Abstracts tagged "innate immunity and prognostic factors"

Abstract Number: 2171 • 2014 ACR/ARHP Annual Meeting
Polymorphisms in theÂ FCN1Â Gene Coding for M-Ficolin Are Associated with Disease Activity, Radiographic Damage and Are the Strongest Predictors of DAS28 Remission in 180 DMARD naÃ¯ve Early Rheumatoid Arthritis Patients
Christian G. Ammitzbøll¹, Rudi Steffensen², Steffen Thiel³, Jens Christian Jensenius³, Kim Horslev-Petersen⁴, Torkell Ellingsen^5,6, Merete Lund Hetland⁷, Peter Junker⁸, Mikkel Ostergaard⁹ and Kristian Stengaard-Pedersen¹⁰, ¹Arhus University Hospital, Aarhus, Denmark, ²Department of Clinical Immunology, Aalborg University Hospital, Aalborg, Denmark, ³Biomedicine, Aarhus University, Aarhus, Denmark, ⁴Rheumatology, Research Unit at King Christian X Hospital for Rheumatic Diseases, Graasten, Graasten, Denmark, ⁵Reumatology, Odense University Hospital, Odense, Denmark, ⁶Diagnostic Center, Regional Hospital Silkeborg, Silkeborg, Denmark, ⁷DANBIO, Department of Rheumatology, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark, ⁸Department of Rheumatology, Odense University Hospital, Odense, Denmark, ⁹Dept of Rheumatology RM, Copenhagen University Hospital, Glostrup, Denmark, ¹⁰Rheumatology, Arhus University Hospital, Aarhus, Denmark
Background/Purpose: M-ficolin is a pattern recognition molecule that collaborates with associated serine proteases as an activator of the complement system. High M-ficolin levels are strongly…

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