ACR Meeting Abstracts

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Abstracts tagged "infliximab"

  • Abstract Number: 365 • 2014 ACR/ARHP Annual Meeting

    Differential Relative Contribution of Individual Components on DAS28 over Time: An Analysis from the Prospective, Observational, Biological Treatment Registry Across Canada

    Denis Choquette1, Dalton Sholter2, Isabelle Fortin3, Michael Starr4, Carter Thorne5, Milton Baker6, Regan Arendse7, Philip Baer8, Michel Zummer9, Jude Rodrigues10, Maqbool Sheriff11, Emmanouil Rampakakis12, John S. Sampalis12, Francois Nantel13, Allen J Lehman14, Susan Otawa14 and May Shawi13, 1Rheumatology, Notre Dame Hospital, Montreal, QC, Canada, 2University of Alberta, Edmonton, AB, Canada, 3Centre de Rhumatologie de l'Est du Québec, Rimouski, QC, Canada, 4Montreal General Hospital, Montreal, QC, Canada, 5Southlake Regional Health Centre, Newmarket, ON, Canada, 6University of Victoria, Victoria, BC, Canada, 7University of Saskatchewan, Saskatoon, SK, Canada, 8Private Practice, Scarborough, ON, Canada, 9Université de Montréal, Montreal, QC, Canada, 10Clinical Research and Arthritis Centre, Windsor, ON, Canada, 11Nanaimo Regional General Hospital, Nanaimo, BC, Canada, 12JSS Medical Research, Montreal, QC, Canada, 13Janssen Inc., Toronto, ON, Canada, 14Medical Affairs, Janssen Inc., Toronto, ON, Canada

    Background/Purpose DAS28 is an important outcome for clinical research and practice assisting with therapeutic decisions. The main contributors to DAS28 are joint tenderness and acute-phase…
  • Abstract Number: 248 • 2014 ACR/ARHP Annual Meeting

    Is the Basdai Score Driven By Pain in Ankylosing Spondylitis Patients Treated with Anti-TNF?

    Proton Rahman1, Algis Jovaisas2, William Bensen3, Wojciech Olszynski4, Anna Jaroszynska5, Philip Baer6, Maqbool Sheriff7, Dalton Sholter8, Eliofotisti Psaradellis9, John S. Sampalis9, Francois Nantel10, Allen J Lehman11, Susan Otawa11 and May Shawi10, 1Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, 2194 Main Street, University of Ottawa, Ottawa, ON, Canada, 3Division of Rheumatology, McMaster University, Hamilton, ON, Canada, 4University of Saskatchewan, Saskatoon, SK, Canada, 5Private Practice, Burlington, ON, Canada, 6Private Practice, Scarborough, ON, Canada, 7Nanaimo Regional General Hospital, Nanaimo, BC, Canada, 8University of Alberta, Edmonton, AB, Canada, 9JSS Medical Research, Montreal, QC, Canada, 10Janssen Inc., Toronto, ON, Canada, 11Medical Affairs, Janssen Inc., Toronto, ON, Canada

    Background/Purpose The present standard for measuring disease activity in AS is the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) which focuses on five major symptoms…
  • Abstract Number: L14 • 2014 ACR/ARHP Annual Meeting

    Determination of Efficacy of Intra-Articular Infliximab Therapy in JIA Patients By 3D/4D Musculo-Skeletal Ultrasound

    Miroslav Harjacek1, Mandica Vidovic2, Lovro Lamot2,3, Marija Perica2 and Lana Tambic Bukovac2, 1Rheumatology, Children's Hospital Srebrnjak, Zagreb, Croatia, 2Children's Hospital Srebrnjak, Zagreb, Croatia, 3University of Zagreb School of Medicine, Zagreb, Croatia

    Background/Purpose: Intra-articular (IA) infliximab (IFX) is an attractive treatment option of chronic arthritis, but based on few heterogenic studies, outcome is still controversial. To investigate…
  • Abstract Number: 2763 • 2014 ACR/ARHP Annual Meeting

    Long-Term Outcome of Chronic Progressive Neurological Manifestations in Behcet’s Disease

