ACR Meeting Abstracts

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Abstracts tagged "inflammatory bowel disease (IBD) and spondylarthritis"

  • Abstract Number: 1652 • 2018 ACR/ARHP Annual Meeting

    Musculoskeletal Involvement in Inflammatory Bowel Disease’S Patients: A Mono Centric Experience

    Andrea Delle Sedie1, Linda Ceccarelli2, Linda Carli1, Francesco Costa3, Santino Marchi3 and Marta Mosca1, 1Rheumatology Unit, University of Pisa, Pisa, Italy, 2University Gastroenterology Unit, University of Pisa, Pisa, Italy, 3University Gastroenterology Unit, University of Pisa,, Pisa, Italy

    Background/Purpose: Musculoskeletal symptoms are frequently reported by patients with inflammatory bowel diseases (IBD). Those symptoms may vary from arthralgia to arthritis, involving peripheral or axial…
  • Abstract Number: 2828 • 2018 ACR/ARHP Annual Meeting

    Utility of Fecal Calprotectin Levels for the Diagnosis of Inflammatory Bowel Disease in Patients with Spondylorarthritis

    Maria Espinosa1, Consuelo Ramos Giraldez1, Carolina Merino1, Belen Ruiz Antoran2, Jose Campos1, Carmen Barbadillo3, Hilda Godoy3, Belen Agudo4, Yago Gonzalez4, Jose Luis Andreu5 and Jesus Sanz1, 1Rheumatology, H.U. Puerta de Hierro, Madrid, Spain, 2Pharmacology, H.U. Puerta de Hierro, Madrid, Spain, 3H.U. Puerta de Hierro, Madrid, Spain, 4Gastroenterology, H.U. Puerta de Hierro, Madrid, Spain, 5Hospital Universitario Puerta de Hierro, Madrid, Spain

    Background/Purpose: It is estimated that between 5 and 10% of patients with spondyloarthritis (SpA) are associated with inflammatory bowel disease (IBD).The purpose of our study…
  • Abstract Number: 2512 • 2017 ACR/ARHP Annual Meeting

    Impact of Inflammatory Bowel Disease in Early Spondyloarthritis in a Prospective Longitudinal Cohort

    Daniel Wendling1, Xavier Guillot2, Clément Prati3, Rik Lories4 and Maxime Dougados5, 1Service de Rhumatologie, CHU Jean Minjoz, Besancon, France, 2EA 4267 FDE, FHU INCREASE, Université de Bourgogne FrancheComté, Besançon, France, 3Service de Rhumatologie, CHU J Minjoz, Besancon, France, 4Skeletal Biology and Engineering Research Center, KU Leuven, Leuven, Belgium, 5Rheumatology Department, Paris-Descartes University and Cochin Hospital, Paris, France

    Background/Purpose: Inflammatory bowel disease (IBD) is a classical extra articular feature of spondyloarthritis (SpA), with increasing evidence of a pathophysiological relationship. The aims of this…
  • Abstract Number: 1712 • 2015 ACR/ARHP Annual Meeting

    Development of a Novel SI Joint CT Score for Diagnosis of Axial Spondylitis

    Jonathan Chan1,2, Ismail Sari3,4, David Salonen5, Robert D Inman6 and Nigil Haroon7, 1Rheumatology, Spondylitis program, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 2Rheumatology, University of British Columbia, Vancouver, BC, Canada, 3Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 4Rheumatology, Dokuz Eylul University School Of Medicine, Department Of Internal Medicine, Division Of Rheumatology, Izmir, Turkey, 5Department of Medical Imaging, University Health Network, Toronto, ON, Canada, 6Immunlogy and Institute of Medical Science, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 7Rheumatology, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: The diagnosis of ankylosing spondylitis (AS) is based on pelvic radiographs plagued by poor sensitivity, specificity, and reproducibility. Many AS patients, particularly those with…
  • Abstract Number: 1723 • 2015 ACR/ARHP Annual Meeting

    Prevalence of Sacroiliitis in Inflammatory Bowel Disease Using a Standardized CT Scoring System

    Jonathan Chan1, Ismail Sari2, David Salonen3, Mark S. Silverberg4, Nigil Haroon2 and Robert D Inman5, 1Rheumatology, Spondylitis program, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 2Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 3Department of Medical Imaging, University Health Network, Toronto, ON, Canada, 4Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital IBD Group,, Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, ON, Canada, 5Immunlogy and Institute of Medical Science, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Previous studies assessing the prevalence of sacroiliitis in patients with inflammatory bowel disease (IBD) using CT scans have relied on the general impression of…
  • Abstract Number: 1724 • 2015 ACR/ARHP Annual Meeting

    Abdominal X-Rays Can Reliably Detect the Majority of CT Positive Sacroiliitis in an IBD Cohort

    Jonathan Chan1, Ismail Sari2, Ahmed Omar2, Mark S. Silverberg3, David Salonen4, Robert D Inman5 and Nigil Haroon2, 1Rheumatology, Spondylitis program, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 2Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 3Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital IBD Group,, Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, ON, Canada, 4Department of Medical Imaging, University Health Network, Toronto, ON, Canada, 5Immunlogy and Institute of Medical Science, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada

    Background/Purpose: There is a well-documented association between inflammatory bowel disease (IBD) and ankylosing spondylitis (AS). The hallmark feature of AS is the presence of sacroiliitis…
  • Abstract Number: 1740 • 2015 ACR/ARHP Annual Meeting

