Abstracts tagged "interferons and interstitial lung disease"

Abstract Number: 754 • 2017 ACR/ARHP Annual Meeting
Interferon Siganture in Systemic Sclerosis Lung Microvascular Endothelial Cells
Fabian A Mendoza¹, Sonsoles Piera-Velazquez², Peter J. Wermuth³, Sankar Addya⁴, Carol A. Feghali-Bostwick⁵ and Sergio A. Jimenez⁶, ¹Rheumatology Division, Department of Medicine, Thomas Jefferson University, Jefferson Institute of Molecular Medicine and Scleroderma Center, Thomas Jefferson University, Philadelphia, PA, ²Jefferson Institute of Molecular Medicine and Scleroderma Center., Thomas Jefferson University, Philadelphia, PA, ³Jefferson Institute of Molecular Medicine, Division of Connective Tissue Diseases and Scleroderma Center, Thomas Jefferson University, Philadelphia, PA, ⁴Kimmel Cancer Center, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, ⁵Division of Rheumatology and Immunology, Medical University of South Carolina, Charleston, SC, ⁶Scleroderma Center and Jefferson Institute of Molecular Medicine, Thomas Jefferson Univ, Philadelphia, PA
Background/Purpose: Systemic Sclerosis (SSc) is characterized by severe fibroproliferative vasculopathy, exaggerated deposition of extracellular matrix molecules (ECM) in skin and multiple internal organs, and alterations…

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