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Abstracts tagged "interferons and neonatal disorders"

  • Abstract Number: 941 • ACR/ARHP Annual Meeting 2017

    Ro/SSA Autoantibody Exposed Neonates Have an Expansion of NK Cells and a Discernible Type II IFN Signature with High IFNγ in Peripheral Blood

    Margarita Ivanchenko1, Malin Hedlund1, Gudny Ella Thorlacius1, Vijole Ottosson1, Karine Chemin2, Sven-Erik Sonesson3 and Marie Wahren-Herlenius1, 1Unit of Experimental Rheumatology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, Stockholm, Sweden, 2Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, Stockholm, Sweden, 3Pediatric Cardiology Unit, Department of Women´s and Children´s Health, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, Stockholm, Sweden

    Background/Purpose: Congenital heart block (CHB) may develop in the fetus of women with Ro/SSA autoantibodies. The mothers are commonly diagnosed with Sjögren’s syndrome or SLE.…

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