    Anti-Cyclic Citrullinated Peptide Antibodies and Inflammatory Bowel Disease 

    Jaita Mukherjee1, Maria Mouyis1, Kavina Shah1, Mohammad Mahdi Saeidinejad1, Ayesha Akbar2 and Shahir Hamdulay1, 1Rheumatology, Northwick Park Hospital, Middlesex, United Kingdom, 2Gastroenterology, Northwick Park Hospital, Middlesex, United Kingdom

    Background/Purpose: Enteropathic arthropathy refers to the pattern of inflammatory arthritis seen in association with gastrointestinal pathology. Arthritis in the presence of inflammatory bowel disease can…
  • Abstract Number: 2556 • 2014 ACR/ARHP Annual Meeting

    Is the Degree of NSAID Treatment in Early Axial Spondyloarthritis a Reflection of the physician’s Diagnosic Confidence? Results from the DESIR Cohort

    Anna Moltó1,2, Benjamin Granger3, Daniel Wendling4, Maxime Dougados5 and Laure Gossec6, 1GRC-UPMC 08 (EEMOIS); UPMC Univ Paris 06.AP-HP, Pitié Salpêtrière Hospital, Department of Rheumatology, Paris, France., Paris, France, 2Paris Descartes University, Rheumatology Department, Cochin Hospital, AP-HP. INSERM (U1153): Clinical Epidemiology and Biostatistics, PRES Sorbonne Paris-Cité, Paris, France., Paris, France, 3Biostatistics - GRC08-EEMOIS, Université Pierre et Marie Curie - Paris 6 ; AP-HP, Paris, France, 4Service de Rhumatologie, CHU J Minjoz, Besancon, France, 5INSERM (U1153): Clinical Epidemiology and Biostatistics, PRES Sorbonne Paris-Cité, Paris, France., Paris, France, 6Rheumatology, UPMC GRC08, Paris 06 University, Pitié Salpétrière Hospital, Paris, France

    Background/Purpose: Non-steroidal anti-inflammatory drugs (NSAIDs) are the keystone in the treatment of axial Spondyloarthritis (axSpA).  Diagnosis is often not easy in early forms due to…
  • Abstract Number: 615 • 2014 ACR/ARHP Annual Meeting

    Analysis of the Gut Transcriptome in HLA-B27 Transgenic Rats By RNA-Seq Reveals Prominent Interferon and IL-23/IL-17 Axis Signatures

    Tejpal Gill1, Mark Asquith2, Steve Brooks1, James T. Rosenbaum2 and Robert A. Colbert1, 1NIAMS/NIH, Bethesda, MD, 2OHSU, Portland, OR

    Background/Purpose: Expression of HLA-B27 and human beta 2-microglobulin (hb2m) in rats induces a spontaneous inflammatory disease resembling human spondyloarthritis (SpA). SpA overlaps with IBD in…
  • Abstract Number: 611 • 2014 ACR/ARHP Annual Meeting

    Autophagy and Unfolded Protein Response: A Fine Balance That Can Influence the Pathogenesis of Ankylosing Spondylitis and Inflammatory Bowel Disease

    Nigil Haroon1, Giuliana Guggino2, Zhenbo Zhang1, Kirby Yee3, Hasan Abdullah4, Ricardo Alessandro5, Stefania Raimondo5, Giovanni Triolo5 and Francesco Ciccia2, 1Toronto Western Research Institute, Toronto, ON, Canada, 2Rheumatology Unit, University of Palermo, Palermo, Italy, 3McMaster University, Hamilton, ON, Canada, 4University of Toronto, Toronto, ON, Canada, 5University of Palermo, Palermo, Italy

    Background/Purpose We have shown an increase in the unfolded protein response (UPR) with decreased ERAP1 or ERAP2 function in an in vitrosystem. Similarly UPR has…
  • Abstract Number: 527 • 2013 ACR/ARHP Annual Meeting

    Presence Of Gastrointestinal Symptoms and Autoantibodies In Patients With Spondyloarthritis In A Colombian Population

    Consuelo Romero-Sanchez1,2,3, Wilson Bautista-Molano1,4, Diana M Munoz C1, Viviana Parra I1, Alejandro Escobar1, Carlos Martínez5, Ferney Garcia5, Daniel Herrera6, Sebastían Segura1, Juliette De Ávila3, Ana MAría Mesa1, Haroldo Juliao7, John Londono1 and Rafael Valle-Oñate8,9, 1Rheumatology, Spondyloarthropathy Group, Rheumatology Department, Hospital Militar Central/Universidad de La Sabana, Bogotá, Colombia, 2Rheumatology, Universidad Militar Nueva Granada, Bogotá, Colombia, 3School of Dentistry, UIBO Institute (Oral Basic Research Unit),School of Dentistry, Universidad El Bosque, Bogotá, Colombia, 4Universidad Militar Nueva Granada, Bogotá, Colombia, 5Coloproctology, Coloproctology Deparment, Hospital Militar Central, Bogotá, Colombia, 6Genetic, Instituto de Genética Humana, Facultad de Medicina, Pontificia Universidad Javeriana, Bogotá, Colombia, 7Gastroenterology, Gastroenterology Deparment, Hospital Militar Central, Bogotá, Colombia, 8Spondyloarthritis Group. Rheumatology Department. Hospital Militar Central/Universidad de La Sabana. Bogotá. Colombia, Bogotá, Colombia, 9Rheumatology, Faculty of Medicine, Universidad Militar Nueva Granada, Bogotá, Colombia

    Background/Purpose: The frequency of gastrointestinal (GI) involvement in spondyloarthritis (SpA) ranges from 21% to 30% and 5% to 10% are associated with inflammatory bowel disease…
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