Abstracts tagged "inflammation and tendonitis/bursitis"

Abstract Number: 413 • ACR/ARHP Annual Meeting 2018
S100A8 & S100A9: Alarmin Mediated Inflammation in Tendinopathy
Lindsay A N Crowe¹, Michael McLean², Emma Garcia-Melchor², Katharina Patommel², Susan M Kitson², James H Reilly³, Iain B. McInnes^2,3, Moeed Akbar² and Neal L Millar², ¹Insititute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom, ²Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom, ³University of Glasgow, Glasgow, United Kingdom
Background/Purpose: Alarmins, also referred to as damage associated molecular patterns (DAMPS), are endogenous molecules mobilized in response to tissue damage and are known to activate…
Abstract Number: 1104 • ACR/ARHP Annual Meeting 2016
Discovery of a Small Molecule Inhibitor of the Wnt Pathway (SM04755) As a Potential Topical Treatment for Chronic Tendinopathy
Vishal Deshmukh¹, Timothy Seo¹, Maureen Ibanez¹, Luis Dellamary¹, Josh Stewart¹, John Hood² and Yusuf Yazici¹, ¹Samumed, LLC, San Diego, CA, ²Samumed, LLC (formerly), San Diego, CA
Background/Purpose: Chronic tendinopathy is an inflammatory and degenerative condition caused by injuries or overuse. Current therapeutic options focus on alleviating the symptoms and pain rather…