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Abstracts tagged "innate immunity and systemic lupus erythematosus (SLE)"

  • Abstract Number: 1820 • ACR/ARHP Annual Meeting 2016

    Dectin-1 on Monocytic Cells Mediates Aberrant Innate and Adaptive Immune Responses in Patients with Systemic Lupus Erythematosus

    Mo Yin Mok, Ian Lam, Daniel Luk, Yi Lo and Wai Kin Chan, Department of Medicine, University of Hong Kong, Hong Kong, Hong Kong

    Background/Purpose: Dectin-1 is a c-type lectin like receptor that signals via syk and is involved in anti-fungal immunity. Dectin-1 was found to trigger experimental inflammatory…
  • Abstract Number: 198 • ACR/ARHP Annual Meeting 2015

    CL-L1 and CL-K1 Complement Associated Pattern Recognition Molecules in Systemic Lupus Erythematosus

    Anne Troldborg1, Steffen Thiel2, Lisbeth Jensen3, Magdalena Janina Laska2, Søren Hansen4, Bent Deleuran5,6, Jens Christian Jensenius2 and Kristian Stengaard-Pedersen5, 1clinical medicine, Aarhus University, Aarhus, Denmark, 2Biomedicine, Aarhus University, Aarhus, Denmark, 3Biomedicin, Aarhus University, Aarhus, Denmark, 4Department of cancer and inflammation research, University of Southern Denmark, Odense, Denmark, 5Rheumatology, Aarhus University Hospital, Aarhus, Denmark, 6Biomedicin, Aarhus University, 8000, Denmark

    Background/Purpose: The complement system is one of the key players in the pathogenesis of systemic lupus erythematosus (SLE). Collectin liver 1 (CL-L1) and collectin kidney…
  • Abstract Number: 1200 • ACR/ARHP Annual Meeting 2014

    Plasma Levels of Pattern Recognition Molecules of the Lectin Pathway Are Altered in SLE Patients

    Anne Troldborg1,2, Steffen Thiel3, Magdalena Janina Laska3, Bent Deleuran4,5, Jens Christian Jensenius3 and Kristian Stengaard-Pedersen2,6, 1clinical medicine, Aarhus University, Aarhus, Denmark, 2Rheumatology, Aarhus University Hospital, Aarhus, Denmark, 3Biomedicine, Aarhus University, Aarhus, Denmark, 4Department of Biomedicine, Aarhus University, Aarhus, Denmark, 5Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, 6Clinical medicine, Aarhus University, Aarhus, Denmark

    Background/Purpose Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease where the Complement System plays a key role in the pathogenesis. The objective of this…

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