inflammation and synovium Archives - ACR Meeting Abstracts

Abstract Number: 1149 • ACR/ARHP Annual Meeting 2015
The Active Metabolite of Fostamatinib, R406, Only Decreases the Inflammation-Driven Extracellular Matrix Turnover of the Joint at High Concentrations Ex Vivo
Cecilie F. Kjelgaard-Petersen^1,2, Christian S. Thudium¹, Anne Sofie Siebuhr¹, Thorbjørn G. Christiansen³, Morten Asser Karsdal¹, Per Hägglund² and Anne C. Bay-Jensen⁴, ¹Biomarkers and Research, Nordic Bioscience, Herlev, Denmark, ²Systems Biology, Technical University of Denmark, Kgs. Lyngby, Denmark, ³Gentofte University Hospital, Orthopaedicsurgery unit, Gentofte, Denmark, ⁴Biomarkers and Research, Rheumatology, Nordic Bioscience, Herlev, Denmark
Background/Purpose: Osteoarthritis (OA) and rheumatoid arthritis are degenerative diseases of the whole joint. The extracellular matrix (ECM) turnover is highly regulated in response to the…

Abstracts tagged "inflammation and synovium"