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Abstracts tagged "innate immunity and ontogeny"

  • Abstract Number: 2806 • 2019 ACR/ARP Annual Meeting

    Single Cell RNA-sequencing Reveals Distinct Macrophage Subsets in the Joint with Differing Ontogenies During Steady-state and Arthritis

    Anna Montgomery 1, Shang-Yang Chen1, Philip Homan 1, Gaurav Gadhvi 1, Deborah Winter 2 and Harris Perlman 2, 1Northwestern University, Chicago, 2Northwestern University Feinberg School of Medicine, Division of Rheumatology, Chicago

    Background/Purpose: Macrophages in the synovial lining of the joint are critical players in the pathogenesis of rheumatoid arthritis (RA). However, their heterogeneity remains poorly characterized.Methods:…
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