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Abstracts tagged "interferons and metabolomics"

  • Abstract Number: 1079 • ACR/ARHP Annual Meeting 2018

    Plasma Metabolomic Analysis Combined with Transcriptome Data Has Revealed the Importance of Amino Acids Homeostasis in SLE Pathogenesis

    Yukiko Iwasaki1, Yusuke Takeshima1,2, Mineto Ota1,2, Yasuo Nagafuchi1, Shuji Sumitomo1, Akari Suzuki3, Yuta Kochi3, Tomohisa Okamura1,2, Ichirou Miki4, Kazuhiro Sakurada4, Shigeo Koyasu4, Kazuhiko Yamamoto1,3 and Keishi Fujio1, 1Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 2Department of Functional Genomics and Immunological Diseases, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan, 3Laboratory for Autoimmune Diseases, Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan, 4Medical Sciences Innovation Hub Program, Cluster for Science and Technology Hub, RIKEN, Yokohama, Japan

    Background/Purpose: Recently, many reports on immune metabolism have been accumulated and metabolic changes are now considered to be a key factor for controlling immune cell…

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