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Abstracts tagged "integrated safety"

  • Abstract Number: 1698 • ACR Convergence 2021

    Integrated Safety Analysis Update for Filgotinib in Patients with Moderately to Severely Active Rheumatoid Arthritis Receiving Treatment over a Median of 2.2 Years

    Kevin Winthrop1, Yoshiya Tanaka2, Tsutomu Takeuchi3, Alan Kivitz4, Mark Genovese5, Alena Pechonkina6, Franziska Matzkies6, Beatrix Bartok7, Kun Chen6, Deyuan Jiang6, Iyabode Tiamiyu6, Robin Besuyen8, Sander Strengholt9, Gerd Burmester10 and Jacques-Eric Gottenberg11, 1Oregon Health & Science University, Portland, OR, 2University of Occupational and Environmental Health, Kitakyushu, Japan, 3Div. Rheumatology, Keio University, Tokyo, Japan, 4Altoona Center for Clinical Research, Duncansville, PA, 5Gilead Sciences, Inc., Sunnyvale, CA, 6Gilead Sciences, Inc., Foster City, CA, 7Gilead Sciences, Inc., La Jolla, CA, 8Galapagos BV, Leiden, Netherlands, 9Galapagos, BV, New York, NY, 10Charité University Medicine Berlin, Berlin, Germany, 11National Reference Center for Rare East South-West Autoimmune Systemic Diseases RESO, Strasbourg University Hospitals, Strasbourg, France

    Background/Purpose: The preferential Janus kinase (JAK)-1 inhibitor filgotinib (FIL) significantly improved signs and symptoms of RA in Phase 2 and 3 trials,1–5 and FIL is…

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