Abstracts tagged "inflammatory arthritis and regulatory cells"

Abstract Number: 900 • 2012 ACR/ARHP Annual Meeting
Deletion of RBP-J in a Murine Model of Inflammatory Arthritis Reveals Differential Pro-Inflammatory Cytokine and FoxP3 Gene Expression
Soumya D. Chakravarty¹, Karmen Au², Xiaoyu Hu³ and Lionel B. Ivashkiv⁴, ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Hospital for Special Surgery, New York, NY, ³Arthritis Tissue Degeneration Program, Hospital for Special Surgery, New York, NY, ⁴Arthritis and Tissue Degeneration Program and the David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, NY
Background/Purpose: The DNA-binding protein RBP-J serves as the central transcriptional regulator of the Notch signaling pathway. Prior work done using a knockdown approach of RBP-J…

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Abstracts tagged "inflammatory arthritis and regulatory cells"

Deletion of RBP-J in a Murine Model of Inflammatory Arthritis Reveals Differential Pro-Inflammatory Cytokine and FoxP3 Gene Expression