    Shunsei Hirohata1, Hirotoshi Kikuchi2, Tetsuji Sawada3, Hiroko Nagafuchi4, Msataka Kuwana5, Mitsuhiro Takeno6 and Yoshiaki Ishigatsubo7, 1Int Med/Rheumatol & Infec Dis, Kitasato Univ School of Med, Kanagawa, Japan, 2Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan, 3Internal Medicine 3, Tokyo Medical University, Tokyo, Japan, 4Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan, 5Internal Medicine, Keio University School of Medicine, Tokyo, Japan, 6Clinical Laboratory Department, Yokohama City University Hospital, Yokohama, Japan, 7Int Med & Clin Immunology, Yokohama City Grad Schl of Med, Yokohama, Japan

    Background/Purpose: Chronic progressive neurological manifestations in Behcet's disease (BD) is characterized by progressive deterioration leading to disability either with or without a history of previous…
  • Abstract Number: 2496 • 2014 ACR/ARHP Annual Meeting

    Predictors of ACR/EULAR Boolean and SDAI Remission in Patients with Established Rheumatoid Arthritis Treated with Anti-TNF: An Analysis from the Prospective, Observational, Biological Treatment Registry Across Canada

    Boulos Haraoui1, Maqbool Sheriff2, Majed Khraishi3, Michael Starr4, John Kelsall5, Milton Baker6, Regan Arendse7, Sanjay Dixit8, William Bensen9, Philip Baer10, Rafat Faraawi8, Emmanouil Rampakakis11, John S. Sampalis11, Susan Otawa12, Allen J Lehman12, Francois Nantel13 and May Shawi13, 1Department of Medicine, Centre Hospitalier de l’Université de Montréal, Montréal, QC, Canada, 2Nanaimo Regional General Hospital, Nanaimo, BC, Canada, 3Nexus Clinical Research, St John's, NF, Canada, 4Montreal General Hospital, Montreal, QC, Canada, 5The Mary Pack Arthritis Centre, Vancouver, BC, Canada, 6University of Victoria, Victoria, BC, Canada, 7University of Saskatchewan, Saskatoon, SK, Canada, 8McMaster University, Hamilton, ON, Canada, 9Department of Medicine, Division of Rheumatology, Clinical Professor, McMaster University, Hamilton, ON, Canada, 10Private Practice, Scarborough, ON, Canada, 11JSS Medical Research, Montreal, QC, Canada, 12Medical Affairs, Janssen Inc., Toronto, ON, Canada, 13Janssen Inc., Toronto, ON, Canada

    Background/Purpose Early achievement of remission is associated with improved clinical, functional and radiographic outcomes1. Recent recommendations of the Canadian Rheumatology Association dictate that treatment target…
  • Abstract Number: 2411 • 2014 ACR/ARHP Annual Meeting

    Assessing Treatment Durability of Infliximab in the Management of Psoriatic Arthritis and Rheumatoid Arthritis Patients in a Canadian Setting

    John Kelsall1, Algis Jovaisas2, Proton Rahman3, Dalton Sholter4, Michael Starr5, William Bensen6, Maqbool Sheriff7, Wojciech Olszynski8, Michel Zummer9, Rafat Faraawi10, Andrew Chow11, Suneil Kapur12, Emmanouil Rampakakis13, John S. Sampalis13, Francois Nantel14, Susan Otawa15, May Shawi14 and Allen J Lehman15, 1The Mary Pack Arthritis Centre, Vancouver, BC, Canada, 2194 Main Street, University of Ottawa, Ottawa, ON, Canada, 3Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, 4University of Alberta, Edmonton, AB, Canada, 5Rheumatology, McGill University Health Centre, Montreal, QC, Canada, 6St Josephs Hospital and McMaster University, Hamilton, ON, Canada, 7Nanaimo Regional General Hospital, Nanaimo, BC, Canada, 8University of Saskatchewan, Saskatoon, SK, Canada, 9Université de Montréal, Montreal, QC, Canada, 10Medicine, McMaster University, Hamilton, ON, Canada, 11McMaster University, Hamilton and Credit Valley Hospital, Mississauga, ON, Canada, 12Rheumatology, University of Ottawa, Ottawa, ON, Canada, 13JSS Medical Research, Montreal, QC, Canada, 14Janssen Inc., Toronto, ON, Canada, 15Medical Affairs, Janssen Inc., Toronto, ON, Canada

