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Abstracts tagged "inflammatory arthritis and rheumatoid arthritis"

  • Abstract Number: 2878 • ACR/ARHP Annual Meeting 2014

    G Protein Signaling Modulator 3 (GPSM3) Deficiency Is Protective in Inflammatory Arthritis Models and Altered GPSM3 Gene Products Correlate with Single Nucleotide Polymorphisms in Humans

    Teresa K. Tarrant1, D. Stephen Serafin2, Elizabeth Sugg2, Roman Timoshchenko2, Matthew J. Billard2, David P. Siderovski3 and Kristy Richards4, 1Medicine/Rheumatology, Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 3Physiology and Pharmacology, West Virginia University School of Medicine, Morgantown, WV, 4Medicine, Dept. of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC

    Background/Purpose GPSM3, a newly described regulator of heterotrimeric G protein signaling, is selectively expressed in hematopoietic cells with high expression in monocytes.  We have shown…

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