ACR Meeting Abstracts

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Abstracts tagged "interleukins (IL) and regulatory cells"

  • Abstract Number: 2683 • 2018 ACR/ARHP Annual Meeting

    Selective Expansion and Targeting of FoxP3+CD127lo Regulatory T Cells By Low-Dose IL-2 Therapy in Active SLE

    Jens Humrich1, Caroline von Spee-Mayer2, Philipp Enghard3, Angelika Rose4, Elise Siegert5, Tobias Alexander5, Falk Hiepe6, Gerd R. Burmester7 and Gabriela Riemekasten8, 1Department of Rheumatology, University Hospital Schleswig-Holstein - Campus Lübeck, Lübeck, Germany, 2Immunology, University Hospital Freiburg, Freiburg, Germany, 3Department of Nephrology, Charité – University Medicine Berlin, Berlin, Germany, 4Rheumatology and Clinical Immunology, Charité – University Medicine Berlin, Berlin, Germany, 5Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, Berlin, Germany, 6Rheumatology, Charité – University Medicine Berlin, Berlin, Germany, 7Rheumatology and Clinical Immunology, Charité-University Medicine Berlin, Berlin, Germany, 8Rheumatology, University Hospital Schleswig-Holstein - Campus Lübeck, Lübeck, Germany

    Background/Purpose: Interleukin-2 (IL-2) is crucial for the growth and survival of regulatory T cells (Treg), and thus for the control of autoimmunity. In previous studies…
  • Abstract Number: 2014 • 2015 ACR/ARHP Annual Meeting

    Deficiency of IL-27 Exacerbate Sjögren’s Syndrome through Inhibiting Differentiation of Type 1 Regulatory T Cells

    Genhong Yao1, Bingyu Shi1, Jingjing Qi1, Ying Wang1, Weiwei Chen1, Xiaojun Tang1, Dandan Wang2, Xuebing Feng1 and Lingyun Sun1, 1Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China, 2Department of Rheumatology and immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China

    Background/Purpose: Sjögren's Syndrome (SS) is a systemic autoimmune disease characterized by chronic inflammation involving the exocrine glands, particularly the salivary and lacrimal glands. The pathogenesis…
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ACR Pediatric Rheumatology Symposium 2020

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