    Background/Purpose: The efficacy of anti-TNF in the management of psoriatic arthritis (PsA) and rheumatoid arthritis (RA) has been demonstrated in numerous controlled clinical trials. The…
  • Abstract Number: 2458 • 2013 ACR/ARHP Annual Meeting

    Change Over Time In The Profile Of Ankylosing Spondylitis Patients Treated With Infliximab In Canadian Routine Care

    Denis Choquette1, Michael Starr2, Majed M. Khraishi3, William G. Bensen4, Saeed A. Shaikh5, Jude F. Rodrigues6, Dalton E. Sholter7, Maqbool K. Sheriff8, Julie Vaillancourt9, John S. Sampalis9, Allen J. Lehman10, Susan M. Otawa10, Francois Nantel11 and May Shawi12, 1Rheumatology, Institut de rhumatologie de Montréal (IRM), Montréal, QC, Canada, 2Montreal General Hospital, Montreal, QC, Canada, 3Nexus Clinical Research, St John's, NF, Canada, 4Department of Medicine, Division of Rheumatology, Clinical Professor, McMaster University, Hamilton, ON, Canada, 5Medicine, McMaster University, St Catharines, ON, Canada, 6Rheumatology, Windsor, ON, Canada, 7Rheumatology Associates, Edmonton, AB, Canada, 8Nanaimo Regional General Hospital, Nanaimo, BC, Canada, 9JSS Medical Research, Montreal, QC, Canada, 10Medical Affairs, Janssen Inc., Toronto, ON, Canada, 11Janssen Inc., Toronto, ON, Canada, 12Medical Affairs, Janssen Canada Inc, Toronto, ON, Canada

    Background/Purpose: Canadian provincial reimbursement policies in regards with infliximab coverage status have evolved in the last decade. The objective of this study was to describe…
  • Abstract Number: 2369 • 2013 ACR/ARHP Annual Meeting

    Long-Term Outcome Of Infliximab Therapy In Rheumatoid Arthritis Patients: Results From Japanese Multicenter Registry System

    Nobunori Takahashi1, Toshihisa Kojima2, Atsushi Kaneko3, Yuji Hirano4 and Naoki Ishiguro1, 1Orthopaedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan, 2Orthopedic Surgery and Rheumatology, Nagoya University Hospital, Nagoya, Japan, 3Orthopedic Surgery, Nagoya Medical Center, Nagoya, Japan, 4Rheumatology, Toyohashi Municipal Hospital, Toyohashi, Japan

    Background/Purpose: After demonstration of effectiveness of anti-tumor necrosis factor (TNF) agents in patients with rheumatoid arthritis (RA), their use has become common practice in treating…
  • Abstract Number: 2320 • 2013 ACR/ARHP Annual Meeting

    Ultrasonographic Monitoring Of Response To Infliximab In Patients With Rheumatoid Arthritis

    Xiaomei Leng1, Weiguo Xiao2, Xiaochun Zhu3, Zhonghui Xu1, Wei Yu1, Jing Lu2, Jiakai Wang2, Xiaoru Xia3, Yongji Li3, Yi Liu4, Yi Zhao4, Honghao Tang5, Dongbao Zhao6, Yeqing Shi6, Huji Xu7, Jun Bao7, Lin Chen7, Ling Lin7, Ling Zhou7, Guoqiang Chen8, Weihong Zhang8 and Yan Zhao1, 1Peking Union Medical College Hospital, Beijing, China, 2The First Hospital of China Medical University, Shenyang, China, 3The First Hospital of Wenzhou Medical College, Wenzhou, China, 4Department of Rheumatology and Immunology, West China Hospital of Sichuan University, Chengdu, China, 5West China Hospital of Sichuan University, Chengdu, China, 6Changhai Hospital of Shanghai, Shanghai, China, 7Shanghai Changzheng Hospital, Shanghai, China, 8The First People’s Hospital of Foshan, Foshan, China

