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Abstracts tagged "Integrated Summary of Safety"

  • Abstract Number: 509 • ACR/ARP Annual Meeting 2019

    Safety Profile of Upadacitinib in Rheumatoid Arthritis: Integrated Analysis from the SELECT Phase 3 Clinical Program

    Stanley Cohen1, Ronald van Vollenhoven 2, Kevin Winthrop 3, Cristiano A. Zerbini 4, Yoshiya Tanaka 5, Louis Bessette 6, Ying Zhang 7, Nasser Khan 8, Barbara Hendrickson 7, Jose Jeffrey Enejosa 7 and Gerd Burmester 9, 1Metroplex Clinical Research Center, Dallas, TX, 2Amsterdam Rheumatology and Immunology Center, Amsterdam, Netherlands, 3Oregon Health and Science University, Portland, OR, 4Centro Paulista de Investigação Clinica, São Paulo, Brazil, 5University of Occupational and Environmental Health Japan, Kitakyushu, Japan, 6Laval University, Quebec City, QC, Canada, 7AbbVie Inc., North Chicago, IL, USA, North Chicago, IL, 8Abbvie Inc, North Chicago, IL, 9Charité—University Medicine Berlin, Berlin, Germany

    Background/Purpose: Upadacitinib (UPA), an oral JAK1-selective inhibitor, was evaluated in a comprehensive clinical program of 5 pivotal Phase 3 randomized-controlled trials (RCTs) across the full…

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