kameda Medical Center, Kamogawa city, Japan

    Background/Purpose : Increased levels of serum pro-fibrotic cytokines such as IL-4 and IL-13 and plasma CXCL4 have been previously reported in patients with systemic sclerosis…
  • Abstract Number: 1682 • 2014 ACR/ARHP Annual Meeting

    Mycophenolate Mofetil Versus Azathioprine in Scleroderma-Associated Interstitial Lung Disease: Results from the Australian Scleroderma Cohort Study

    Claire Owen1, Gene Ngian2, Kathleen Elford2, Owen Moore3, Mandy Nikpour3, Wendy Stevens3, Susanna Proudman4, Janet Roddy5, Jane Zochling6, Catherine Hill7, Peter Nash8, Allan Sturgess9 and Joanne Sahhar2, 1Rheumatology, Monash Health, Melbourne, Australia, 2Monash Health, Melbourne, Australia, 3St Vincent's Hospital, Melbourne, Australia, 4Royal Adelaide Hospital, Adelaide, Australia, 5Royal Perth Hospital, Perth, Australia, 6Department of Rheumatology, Menzies Research Institute Tasmania, Hobart, TAS, Australia, 7Queen Elizabeth Hospital, Adelaide, Australia, 8Sunshine Coast Rheumatology, Maroochydore, Australia, 9The St George Hospital, Sydney, Australia

    Background/Purpose: Systemic sclerosis-associated interstitial lung disease (SSc-ILD) is common and when progressive, associated with significant morbidity and mortality. Cyclophosphamide is frequently used as first line…
  • Abstract Number: 1433 • 2014 ACR/ARHP Annual Meeting

    Clinical Characterization of Subclinical Rheumatoid Arthritis-Associated Interstitial Lung Disease

    Masaomi Yamasaki, Rheumatology, Shin-Yokohama Yamasaki Clinic, Yokohama, Japan

    Background/Purpose Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is a common manifestation of rheumatoid lung disease.  Subclinical RA-ILD is most commonly identified on HRCT imaging. In…
  • Abstract Number: 1419 • 2014 ACR/ARHP Annual Meeting

    Rituximab Use in Patients with Rheumatoid Arthritis-Associated Interstitial Lung Disease and Other Connective Tissue Disease-Associated Interstitial Lung Disease: A Single Center Experience

    Sandra Chartrand1,2, Jeffery J. Swigris3, Lina Peykova2 and Aryeh Fischer4, 1Rheumatology, Hôpital Maisonneuve-Rosemont, Montreal, QC, Canada, 2Rheumatology, National Jewish Health, Denver, CO, 3Autoimmune Lung Center, National Jewish Health, Denver, CO, 4Rheumatology / ILD Program, National Jewish Health, Denver, CO

    Background/Purpose: Small series have suggested that rituximab (RTX) may be effective as rescue-therapy for connective tissue disease-associated interstitial lung disease (CTD-ILD). We sought to describe…
  • Abstract Number: 1273 • 2014 ACR/ARHP Annual Meeting

    Assessment of the Effect of Rituximab in the Treatment of Interstitial Lung Disease  associated with the Antisynthetase Syndrome

    Tracy Doyle1, Juan Osorio2, Eduarda Nilo DeMagaldi3, Rachna Madan4, Fernanda Cabral5, Ivan Rosas2 and Paul Dellaripa6, 1Division of pulmonary medicine, Brigham and Women's Hospital, Boston, MA, 2Division of pulmonary medicine, Brigham and Women's Hospital, Boston, MA, 3medicine, Harvard Medical School, Boston, MA, 4Radiology, Brigham and women's Hospital, Boston, MA, 5Radiiology, Brigham and women's Hospital, boston, MA, 6Division of Rheumatology, Brigham and Women's Hospital, Boston, MA

    Background/purpose: To assess clinical outcomes including pulmonary function and radiographic imaging in patients with ILD and the antisynthetase syndrome who were treated with Rituxan (RTX)Methods:…
  • Abstract Number: 1272 • 2014 ACR/ARHP Annual Meeting

    Myositis-Specific and Myositis Associated Autoantibodies in Indian Patients with Inflammatory Myositis

    Puja Srivastava, Ramnath Misra, Able Lawrence, Amita Aggarwal and Vikas Agarwal, Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India

    Background/Purpose Recently, idiopathic inflammatory myositis (IIM) has been categorised into distinct subsets based on myositis specific autoantibodies (MSA) and myositis associated autoantibodies (MAA). However, there is…
  • Abstract Number: 432 • 2014 ACR/ARHP Annual Meeting

    Rheumatoid Arthritis-Associated Interstitial Lung Disease: Risk Factors for Disease Progression

    Yashaar Chaichian1, Imre Noth1, Mary Strek1, Tammy O. Utset2 and Rekha Vij1, 1University of Chicago Medical Center, Chicago, IL, 2University of Chicago, Chicago, IL

