Abstracts tagged "insulin-like growth factor and osteoarthritis"

Abstract Number: 982 • 2012 ACR/ARHP Annual Meeting
Genetic Variants near Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) Are Associated with Hip Osteoarthritis
Daniel S. Evans¹, Neeta Parimi¹, Ana M. Valdes², Hanneke J.M Kerkhof³, Frederic Cailotto⁴, Michael C. Nevitt⁵, Steven R. Cummings¹, Rik J. Lories⁶, Timothy D. Spector⁷, Nigel K. Arden⁸, Joyce B. van Meurs³ and Nancy E. Lane⁹, ¹California Pacific Medical Center Research Institute, San Francisco, CA, ²Department of Twin Research and Genetic Epidemiology, Dept of Twin Research and Genetic Epidemiology, St. Thomas' Hospital, King's College London, London, United Kingdom, ³Department of Internal Medicine, Erasmus Medical Center and The Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging, Rotterdam, Netherlands, ⁴Laboratory for Skeletal Development and Joint Disorders, Department of Development and Regeneration, KU Leuven, Leuven, Belgium, ⁵Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ⁶Dept of Development and Regeneration, Laboratory for Skeletal Development and Joint Disorders, KU Leuven, Leuven, Belgium, ⁷Dept of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom, ⁸NDORMS; MRC Lifecourse Epidemiology Unit, Oxford NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, United Kingdom, ⁹Internal Medicine, Center for Musculoskeletal Health, UC Davis School of Medicine, Sacramento, CA
Background/Purpose: Hip osteoarthritis (HOA) is one of the most common joint disorders and can result in pain and disability. HOA is heritable, but the particular…

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