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Abstracts tagged "interleukins (IL) and radiography"

  • Abstract Number: 670 • ACR/ARHP Annual Meeting 2018

    Low Rate of Spinal Radiographic Progression over 2 Years in Ankylosing Spondylitis Patients Treated with Secukinumab: A Historical Cohort Comparison

    Jürgen Braun1, Hildrun Haibel2, Manouk de Hooge3, Robert B.M. Landewé4, Martin Rudwaleit5, Todd Fox6, Aimee Readie7, Hanno Richards6, Brian Porter8, Ruvie Martin7, Denis Poddubnyy9, Joachim Sieper10 and Désirée van der Heijde11, 1Rheumazentrum Ruhrgebiet, Herne, Germany, 2Charité Universitätmedizin Berlin, Berlin, Germany, 3Leiden University Medical Center, Leiden, Netherlands, 4Maastricht Univ Medical Center, Maastricht, Netherlands, 5Internal Medicine and Rheumatology, Klinikum Bielefeld Rosenhöhe, Bielefeld, Germany, 6Novartis Pharma AG, Basel, Switzerland, 7Novartis Pharmaceuticals Corporation, East Hanover, NJ, 8Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA, East Hanover, NJ, 9Charité Universitätsmedizin Berlin, Berlin, Germany, 10Charité Universitätsmeidzin Berlin, Berlin, Germany, 11Leiden University Medical Centre, Leiden, Netherlands

    Background/Purpose: Secukinumab, a fully human monoclonal antibody that neutralizes IL-17A, improved signs and symptoms of ankylosing spondylitis (AS) in patients (pts) in the MEASURE 1…

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