     Background/Purpose: To evaluate the efficacy of treatment with infliximab on joint inflammation and bone erosion in rheumatoid arthritis (RA) patients using ultrasonography. Methods: 80 eligible…
  • Abstract Number: 2223 • 2013 ACR/ARHP Annual Meeting

    Monitoring Of Active Matrix Metalloproteinase-3 Using

    Sung Jae Choi1, Young Ho Seo2, Young Ho Lee3, Jong Dae Ji1, Gwan Gyu Song4, Aeju Lee2 and Jae-Hoon Kim4, 1Rheumatology, Korea University Medical Center, Seoul, South Korea, 2Rheumatology, Korea University Medical center, Seoul, South Korea, 3Internal Medicine, Rheumatology, Korea University Medical Center, Seoul, South Korea, 4Div of Rheum, Dept of Int Med, Korea Univ College of Med, Seoul, South Korea

    Background/Purpose: Active matrix metalloproteinase-3 (MMP-3) is a prognostic marker of rheumatoid arthritis (RA). Recently, we developed the MMP-3 probe which can specifically detect an active…
  • Abstract Number: 1554 • 2013 ACR/ARHP Annual Meeting

    Real-World Effectiveness Of Infliximab In The Treatment Of Psoriatic Arthritis Over 12 Months: The Canadian Experience

    Proton Rahman1, Majed M. Khraishi2, William Bensen3, John T. Kelsall4, Brian D. Hanna5, Craig Watts6, Emmanouil Rampakakis7, John S. Sampalis7, May Shawi8, Susan M. Otawa9 and Allen J. Lehman9, 1Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, 2Nexus Clinical Research, St John's, NF, Canada, 3St. Joseph's Hospital and McMaster University, Hamilton, ON, Canada, 4Mary Pack Arthritis Centre, Vancouver, Vancouver, BC, Canada, 5Rheumatology, McMaster University, Ontario, Kitchener, ON, Canada, 6Department of Rheumatology, McGill University and Montreal General Hospital, Sainte-Anne-de-Bellevue, QC, Canada, 7JSS Medical Research, Montreal, QC, Canada, 8Medical Affairs, Janssen Canada Inc, Toronto, ON, Canada, 9Medical Affairs, Janssen Inc., Toronto, ON, Canada

    Background/Purpose: The efficacy of anti-TNF in the management of psoriatic arthritis (PsA) has been demonstrated in numerous controlled clinical trials. Longitudinal observational studies assessing the…
  • Abstract Number: 532 • 2013 ACR/ARHP Annual Meeting

    Role Of Baseline C-Reactive Protein In Response To Infliximab Plus Naproxen Vs Naproxen Alone In Patients With Axial Spondyloarthritis

    J Sieper1, M Rudwaleit1, J Lenaerts2, J Wollenhaupt3, L Myasoutova4, S Park5, Y Song6, R Yao7, M Govoni8, D Chitkara9 and N Vastesaeger10, 1University Clinic Benjamin Franklin, Berlin, Germany, 2Practice Rheumatology, Hasselt, Belgium, 3Schön-Klinik, Hamburg, Germany, 4Kazan State Medical University, Kazan, Russia, 5Catholic University of Korea, Seoul, South Korea, 6Seoul National University, Seoul, South Korea, 7Merck & Co., Inc., Whitehouse Station, NJ, 8MSD Italy, Rome, Italy, 9Merck Sharp & Dohme, Kenilworth, NJ, 10Merck Sharp & Dohme, Brussels, Belgium

    Background/Purpose: Baseline inflammation has been shown to influence response to tumor necrosis factor alpha antagonist treatment in patients with axial spondyloarthritis (SpA). This study evaluated…
  • Abstract Number: 482 • 2013 ACR/ARHP Annual Meeting

    Methotrexate Use At Infliximab Initiation and Impact On Treatment Outcomes: An Analysis From A Canadian Registry

