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Abstracts tagged "interferons and prolactin"

  • Abstract Number: 1660 • ACR/ARHP Annual Meeting 2017

    Prolactin Induces an Interferon Signature in Monocytes and Drives IRF1-HAT Interactions

    Yiu Tak Leung1, Lihua Shi2, Kelly Maurer2, Li Song3 and Kathleen E. Sullivan4, 1Temple University, Philadelphia, PA, 2Immunology ARC 1216, The Children's Hospital of Philadelphia, Philadelphia, PA, 3Allergy Immunology, Children's Hospital of Philadelphia, Philadelphia, PA, 4Pediatrics, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Epigenetic changes in systemic lupus erythematosus (SLE) offer a potential explanation for the chronicity of disease. We previously found that interferon regulatory factor-1(IRF1) binding…

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