    Background/Purpose Rheumatoid arthritis (RA) is the most common systemic connective tissue disease in the U.S. Interstitial lung disease (ILD) is a frequent extra-articular manifestation of…
  • Abstract Number: 2998 • 2014 ACR/ARHP Annual Meeting

    Screening for Interstitial Lung Disease in Systemic Sclerosis: Performance of High-Resolution Computed Tomography with Limited Number of Slices – a Prospective Study

    Thomas Frauenfelder1, Anna Winklehner1, Thi Dan Linh Nguyen1, Rucsandra Dobrota2,3, Stephan Baumüller1, Britta Maurer2 and Oliver Distler2, 1Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Zurich, Switzerland, 2Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland, 3Department of Internal Medicine and Rheumatology, Dr.I.Cantacuzino Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania

    Background/Purpose Early diagnosis of interstitial lung disease (ILD), currently the main cause of death in systemic sclerosis (SSc), is needed. The gold standard is high…
  • Abstract Number: 2976 • 2014 ACR/ARHP Annual Meeting

    Lung Ultrasound Screening for Interstitial Lung Disease in Rheumatoid Arthritis. Comparison with Usual Detection Algorithms in Clinical Practice

    Marco Antivalle, Michel Chevallard, Michele Battellino, MariaChiara Ditto, Valentina Varisco, Federica Rigamonti, Alessandra Mutti, Fabiola Atzeni, Alberto Batticciotto and Piercarlo Sarzi-Puttini, Rheumatology, L. Sacco University Hospital, Milano, Italy

    Background/Purpose: interstitial lung disease (RA-ILD) is one of the most serious extraarticular complications of rheumatoid arthritis (RA). Presently, it is not clear which is the…
  • Abstract Number: 2697 • 2014 ACR/ARHP Annual Meeting

    Gender Disparities in Lung Transplantation in Patients with Systemic Sclerosis-Related Interstitial Lung Disease and Pulmonary Hypertension

    Elizabeth Volkmann1, Daniel E. Furst2, Rajeev Saggar3, Philip J. Clements4, Bryant Torres5, Lynne Yoder1 and Rajan Saggar1, 1Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, 2University of California, Los Angeles, CA, 3Cardiothoracic Surgery, University of Arizona College of Medicine, Phoenix, AZ, 4University of California, Los Angeles, Department of Medicine, Los Angeles, CA, 5Health Policy and Management, Rollins School of Public Health, Emory University, Atlanta, GA

    Background/Purpose: Lung transplantation is often the most viable option for patients with severe systemic sclerosis (SSc)-associated interstitial lung disease (ILD) that is unresponsive to pharmacologic…
  • Abstract Number: 2190 • 2014 ACR/ARHP Annual Meeting

    Features of Interstitial Lung Disease Associated with Connective Tissue Disease in a Spanish Southwest Cohort

    Adela Gallego Flores1, Carmen Carrasco Cubero2, Raul Veroz Gonzalez1, Luz Maria Mellado Narciso1, Tamara Libertad Rodriguez Araya1, Juan Jose Aznar Sánchez1 and Eugenio Chamizo Carmona1, 1Rheumatology, Hospital de Mérida, Mérida, Spain, 2Rheumatology, Hospital de Merida, Mérida, Spain

    Background/Purpose Diffuse interstitial lung disease (ILD) can be associated with connective tissue diseases (CTD), and can increase morbidity and mortality significantly. The predominant patterns of…
  • Abstract Number: 1797 • 2014 ACR/ARHP Annual Meeting

    One-Year Survival of Adults with Systemic Sclerosis Following Lung Transplantation: A Nationwide Cohort Study

    Elana J. Bernstein1, Eric R. Peterson2, Joan M. Bathon2 and David J. Lederer2, 1Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, 2Medicine, Columbia University College of Physicians & Surgeons, New York, NY

    Background/Purpose: Lung transplantation is a potentially life-saving treatment for patients with systemic sclerosis (SSc) who have developed end-stage lung disease due to interstitial lung disease…
  • Abstract Number: 1784 • 2014 ACR/ARHP Annual Meeting

    Prognostic Factors for Interstitial Lung Disease with Microscopic Polyangiitis

    Takeshi Shoda, Tohru Takeuchi, Takaaki Ishida, Hideyuki Shiba, Youhei Fujiki, Daisuke Wakura, Shuzo Yoshida, Takuya Kotani, Shigeki Makino and Toshiaki Hanafusa, Department of Internal Medicine (I), Osaka medical college, Osaka, Japan

    Background/Purpose Many patients with interstitial lung disease (ILD) complicated by microscopic polyangiitis (MPA) show a UIP pattern on chest CT. The prognosis is poorer than…
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