    Denis Choquette1, J. Carter Thorne2, John T. Kelsall3, Michel Zummer4, Michael Starr5, Maqbool K. Sheriff6, William G. Bensen7, Andrew Chow8, Philip Baer9, Emmanouil Rampakakis10, John S. Sampalis10, Francois Nantel11, Allen J. Lehman12, Susan M. Otawa12 and May Shawi13, 1Rheumatology, Institut de rhumatologie de Montréal (IRM), Montréal, QC, Canada, 2Southlake Regional Health Centre, Newmarket, ON, Canada, 3Mary Pack Arthritis Centre, Vancouver, Vancouver, BC, Canada, 4Rheumatology, Ch Maisonneuve-Rosemont, Montreal, QC, Canada, 5Montreal General Hospital, Montreal, QC, Canada, 6Nanaimo Regional General Hospital, Nanaimo, BC, Canada, 7Department of Medicine, Division of Rheumatology, Clinical Professor, McMaster University, Hamilton, ON, Canada, 8University of Toronto, McMaster University, Credit Valley Rheumatology, Mississauga, ON, Canada, 9Private Practice, Scarborough, ON, Canada, 10JSS Medical Research, Montreal, QC, Canada, 11Janssen Inc., Toronto, ON, Canada, 12Medical Affairs, Janssen Inc., Toronto, ON, Canada, 13Medical Affairs, Janssen Canada Inc, Toronto, ON, Canada

    Background/Purpose: Clinical trials of anti-TNF therapies have shown that concurrent methotrexate (MTX) therapy enhances the efficacy of infliximab (IFX)1. Data on the benefits of combination…
  • Abstract Number: 499 • 2013 ACR/ARHP Annual Meeting

    Efficacy and Safety Of Infliximab Or Adalimumab Vs Abatacept In Patients With Rheumatoid Arthritis and An Inadequate Response To Methotrexate: Attest-Ample Network Randomized Trial

    Robin Christensen1, Simon Tarp1, Daniel Furst2, Lars E. Kristensen3 and Henning Bliddal4, 1Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Denmark, 2David Geffen School of Medicine, University of California, Los Angeles, CA, 3Rheumatology, Department of Clinical Sciences, Lund, Section of Rheumatology, Lund University, Lund, Sweden, 4Department of Rheumatology, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Denmark

    Background/Purpose: Using combined data from the ATTEST [1] and AMPLE [2] study comparing infliximab and adalimumab with abatacept in patients with rheumatoid arthritis (RA), we…
  • Abstract Number: 473 • 2013 ACR/ARHP Annual Meeting

    Real-World Effectiveness and Safety Of Infliximab In The Treatment Of Rheumatoid Arthritis Over 5 Years: The Canadian Experience

    Denis Choquette1, William Bensen2, Andrew Chow3, John T. Kelsall4, Maqbool K. Sheriff5, Jude F. Rodrigues6, Emmanouil Rampakakis7, John S. Sampalis7, May Shawi8, Francois Nantel9, Susan M. Otawa10 and Allen J. Lehman10, 1Rheumatology, Institut de rhumatologie de Montréal (IRM), Montréal, QC, Canada, 2St. Joseph's Hospital and McMaster University, Hamilton, ON, Canada, 3University of Toronto, McMaster University, Credit Valley Rheumatology, Mississauga, ON, Canada, 4Mary Pack Arthritis Centre, Vancouver, Vancouver, BC, Canada, 5Nanaimo Regional General Hospital, Nanaimo, BC, Canada, 6Rheumatology, Windsor, ON, Canada, 7JSS Medical Research, Montreal, QC, Canada, 8Medical Affairs, Janssen Canada Inc, Toronto, ON, Canada, 9Janssen Inc., Toronto, ON, Canada, 10Medical Affairs, Janssen Inc., Toronto, ON, Canada

    Background/Purpose:   Efficacy and safety of anti-TNF in rheumatoid arthritis (RA) management has been demonstrated in numerous controlled clinical trials. Longitudinal observational studies assessing the…
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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying financial and other sponsors about this policy. If you have questions about the abstract embargo policy, please contact the public relations department at [email protected].

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