Abstracts tagged "Interferons and osteopontin"

Abstract Number: 2281 • 2012 ACR/ARHP Annual Meeting
Tartrate-Resistant Acid Phosphatase Deficiency in the Predisposition to Systemic Lupus Erythematosus
Jie An¹, Tracy A. Briggs², Nalini Agrawal³, Alice Wiedeman⁴, Laurence Chaperot⁵, Joel Plumas⁵, Yanick J. Crow² and Keith B. Elkon⁶, ¹Division of Rheumatology, Department of Medicine & Immunology, University of Washington, Seattle, WA, ²Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom, ³Rheumatology, University of Washington, Seattle, WA, ⁴Department of Immunology, University of Washington, Seattle, WA, ⁵Inserm U823/Ujf/EFS, Immunobiology & Immunotherapy of Cancers, La Tronche, France, ⁶Rheumatology Box 356428, University of Washington, Seattle, WA
Background/Purpose: The enzyme tartrate-resistant acid phosphatase (TRAP) is highly expressed in osteoclasts. One of the main substrates for TRAP in bone matrix is osteopontin (OPN). …

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Abstracts tagged "Interferons and osteopontin"

Tartrate-Resistant Acid Phosphatase Deficiency in the Predisposition to Systemic Lupus Erythematosus