Abstracts tagged "interferons and metabolomics"

Abstract Number: 1079 • 2018 ACR/ARHP Annual Meeting
Plasma Metabolomic Analysis Combined with Transcriptome Data Has Revealed the Importance of Amino Acids Homeostasis in SLE Pathogenesis
Yukiko Iwasaki¹, Yusuke Takeshima^1,2, Mineto Ota^1,2, Yasuo Nagafuchi¹, Shuji Sumitomo¹, Akari Suzuki³, Yuta Kochi³, Tomohisa Okamura^1,2, Ichirou Miki⁴, Kazuhiro Sakurada⁴, Shigeo Koyasu⁴, Kazuhiko Yamamoto^1,3 and Keishi Fujio¹, ¹Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, ²Department of Functional Genomics and Immunological Diseases, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan, ³Laboratory for Autoimmune Diseases, Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan, ⁴Medical Sciences Innovation Hub Program, Cluster for Science and Technology Hub, RIKEN, Yokohama, Japan
Background/Purpose: Recently, many reports on immune metabolism have been accumulated and metabolic changes are now considered to be a key factor for controlling immune cell…

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