Abstracts tagged "innate immunity and systemic lupus erythematosus (SLE)"

Abstract Number: 1820 • 2016 ACR/ARHP Annual Meeting
Dectin-1 on Monocytic Cells Mediates Aberrant Innate and Adaptive Immune Responses in Patients with Systemic Lupus Erythematosus
Mo Yin Mok, Ian Lam, Daniel Luk, Yi Lo and Wai Kin Chan, Department of Medicine, University of Hong Kong, Hong Kong, Hong Kong
Background/Purpose: Dectin-1 is a c-type lectin like receptor that signals via syk and is involved in anti-fungal immunity. Dectin-1 was found to trigger experimental inflammatory…
Abstract Number: 198 • 2015 ACR/ARHP Annual Meeting
CL-L1 and CL-K1 Complement Associated Pattern Recognition Molecules in Systemic Lupus Erythematosus
Anne Troldborg¹, Steffen Thiel², Lisbeth Jensen³, Magdalena Janina Laska², Søren Hansen⁴, Bent Deleuran^5,6, Jens Christian Jensenius² and Kristian Stengaard-Pedersen⁵, ¹clinical medicine, Aarhus University, Aarhus, Denmark, ²Biomedicine, Aarhus University, Aarhus, Denmark, ³Biomedicin, Aarhus University, Aarhus, Denmark, ⁴Department of cancer and inflammation research, University of Southern Denmark, Odense, Denmark, ⁵Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ⁶Biomedicin, Aarhus University, 8000, Denmark
Background/Purpose: The complement system is one of the key players in the pathogenesis of systemic lupus erythematosus (SLE). Collectin liver 1 (CL-L1) and collectin kidney…
Abstract Number: 1200 • 2014 ACR/ARHP Annual Meeting
Plasma Levels of Pattern Recognition Molecules of the Lectin Pathway Are Altered in SLE Patients
Anne Troldborg^1,2, Steffen Thiel³, Magdalena Janina Laska³, Bent Deleuran^4,5, Jens Christian Jensenius³ and Kristian Stengaard-Pedersen^2,6, ¹clinical medicine, Aarhus University, Aarhus, Denmark, ²Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ³Biomedicine, Aarhus University, Aarhus, Denmark, ⁴Department of Biomedicine, Aarhus University, Aarhus, Denmark, ⁵Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ⁶Clinical medicine, Aarhus University, Aarhus, Denmark
Background/Purpose Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease where the Complement System plays a key role in the pathogenesis. The objective of this…

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