Abstracts tagged "inflammatory bowel disease (IBD) and microbiome"

Abstract Number: 1913 • 2017 ACR/ARHP Annual Meeting
Inter-Omic Analysis Reveals Functional Relationship between Diverse Gut Microbiota and Dysregulated Host Immune Response in HLA-B27-Mediated Experimental Spondyloarthritis
Tejpal Gill¹, Stephen R. Brooks², Mark Asquith³, James T. Rosenbaum⁴ and Robert Colbert⁵, ¹National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ²Biodata Mining and Discovery Section, Office of Science and Technology, NIAMS/NIH, Bethesda, MD, ³Oregon Health & Science University, Portland, OR, ⁴Ophthalmology, Oregon Health & Science University and Legacy Devers Eye Institute, Portland, OR, ⁵NIAMS/NIH, Bethesda, MD
Background/Purpose: HLA-B27 has been hypothesized to alter gut microbiota and host-microbe interactions to promote spondyloarthritis (SpA). In HLA-B27 transgenic (HLA-B27 Tg) rats with experimental SpA,…

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Abstracts tagged "inflammatory bowel disease (IBD) and microbiome"

Inter-Omic Analysis Reveals Functional Relationship between Diverse Gut Microbiota and Dysregulated Host Immune Response in HLA-B27-Mediated Experimental Spondyloarthritis