Abstracts tagged "Interleukins (IL) and signal transduction"

Abstract Number: 736 • ACR/ARHP Annual Meeting 2012
Inhibition of Interleukin-17 Signaling Via De-Ubiquitinatio
Sarah L. Gaffen¹ and Abhishek Garg², ¹Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ²Rheumatology/Clinical Immun, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: IL-17A (IL-17) is a proinflammatory cytokine that contributes to the pathogenesis of various autoimmune diseases, including rheumatoid arthritis (RA), multiple sclerosis (MS) and psoriasis.…