Abstracts tagged "Integrins and osteoclasts"

Abstract Number: 2081 • 2012 ACR/ARHP Annual Meeting
Avβ3 Integrin Inhibition with Cilengitide Both Prevents and Treats Collagen Induced Arthritis
Despoina Sykoutri¹, Nisha Geetha², Silvia Hayer³, Peter Mandl¹, Josef S. Smolen⁴, Gerald Prager² and Kurt Redlich³, ¹Rheumatology, Medical University of Vienna, Vienna, Austria, ²Oncology, Medical University of Vienna, Vienna, Austria, ³Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ⁴Rheumatologie, Medical University of Vienna and Hietzing Hospital, Vienna, Austria
Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial inflammation and osteoclast (OC) mediated bone erosions. AlphaVbeta3 (αvβ3) integrin is highly expressed…

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Abstracts tagged "Integrins and osteoclasts"

Avβ3 Integrin Inhibition with Cilengitide Both Prevents and Treats Collagen Induced Arthritis