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Abstracts tagged "inflammation and therapy"

  • Abstract Number: 790 • 2017 ACR/ARHP Annual Meeting

    Pre-Clinical Evidences of Immunomodulatory Activities of Tuftsin-Phosphorylcholine on Samples from Patients with Giant Cell Arteritis in Comparison to Corticosteroids

    Stefania Croci1, Martina Bonacini1, Francesco Muratore2,3, Andrea Caruso3, Antonio Fontana4, Luigi Boiardi3, Alessandra Soriano3,5, Alberto Cavazza6, Luca Cimino7, Lucia Belloni1, Maria Parmeggiani1, Miri Blank8,9, Yehuda Shoenfeld8,9 and Carlo Salvarani2,3, 1Unit of Clinical Immunology, Allergy and Advanced Biotechnologies, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy, Reggio Emilia, Italy, 2University of Modena and Reggio Emilia, Italy, Modena, Italy, 3Unit of Rheumatology, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy, Reggio Emilia, Italy, 4Unit of Vascular Surgery, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy, Reggio Emilia, Italy, 5Campus Bio-Medico, University of Rome, Italy, Roma, Italy, 6Unit of Pathology, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy, Reggio Emilia, Italy, 7Unit of Ocular Immunology, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy, Reggio Emilia, Italy, 8Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Israel, Ramat-Gan, Israel, 9Sackler Faculty of Medicine, Tel-Aviv University, Israel, Tel-Aviv, Israel

    Background/Purpose: Tuftsin-PhosphorylCholine (TPC) is a novel bi-specific molecule which has shown immunomodulatory effects in experimental mouse models of lupus, colitis and arthritis but data in…
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