Abstracts tagged "inflammatory arthritis and rheumatoid arthritis"

Abstract Number: 2878 • 2014 ACR/ARHP Annual Meeting
G Protein Signaling Modulator 3 (GPSM3) Deficiency Is Protective in Inflammatory Arthritis Models and Altered GPSM3 Gene Products Correlate with Single Nucleotide Polymorphisms in Humans
Teresa K. Tarrant¹, D. Stephen Serafin², Elizabeth Sugg², Roman Timoshchenko², Matthew J. Billard², David P. Siderovski³ and Kristy Richards⁴, ¹Medicine/Rheumatology, Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, ²Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, ³Physiology and Pharmacology, West Virginia University School of Medicine, Morgantown, WV, ⁴Medicine, Dept. of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC
Background/Purpose GPSM3, a newly described regulator of heterotrimeric G protein signaling, is selectively expressed in hematopoietic cells with high expression in monocytes. We have shown…

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