Abstracts tagged "innate immunity and myositis"

Abstract Number: 2072 • 2013 ACR/ARHP Annual Meeting
Decreased Number Of Circulating NK Cells and Dramatic Lack Of IFN-Gamma Production In Patients With Antisynthetase Syndrome
Baptiste Hervier^1,2, Yves Allenbach^3,4, Fleur Cohen-Aubart⁵, Micheline Pha⁶, Lenaig Mescam-Mancini⁷, David Saadoun⁸, Alexis Mathian^5,6, Olivier Benveniste^9,10 and Vincent Vieillard¹, ¹INSERM UMR-S 1135, UPMC, Paris, France, ²Internal Medicine & Clinical Immunology Dpt, Pitié-Salpêtrière Hospital, APHP, Paris, France, ³Internal Medicine Dpt 1, Pitié-Salpêtrière Hospital, APHP, Paris, France, ⁴INSERM UMR974, UPMC, Paris, France, ⁵Internal Medicine Dpt 2, Pitié-Salpêtrière Hospital, APHP, Paris, France, ⁶INSERM UMR-S 945, UPMC, Paris, France, ⁷Pathology Dpt, University hospital, Grenoble, France, ⁸DHU 2iB Internal Medicine Referal Center for Autoimmune diseases Pitie Hospital, Paris, France, ⁹UMR 974, Sorbonne Universités, University Pierre et Marie-Curie-Paris 6, INSERM, Paris, France, ¹⁰Internal Medecine Dpt 1, Pitié-Salpêtrière Hospital, APHP, Paris, France
Background/Purpose: Antisynthetase syndrome (ASS) is a rare autoimmune myositis associated with interstitial lung disease (ILD) and characterized by specific anti-tRNA-synthetase autoantibodies (ARS). To date, the…

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