Abstracts tagged "interferons and transcription factor"

Abstract Number: 300 • 2017 ACR/ARHP Annual Meeting
The DNA-Binding Protein ARID3a Is Associated with Interferon Alpha Production in Lupus Patient Plasmacytoid Dendritic Cells and Neutrophils
Michelle Ratliff¹, Joshua Garton^1,2, Indra Adrianto³, Ambra Pastori⁴, Courtney Montgomery⁵, Patrick Gaffney⁴, Judith A. James^3,6 and Carol Webb^1,7,8, ¹Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ²Chemistry, University of Oklahoma, Oklahoma City, OK, ³Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁴Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁵Arthritis & Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁶Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁷Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁸Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK
Background/Purpose: We previously demonstrated over-expression of the DNA-binding protein ARID3a in peripheral blood B lymphocytes from patients with systemic lupus erythematosus (SLE) compared to healthy…

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