Abstract Number: 1461 • 2015 ACR/ARHP Annual Meeting
Inflammatory Bowel Disease in Children with Systemic Juvenile Idiopathic Arthritis
Background/Purpose: Systemic juvenile idiopathic arthritis (sJIA) is an autoinflammatory disease accompanied by systemic symptoms including lymphadenopathy, serositis, and hepatosplenomegaly. Recently, we encountered a patient previously…Abstract Number: 2827 • 2015 ACR/ARHP Annual Meeting
Analysis of HLA-B27 Transgenic Rats Reveals Specific Gut Transcriptome and Microbiome Signatures Associated with Inflammation
Background/Purpose: HLA-B27 and human beta 2-microglobulin expression in rats (transgenic; TG) induces a spontaneous inflammatory disease resembling human spondyloarthritis (SpA) with associated gastrointestinal inflammation. While…Abstract Number: 2828 • 2015 ACR/ARHP Annual Meeting
Profiling Immunogenic Bacteria within the Microbiota of ZAP-70 Mutant SKG Mice Associated with Spondyloarthritis and Ileitis Using IgA-SEQ
Background/Purpose: IgA production is the main barrier mechanism of mucosal surfaces. High affinity IgA is generated through T cell-dependent mechanisms and preferentially binds to invasive…Abstract Number: 1919 • 2014 ACR/ARHP Annual Meeting
HLA-B27 Expression Shapes the Intestinal Microbiota
Background/Purpose The intestinal microbiota plays a central role in both health and disease. Beyond shaping local immune responses in the gut, it is increasingly clear…Abstract Number: 804 • 2014 ACR/ARHP Annual Meeting
Vasculitis and Inflammatory Bowel Diseases: A Study of 32 Patients with Both Conditions and Systematic Review of the Literature
Background/Purpose: Small case series suggested that vasculitis and inflammatory bowel disease (IBD; Crohn’s disease [CD] or ulcerative colitis [UC]) can co-occur more commonly than the…Abstract Number: 618 • 2014 ACR/ARHP Annual Meeting
A Gender Bias in Gut Microbiota of SKG Mice Colonized with a Limited Bacterial Consortium Associated with Severity of Spondyloarthritis and Ileitis Triggered By Beta-Glucan
Background/Purpose Beta-glucan (curdlan)-treated BALB/c ZAP-70W163C(SKG) mutant mice develop IL-23-dependent spondyloarthritis, and curdlan promotes ileitis in SKG mice housed under specific pathogen-free (SPF) but not germ-free…Abstract Number: 485 • 2014 ACR/ARHP Annual Meeting
Incidence of Clinical and Serological Lupus-like Disease during Anti-Tnfα-Treatment – a Two-Year Prospective Study in an Interdisciplinary Patient Cohort
Background/Purpose: TNFα-Inhibitors are the most widely used biological agents in rheumatic conditions or other chronic inflammatory diseases. Over the last ten years, the occurrence of…Abstract Number: 1115 • 2013 ACR/ARHP Annual Meeting
Prevalence Of Structural and Inflammatory Sacroiliitis, Assessed Using Computed Tomography and MR Imaging, In Inflammatory Bowel Disease: A Retrospective Study In 78 Patients
Background/Purpose: The primary objective was to assess the prevalence of structural and inflammatory sacroiliitis on computed tomography (CT) and MRI in inflammatory bowel disease (IBD).…Abstract Number: 268 • 2013 ACR/ARHP Annual Meeting
Inflammatory Bowel Disease In Juvenile Idiopathic Arthritis Patients Upon Biologics
Background/Purpose: Inflammatory bowel disease (IBD) is a matter of interest in patients with juvenile idiopathic arthritis (JIA) treated with biologics. Methods: Baseline demografics, clinical characteristics…Abstract Number: 1930 • 2012 ACR/ARHP Annual Meeting
Progranulin Plays a Protective Role in the Pathogenesis of Inflammatory Bowel Disease
Background/Purpose: Progranulin (PGRN) is a growth factor with multiple functions. We recently reported that PGRN and its derived engineered protein Atsttrin directly bound to TNF…Abstract Number: 1662 • 2012 ACR/ARHP Annual Meeting
Anti-IL-6 Therapy Impairs Intestinal Repair Through Inhibition of Epithelial Proliferation After Injury
Background/Purpose: Inhibition of IL-6 is used for treatment of rheumatoid arthritis and now being investigated as biologic therapy for a wide variety of autoimmune conditions,…Abstract Number: 1618 • 2012 ACR/ARHP Annual Meeting
Prevalence of Inflammatory Sacroiliitis Assessed On MR Imaging of Inflammatory Bowel Disease: A Retrospective Study Performed On 186 Patients
Background/Purpose: Articular involvements are by far the most common extra-intestinal manifestations in inflammatory bowel disease (IBD). They include peripheral arthritis and inflammatory axial manifestation. Until…Abstract Number: 1592 • 2012 ACR/ARHP Annual Meeting
A Novel Approach to the Early Detection of Axial Spondyloarthritis in Patients with Inflammatory Bowel Disease: The Implementation of an Advanced Practice Physiotherapist Led Screening Program
Background/Purpose: The prevalence of SpA in patients with inflammatory bowel disease (IBD) ranges from 3.1 - 10%, compared toAbstract Number: 1356 • 2012 ACR/ARHP Annual Meeting
Gender Differences Among Spondylitis Associated with Psoriasis, Inflammatory Bowel Disease and Primary Ankylosing Spondylitis
Background/Purpose: Differences regarding gender in primary Ankylosing Spondylitis are well known. However, there is less evidence regarding Spondylitis Associated with Psoriasis and that associated with…Abstract Number: 2627 • 2012 ACR/ARHP Annual Meeting
Gender Differences of Concepts Important to People Living with Crohn’s Disease and Their Coverage by Commonly Used Patient-Reported Outcome Instruments: Patient’s Perspective Elevated by a Qualitative Study
Background/Purpose: Crohn's disease (CD) has a major impact on functioning, health and well-being and patient-reported outcome (PRO) instruments have not been analysed from the perspective…
ACR Meeting Abstracts