Abstracts tagged "integrins and osteoclastogenesis"

Abstract Number: 33 • 2012 ACR/ARHP Annual Meeting
Novel Targets for Blocking Osteoclast-Mediated Resorption in Inflammatory Disorders
Kevin P. McHugh¹, Tania N. Crotti¹, Jun Li², Jon Hill³, Gerald H. Nabozny², Steven R. Goldring⁴ and P. Edward Purdue⁵, ¹Orthopedic Surgery, Center for Advanced Orthopedic Studies, Beth Israel Deaconess Medical Center, Boston, MA, ²Immunology and Inflammation, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, ³Scientific Knowledge Discovery, Boehringer Ingelheim Pharmaceuticals Inc, Ridgefield, CT, ⁴Hospital for Special Surgery, New York, NY, ⁵Hospital for Special Surgery, Weill Cornell Medical Center, New York, NY
Background/Purpose: Osteoclasts are specialized myeloid lineage cells that mediate both pathologic and physiologic bone remodeling Fully differentiated and functional osteoclasts are found exclusively associated with…

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Abstracts tagged "integrins and osteoclastogenesis"

Novel Targets for Blocking Osteoclast-Mediated Resorption in Inflammatory Disorders